(22 nodes) Mammary gland alveolus development network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Foxb1	Forkhead box protein B1. (325 aa)
	Ccnd1	G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)
	Foxf1	Forkhead box protein F1. (320 aa)
	Phb2	Prohibitin-2. (396 aa)
	I79_005331	Receptor tyrosine-protein kinase erbB-4. (480 aa)
	I79_007089	Receptor tyrosine-protein kinase erbB-4. (225 aa)
	I79_007090	Receptor tyrosine-protein kinase erbB-4. (182 aa)
	Tnfsf11	Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (199 aa)
	PRLR	Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (605 aa)
	I79_011789	DNA-binding protein inhibitor ID-2. (185 aa)
	Ddr1	Epithelial discoidin domain-containing receptor 1 isoform 1. (910 aa)
	I79_013712	Suppressor of cytokine signaling 2. (198 aa)
	Agap2	Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2. (829 aa)
	Hif1a	Hypoxia-inducible factor 1 alpha. (820 aa)
	Chuk	Inhibitor of nuclear factor kappa-B kinase subunit alpha. (647 aa)
	Tgfa	Protransforming growth factor alpha. (211 aa)
	I79_019286	Androgen receptor. (295 aa)
	Areg	Amphiregulin. (230 aa)
	I79_021564	Pro-epidermal growth factor. (699 aa)
	Ar	Androgen receptor. (517 aa)
	Tph1	Tryptophan 5-hydroxylase 1. (115 aa)
	I79_024533	Tryptophan 5-hydroxylase 1. (131 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ar	Ccnd1	G3IGU9	A5A422	Androgen receptor.	G1/S-specific cyclin-D1; Belongs to the cyclin family.	0.692
Ar	I79_019286	G3IGU9	G3I705	Androgen receptor.	Androgen receptor.	0.915
Areg	I79_005331	G3IBU4	G3H4W8	Amphiregulin.	Receptor tyrosine-protein kinase erbB-4.	0.854
Areg	I79_007089	G3IBU4	G3H9L3	Amphiregulin.	Receptor tyrosine-protein kinase erbB-4.	0.599
Areg	I79_007090	G3IBU4	G3H9L4	Amphiregulin.	Receptor tyrosine-protein kinase erbB-4.	0.599
Areg	I79_021564	G3IBU4	G3ID03	Amphiregulin.	Pro-epidermal growth factor.	0.777
Areg	Tgfa	G3IBU4	G3I6E7	Amphiregulin.	Protransforming growth factor alpha.	0.732
Ccnd1	Ar	A5A422	G3IGU9	G1/S-specific cyclin-D1; Belongs to the cyclin family.	Androgen receptor.	0.692
Ccnd1	Hif1a	A5A422	G3HZ04	G1/S-specific cyclin-D1; Belongs to the cyclin family.	Hypoxia-inducible factor 1 alpha.	0.600
Ccnd1	I79_019286	A5A422	G3I705	G1/S-specific cyclin-D1; Belongs to the cyclin family.	Androgen receptor.	0.690
Hif1a	Ccnd1	G3HZ04	A5A422	Hypoxia-inducible factor 1 alpha.	G1/S-specific cyclin-D1; Belongs to the cyclin family.	0.600
Hif1a	I79_021564	G3HZ04	G3ID03	Hypoxia-inducible factor 1 alpha.	Pro-epidermal growth factor.	0.414
I79_005331	Areg	G3H4W8	G3IBU4	Receptor tyrosine-protein kinase erbB-4.	Amphiregulin.	0.854
I79_005331	I79_007089	G3H4W8	G3H9L3	Receptor tyrosine-protein kinase erbB-4.	Receptor tyrosine-protein kinase erbB-4.	0.899
I79_005331	I79_007090	G3H4W8	G3H9L4	Receptor tyrosine-protein kinase erbB-4.	Receptor tyrosine-protein kinase erbB-4.	0.899
I79_005331	I79_021564	G3H4W8	G3ID03	Receptor tyrosine-protein kinase erbB-4.	Pro-epidermal growth factor.	0.822
I79_005331	Tgfa	G3H4W8	G3I6E7	Receptor tyrosine-protein kinase erbB-4.	Protransforming growth factor alpha.	0.893
I79_007089	Areg	G3H9L3	G3IBU4	Receptor tyrosine-protein kinase erbB-4.	Amphiregulin.	0.599
I79_007089	I79_005331	G3H9L3	G3H4W8	Receptor tyrosine-protein kinase erbB-4.	Receptor tyrosine-protein kinase erbB-4.	0.899
I79_007089	I79_007090	G3H9L3	G3H9L4	Receptor tyrosine-protein kinase erbB-4.	Receptor tyrosine-protein kinase erbB-4.	0.931