(56 nodes) Coronary vasculature development network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Tab1	Mitogen-activated protein kinase kinase kinase 7-interacting protein 1. (336 aa)
	Tmem145	Multiple epidermal growth factor-like domains 8. (2639 aa)
	Pde2a	cGMP-dependent 3',5'-cyclic phosphodiesterase; Belongs to the cyclic nucleotide phosphodiesterase family. (216 aa)
	Nrp1	Neuropilin; Belongs to the neuropilin family. (923 aa)
	Srf	Serum response factor. (361 aa)
	I79_016223	Tyrosine-protein kinase-like 7. (98 aa)
	I79_021177	Kinesin-like protein KIF7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1191 aa)
	I79_022305	Proprotein convertase subtilisin/kexin type 5. (170 aa)
	Prickle1	Prickle-like protein 1. (619 aa)
	Mmp21	Matrix metalloproteinase-21. (567 aa)
	I79_023125	Proprotein convertase subtilisin/kexin type 5. (661 aa)
	I79_023816	Proprotein convertase subtilisin/kexin type 5. (306 aa)
	I79_024810	Cryptic protein. (69 aa)
	I79_024932	Dynactin subunit 5. (82 aa)
	Prdm1	PR domain zinc finger protein 1. (825 aa)
	I79_013660	Beta-type platelet-derived growth factor receptor. (454 aa)
	Lrp1	Prolow-density lipoprotein receptor-related protein 1. (2217 aa)
	Pdgfrb	Beta-type platelet-derived growth factor receptor. (528 aa)
	I79_013668	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1. (809 aa)
	Zbtb14	Zinc finger protein 161. (449 aa)
	Plxnd1	Plexin-D1. (612 aa)
	Aplnr	Apelin receptor; Belongs to the G-protein coupled receptor 1 family. (377 aa)
	Setd2	Histone-lysine N-methyltransferase SETD2. (2412 aa)
	Cplane1	Uncharacterized protein C5orf42. (563 aa)
	I79_010954	Uncharacterized protein C5orf42. (531 aa)
	Spred1	Sprouty-related, EVH1 domain-containing protein 1. (370 aa)
	I79_010159	Roundabout-like 1. (1362 aa)
	Robo1	Roundabout-like 1. (129 aa)
	I79_009708	Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (332 aa)
	I79_009100	Latent-transforming growth factor beta-binding protein 1. (1194 aa)
	I79_009030	T-box transcription factor TBX1. (293 aa)
	Tgfbr3	TGF-beta receptor type III. (849 aa)
	Smad6	Mothers against decapentaplegic-like 6. (174 aa)
	I79_006745	Mothers against decapentaplegic-like 6. (71 aa)
	Tgfbr1	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (401 aa)
	I79_006254	Bone morphogenetic protein 4. (406 aa)
	I79_005962	Zinc finger protein 161-like. (240 aa)
	I79_005867	Dynamin; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (885 aa)
	Smarca4	Putative global transcription activator SNF2L4. (1614 aa)
	Myh10	Myosin-10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1976 aa)
	Snx17	Sorting nexin-17. (470 aa)
	I79_001475	Cytoplasmic dynein 2 heavy chain 1. (1690 aa)
	Dync2h1	Cytoplasmic dynein 2 heavy chain 1. (117 aa)
	I79_001239	Low-density lipoprotein receptor-related protein 2. (4664 aa)
	I79_019934	Mitogen-activated protein kinase kinase kinase 7-interacting protein 1. (263 aa)
	Ap2b1	AP-2 complex subunit beta. (490 aa)
	Hey2	Hairy/enhancer-of-split related with YRPW motif protein 2. (276 aa)
	Cntrl	Centriolin. (1787 aa)
	Adamts6	A disintegrin and metalloproteinase with thrombospondin motifs 6. (1102 aa)
	Sufu	Suppressor of fused-like. (266 aa)
	Vegfb	Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (150 aa)
	Arid2	AT-rich interactive domain-containing protein 2. (1284 aa)
	I79_019340	Suppressor of fused-like. (144 aa)
	I79_019293	Protein fuzzy-like. (60 aa)
	Fuz	Protein fuzzy-like. (365 aa)
	Sgcd	Delta-sarcoglycan. (140 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Adamts6	I79_009100	G3HXI3	G3HEV3	A disintegrin and metalloproteinase with thrombospondin motifs 6.	Latent-transforming growth factor beta-binding protein 1.	0.470
Ap2b1	I79_001239	G3I8B9	G3GU85	AP-2 complex subunit beta.	Low-density lipoprotein receptor-related protein 2.	0.400
Ap2b1	I79_005867	G3I8B9	G3H6B2	AP-2 complex subunit beta.	Dynamin; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.529
Arid2	Smarca4	G3I803	G3H6A7	AT-rich interactive domain-containing protein 2.	Putative global transcription activator SNF2L4.	0.986
Cplane1	I79_010954	G3HJV3	G3HJV2	Uncharacterized protein C5orf42.	Uncharacterized protein C5orf42.	0.813
Dync2h1	I79_001475	G3GUU9	G3GUV0	Cytoplasmic dynein 2 heavy chain 1.	Cytoplasmic dynein 2 heavy chain 1.	0.913
Dync2h1	I79_021177	G3GUU9	G3IBZ1	Cytoplasmic dynein 2 heavy chain 1.	Kinesin-like protein KIF7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.411
Dync2h1	I79_024932	G3GUU9	G3IM06	Cytoplasmic dynein 2 heavy chain 1.	Dynactin subunit 5.	0.480
I79_001239	Ap2b1	G3GU85	G3I8B9	Low-density lipoprotein receptor-related protein 2.	AP-2 complex subunit beta.	0.400
I79_001475	Dync2h1	G3GUV0	G3GUU9	Cytoplasmic dynein 2 heavy chain 1.	Cytoplasmic dynein 2 heavy chain 1.	0.913
I79_001475	I79_021177	G3GUV0	G3IBZ1	Cytoplasmic dynein 2 heavy chain 1.	Kinesin-like protein KIF7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.411
I79_001475	I79_024932	G3GUV0	G3IM06	Cytoplasmic dynein 2 heavy chain 1.	Dynactin subunit 5.	0.480
I79_005867	Ap2b1	G3H6B2	G3I8B9	Dynamin; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	AP-2 complex subunit beta.	0.529
I79_006254	I79_006745	G3H7C4	G3H8N7	Bone morphogenetic protein 4.	Mothers against decapentaplegic-like 6.	0.661
I79_006254	I79_009708	G3H7C4	G3HGH9	Bone morphogenetic protein 4.	Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.621
I79_006254	Prdm1	G3H7C4	G3HVR3	Bone morphogenetic protein 4.	PR domain zinc finger protein 1.	0.536
I79_006254	Smad6	G3H7C4	G3H8N8	Bone morphogenetic protein 4.	Mothers against decapentaplegic-like 6.	0.661
I79_006254	Tgfbr1	G3H7C4	G3H7H0	Bone morphogenetic protein 4.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.793
I79_006254	Tgfbr3	G3H7C4	G3HEB6	Bone morphogenetic protein 4.	TGF-beta receptor type III.	0.434
I79_006745	I79_006254	G3H8N7	G3H7C4	Mothers against decapentaplegic-like 6.	Bone morphogenetic protein 4.	0.661