STRINGSTRING
Frs2 Frs2 Tp63 Tp63 I79_000973 I79_000973 Mmp2 Mmp2 Gli2 Gli2 I79_006254 I79_006254 I79_006225 I79_006225 Igf1 Igf1 Hoxb13 Hoxb13 I79_005358 I79_005358 Hoxd13 Hoxd13 Nog Nog Fgfr2 Fgfr2 Ar Ar Foxa1 Foxa1 I79_019663 I79_019663 I79_019286 I79_019286 Rarg Rarg Tnc Tnc Igf1r Igf1r Sfrp1 Sfrp1 Fem1b Fem1b
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Frs2Fibroblast growth factor receptor substrate 2. (509 aa)
Tp63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (642 aa)
I79_000973Transcription factor SOX-10. (360 aa)
Mmp272 kDa type IV collagenase. (662 aa)
Gli2Zinc finger protein GLI2. (1547 aa)
I79_006254Bone morphogenetic protein 4. (406 aa)
I79_006225Sonic hedgehog protein. (226 aa)
Igf1Insulin-like growth factor I. (75 aa)
Hoxb13Homeobox protein Hox-B13. (284 aa)
I79_005358Estrogen receptor beta. (58 aa)
Hoxd13Homeobox protein Hox-D13. (204 aa)
NogNoggin. (117 aa)
Fgfr2Fibroblast growth factor receptor 2. (659 aa)
ArAndrogen receptor. (517 aa)
Foxa1Hepatocyte nuclear factor 3-alpha. (434 aa)
I79_01966325-hydroxycholesterol 7-alpha-hydroxylase; Belongs to the cytochrome P450 family. (216 aa)
I79_019286Androgen receptor. (295 aa)
RargRetinoic acid receptor gamma. (458 aa)
TncTenascin. (2202 aa)
Igf1rInsulin-like growth factor 1 receptor. (191 aa)
Sfrp1Secreted frizzled-related protein 1. (104 aa)
Fem1bProtein fem-1-like B. (469 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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