(18 nodes) Negative regulation of miRNA-mediated gene silencing network (Cricetulus griseus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	Tgfb1	Transforming growth factor beta-1. (237 aa)
	Bcdin3d	Putative methyltransferase BCDIN3D. (273 aa)
	Ncor1	Nuclear receptor corepressor 1. (1591 aa)
	I79_023475	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform. (81 aa)
	I79_001744	Nuclear receptor corepressor 1. (680 aa)
	Zmpste24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
	Zc3h12a	Ribonuclease ZC3H12A. (577 aa)
	I79_010330	Hepatocyte nuclear factor 1-alpha. (668 aa)
	Stat3	Signal transducer and activator of transcription. (770 aa)
	Zc3h10	Zinc finger CCCH domain-containing protein 10. (435 aa)
	I79_013537	ELAV-like protein; Belongs to the RRM elav family. (335 aa)
	Mecp2	Methyl-CpG-binding protein 2. (203 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa)
	I79_015109	Interleukin-6. (174 aa)
	Ncor2	Nuclear receptor corepressor 2. (2530 aa)
	Tnf	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (234 aa)
	Dnd1	Dead end protein-like 1. (352 aa)
	I79_022515	Serine/threonine-protein phosphatase. (325 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bcdin3d	Zc3h10	G3IFS7	G3HRJ9	Putative methyltransferase BCDIN3D.	Zinc finger CCCH domain-containing protein 10.	0.594
I79_001744	Mecp2	G3GVK5	G3HSV2	Nuclear receptor corepressor 1.	Methyl-CpG-binding protein 2.	0.649
I79_001744	Ncor1	G3GVK5	G3GVK4	Nuclear receptor corepressor 1.	Nuclear receptor corepressor 1.	0.939
I79_001744	Ncor2	G3GVK5	G3HX52	Nuclear receptor corepressor 1.	Nuclear receptor corepressor 2.	0.811
I79_001744	PPARG	G3GVK5	G3HVG0	Nuclear receptor corepressor 1.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.943
I79_015109	PPARG	G3HVW6	G3HVG0	Interleukin-6.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.708
I79_015109	Stat3	G3HVW6	G3HLW9	Interleukin-6.	Signal transducer and activator of transcription.	0.912
I79_015109	Tgfb1	G3HVW6	G3IA12	Interleukin-6.	Transforming growth factor beta-1.	0.785
I79_015109	Tnf	G3HVW6	G3HZG9	Interleukin-6.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.772
I79_015109	Zc3h12a	G3HVW6	G3HE23	Interleukin-6.	Ribonuclease ZC3H12A.	0.425
Mecp2	I79_001744	G3HSV2	G3GVK5	Methyl-CpG-binding protein 2.	Nuclear receptor corepressor 1.	0.649
Mecp2	Ncor1	G3HSV2	G3GVK4	Methyl-CpG-binding protein 2.	Nuclear receptor corepressor 1.	0.649
Mecp2	Ncor2	G3HSV2	G3HX52	Methyl-CpG-binding protein 2.	Nuclear receptor corepressor 2.	0.734
Mecp2	PPARG	G3HSV2	G3HVG0	Methyl-CpG-binding protein 2.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.531
Ncor1	I79_001744	G3GVK4	G3GVK5	Nuclear receptor corepressor 1.	Nuclear receptor corepressor 1.	0.939
Ncor1	Mecp2	G3GVK4	G3HSV2	Nuclear receptor corepressor 1.	Methyl-CpG-binding protein 2.	0.649
Ncor1	Ncor2	G3GVK4	G3HX52	Nuclear receptor corepressor 1.	Nuclear receptor corepressor 2.	0.811
Ncor1	PPARG	G3GVK4	G3HVG0	Nuclear receptor corepressor 1.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.943
Ncor2	I79_001744	G3HX52	G3GVK5	Nuclear receptor corepressor 2.	Nuclear receptor corepressor 1.	0.811
Ncor2	Mecp2	G3HX52	G3HSV2	Nuclear receptor corepressor 2.	Methyl-CpG-binding protein 2.	0.734