(10 nodes) Regulation of branching involved in salivary gland morphogenesis network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	I79_004031	Fibroblast growth factor receptor. (731 aa)
	Snai2	Zinc finger protein SNAI2-like protein. (268 aa)
	Btbd7	BTB/POZ domain-containing protein 7. (399 aa)
	I79_014492	BTB/POZ domain-containing protein 7. (258 aa)
	Tnf	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (234 aa)
	Fgf7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
	Hgf	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (728 aa)
	Cdh1	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. (744 aa)
	Ntn4	Netrin-4. (574 aa)
	I79_007063	Hepatocyte growth factor receptor. (1222 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Btbd7	I79_014492	G3HU83	G3HU84	BTB/POZ domain-containing protein 7.	BTB/POZ domain-containing protein 7.	0.899
Cdh1	I79_004031	G3HKU8	G3H1K2	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins.	Fibroblast growth factor receptor.	0.499
Cdh1	I79_007063	G3HKU8	G3H9I9	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins.	Hepatocyte growth factor receptor.	0.626
Cdh1	Snai2	G3HKU8	G3HQT7	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins.	Zinc finger protein SNAI2-like protein.	0.635
Fgf7	Hgf	G3IAS3	G3HPQ5	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.786
Fgf7	I79_004031	G3IAS3	G3H1K2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor.	0.925
Fgf7	I79_007063	G3IAS3	G3H9I9	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Hepatocyte growth factor receptor.	0.416
Fgf7	Tnf	G3IAS3	G3HZG9	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.436
Hgf	Fgf7	G3HPQ5	G3IAS3	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.786
Hgf	I79_004031	G3HPQ5	G3H1K2	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Fibroblast growth factor receptor.	0.482
Hgf	I79_007063	G3HPQ5	G3H9I9	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Hepatocyte growth factor receptor.	0.990
I79_004031	Cdh1	G3H1K2	G3HKU8	Fibroblast growth factor receptor.	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins.	0.499
I79_004031	Fgf7	G3H1K2	G3IAS3	Fibroblast growth factor receptor.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.925
I79_004031	Hgf	G3H1K2	G3HPQ5	Fibroblast growth factor receptor.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.482
I79_007063	Cdh1	G3H9I9	G3HKU8	Hepatocyte growth factor receptor.	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins.	0.626
I79_007063	Fgf7	G3H9I9	G3IAS3	Hepatocyte growth factor receptor.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.416
I79_007063	Hgf	G3H9I9	G3HPQ5	Hepatocyte growth factor receptor.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.990
I79_007063	Tnf	G3H9I9	G3HZG9	Hepatocyte growth factor receptor.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.436
I79_014492	Btbd7	G3HU84	G3HU83	BTB/POZ domain-containing protein 7.	BTB/POZ domain-containing protein 7.	0.899
Snai2	Cdh1	G3HQT7	G3HKU8	Zinc finger protein SNAI2-like protein.	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins.	0.635