(14 nodes) Mammary gland epithelial cell differentiation network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	I79_011789	DNA-binding protein inhibitor ID-2. (185 aa)
	Lbh	Protein LBH. (88 aa)
	Smo	Smoothened-like; Belongs to the G-protein coupled receptor Fz/Smo family. (984 aa)
	Znf703	Zinc finger protein 703. (143 aa)
	Irf6	Interferon regulatory factor 6. (467 aa)
	Lats1	Serine/threonine-protein kinase LATS1. (1130 aa)
	I79_005331	Receptor tyrosine-protein kinase erbB-4. (480 aa)
	I79_007089	Receptor tyrosine-protein kinase erbB-4. (225 aa)
	I79_007090	Receptor tyrosine-protein kinase erbB-4. (182 aa)
	PRLR	Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (605 aa)
	Hif1a	Hypoxia-inducible factor 1 alpha. (820 aa)
	Ptch1	Protein patched-like 1. (1114 aa)
	Foxb1	Forkhead box protein B1. (325 aa)
	Foxf1	Forkhead box protein F1. (320 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
I79_005331	I79_007089	G3H4W8	G3H9L3	Receptor tyrosine-protein kinase erbB-4.	Receptor tyrosine-protein kinase erbB-4.	0.899
I79_005331	I79_007090	G3H4W8	G3H9L4	Receptor tyrosine-protein kinase erbB-4.	Receptor tyrosine-protein kinase erbB-4.	0.899
I79_007089	I79_005331	G3H9L3	G3H4W8	Receptor tyrosine-protein kinase erbB-4.	Receptor tyrosine-protein kinase erbB-4.	0.899
I79_007089	I79_007090	G3H9L3	G3H9L4	Receptor tyrosine-protein kinase erbB-4.	Receptor tyrosine-protein kinase erbB-4.	0.931
I79_007090	I79_005331	G3H9L4	G3H4W8	Receptor tyrosine-protein kinase erbB-4.	Receptor tyrosine-protein kinase erbB-4.	0.899
I79_007090	I79_007089	G3H9L4	G3H9L3	Receptor tyrosine-protein kinase erbB-4.	Receptor tyrosine-protein kinase erbB-4.	0.931
Ptch1	Smo	G3IJP5	G3GZ55	Protein patched-like 1.	Smoothened-like; Belongs to the G-protein coupled receptor Fz/Smo family.	0.998
Smo	Ptch1	G3GZ55	G3IJP5	Smoothened-like; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein patched-like 1.	0.998