STRINGSTRING
Znf516 Znf516 Atf2 Atf2 Sptlc2 Sptlc2 I79_005787 I79_005787 I79_006232 I79_006232 Sh3pxd2b Sh3pxd2b Rasal2 Rasal2 Sox8 Sox8 I79_008252 I79_008252 Creb5 Creb5 I79_008467 I79_008467 I79_008576 I79_008576 I79_008980 I79_008980 Bbs4 Bbs4 H671_1g1417 H671_1g1417 Adrm1 Adrm1 Oxct1 Oxct1 Arid5b Arid5b Umodl1 Umodl1 I79_011789 I79_011789 Xbp1 Xbp1 Hmgcs2 Hmgcs2 CgPICR_018825 CgPICR_018825 Ppard Ppard I79_014480 I79_014480 I79_014481 I79_014481 I79_014482 I79_014482 Dgat2 Dgat2 Slc25a25 Slc25a25 I79_015169 I79_015169 I79_015205 I79_015205 Ppargc1a Ppargc1a Ebf2 Ebf2 I79_016407 I79_016407 Arrdc3 Arrdc3 Acat1 Acat1 Pik3ca Pik3ca I79_017430 I79_017430 Hras Hras I79_018445 I79_018445 Lrp5 Lrp5 Ap1s2 Ap1s2 Enpp1 Enpp1 I79_021840 I79_021840 Amer1 Amer1 I79_022371 I79_022371 Csf1 Csf1 I79_023496 I79_023496 I79_023498 I79_023498 Bscl2 Bscl2 Guca2b Guca2b Paxip1 Paxip1 Dhrs7b Dhrs7b I79_002659 I79_002659 Lep Lep I79_003729 I79_003729
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Znf516Zinc finger protein 516. (1148 aa)
Atf2Cyclic AMP-dependent transcription factor ATF-2. (487 aa)
Sptlc2Serine palmitoyltransferase 2. (425 aa)
I79_005787Serine palmitoyltransferase 2. (77 aa)
I79_006232PAX-interacting protein 1. (79 aa)
Sh3pxd2bSH3 and PX domain-containing protein 2B. (880 aa)
Rasal2Ras GTPase-activating protein SynGAP. (161 aa)
Sox8Transcription factor SOX-8. (463 aa)
I79_008252Guanylate cyclase activator 2B. (104 aa)
Creb5Cyclic AMP-responsive element-binding protein 5. (164 aa)
I79_008467Cyclic AMP-responsive element-binding protein 5. (228 aa)
I79_008576Pumilio-like 2. (1064 aa)
I79_008980Bardet-Biedl syndrome 4 protein-like. (104 aa)
Bbs4Bardet-Biedl syndrome 4 protein-like. (125 aa)
H671_1g1417Spartin isoform 2. (616 aa)
Adrm1Proteasomal ubiquitin receptor ADRM1. (407 aa)
Oxct1Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (520 aa)
Arid5bAT-rich interactive domain-containing protein 5B. (945 aa)
Umodl1Uromodulin-like 1. (1351 aa)
I79_011789DNA-binding protein inhibitor ID-2. (185 aa)
Xbp1X-box binding protein 1 isoform 1. (330 aa)
Hmgcs23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
CgPICR_018825Cell division protein kinase 4. (121 aa)
PpardPeroxisome proliferator-activated receptor delta. (440 aa)
I79_014480Vacuolar protein sorting-associated protein 13B. (2571 aa)
I79_014481Vacuolar protein sorting-associated protein 13B. (617 aa)
I79_014482Vacuolar protein sorting-associated protein 13B. (239 aa)
Dgat2Diacylglycerol O-acyltransferase 2. (388 aa)
Slc25a25Calcium-binding mitochondrial carrier protein SCaMC-2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (65 aa)
I79_015169Ras GTPase-activating protein nGAP. (1105 aa)
I79_015205Cell division protein kinase 4; Belongs to the protein kinase superfamily. (367 aa)
Ppargc1aPeroxisome proliferator-activated receptor gamma coactivator 1-alpha. (894 aa)
Ebf2Transcription factor COE2. (553 aa)
I79_016407Arrestin domain-containing protein 3. (98 aa)
Arrdc3Arrestin domain-containing protein 3. (194 aa)
Acat1Acetyl-CoA acetyltransferase, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family. (424 aa)
Pik3caPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (86 aa)
I79_017430Selenoprotein M. (95 aa)
HrasGTPase HRas-like protein. (189 aa)
I79_018445F-box-like/WD repeat-containing protein TBL1XR1. (429 aa)
Lrp5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1608 aa)
Ap1s2AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (154 aa)
Enpp1Ectonucleotide pyrophosphatase/phosphodiesterase family member 1. (906 aa)
I79_021840Nuclear receptor ROR-gamma. (341 aa)
Amer1Protein FAM123B. (1113 aa)
I79_022371Cell division protein kinase 4. (143 aa)
Csf1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (552 aa)
I79_023496Seipin. (71 aa)
I79_023498Seipin. (163 aa)
Bscl2Leucine-rich repeat neuronal protein 4. (224 aa)
Guca2bGuanylate cyclase activator 2B. (107 aa)
Paxip1PAX-interacting protein 1. (91 aa)
Dhrs7bDehydrogenase/reductase SDR family member 7B; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (324 aa)
I79_002659High mobility group protein HMGI-C. (103 aa)
LepLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
I79_003729Protein fto. (502 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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