(8 nodes) Blood vessel endothelial cell differentiation network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Hey2	Hairy/enhancer-of-split related with YRPW motif protein 2. (276 aa)
	Rbpj	Recombining binding protein suppressor of hairless-like protein. (486 aa)
	I79_022034	Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1150 aa)
	Prox1	Prospero homeobox protein 1. (738 aa)
	Tmem100	Transmembrane protein 100. (134 aa)
	Ccm2	Malcavernin. (454 aa)
	Dll1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (741 aa)
	I79_015033	Hairy/enhancer-of-split related with YRPW motif protein 1. (199 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Dll1	Hey2	G3HNT7	G3IB43	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Hairy/enhancer-of-split related with YRPW motif protein 2.	0.540
Dll1	I79_015033	G3HNT7	G3HVP3	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Hairy/enhancer-of-split related with YRPW motif protein 1.	0.560
Dll1	Rbpj	G3HNT7	G3ICG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Recombining binding protein suppressor of hairless-like protein.	0.829
Hey2	Dll1	G3IB43	G3HNT7	Hairy/enhancer-of-split related with YRPW motif protein 2.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.540
Hey2	I79_015033	G3IB43	G3HVP3	Hairy/enhancer-of-split related with YRPW motif protein 2.	Hairy/enhancer-of-split related with YRPW motif protein 1.	0.668
Hey2	Rbpj	G3IB43	G3ICG1	Hairy/enhancer-of-split related with YRPW motif protein 2.	Recombining binding protein suppressor of hairless-like protein.	0.642
I79_015033	Dll1	G3HVP3	G3HNT7	Hairy/enhancer-of-split related with YRPW motif protein 1.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.560
I79_015033	Hey2	G3HVP3	G3IB43	Hairy/enhancer-of-split related with YRPW motif protein 1.	Hairy/enhancer-of-split related with YRPW motif protein 2.	0.668
I79_015033	Rbpj	G3HVP3	G3ICG1	Hairy/enhancer-of-split related with YRPW motif protein 1.	Recombining binding protein suppressor of hairless-like protein.	0.584
Rbpj	Dll1	G3ICG1	G3HNT7	Recombining binding protein suppressor of hairless-like protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.829
Rbpj	Hey2	G3ICG1	G3IB43	Recombining binding protein suppressor of hairless-like protein.	Hairy/enhancer-of-split related with YRPW motif protein 2.	0.642
Rbpj	I79_015033	G3ICG1	G3HVP3	Recombining binding protein suppressor of hairless-like protein.	Hairy/enhancer-of-split related with YRPW motif protein 1.	0.584