STRINGSTRING
Fgf1 Fgf1 Fmn1 Fmn1 I79_010448 I79_010448 Hnf1b Hnf1b I79_023900 I79_023900 I79_024203 I79_024203 I79_024202 I79_024202 Sall1 Sall1 I79_006364 I79_006364 Kif26b Kif26b
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
Fmn1Formin-1. (644 aa)
I79_010448Formin-1. (1049 aa)
Hnf1bHepatocyte nuclear factor 1-beta. (593 aa)
I79_023900Leucine zipper putative tumor suppressor 2. (449 aa)
I79_024203Sal-like protein 1. (121 aa)
I79_024202Sal-like protein 1. (825 aa)
Sall1Sal-like protein 1. (1294 aa)
I79_006364Kinesin-like protein KIF26B. (158 aa)
Kif26bKinesin-like protein KIF26B. (189 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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