STRINGSTRING
Alox5 Alox5 I79_022255 I79_022255 Cldn19 Cldn19 I79_022663 I79_022663 Anxa2 Anxa2 I79_023724 I79_023724 Abat Abat I79_002178 I79_002178 Alox12 Alox12 Gp1ba Gp1ba Pros1 Pros1 F2 F2 Phldb2 Phldb2 I79_003858 I79_003858 Tnf Tnf Gja1 Gja1 Serpine2 Serpine2 I79_025002 I79_025002 C1qtnf6 C1qtnf6 CgPICR_017246 CgPICR_017246 Tspan8 Tspan8 I79_004757 I79_004757 Clasp2 Clasp2 Sh2b3 Sh2b3 I79_003896 I79_003896 Clasp1 Clasp1 I79_003860 I79_003860 Prkcd Prkcd Cd9 Cd9 I79_000592 I79_000592 I79_000272 I79_000272 Hrg Hrg Kng1 Kng1 Crk Crk Adtrp Adtrp Serping1 Serping1 Apoe Apoe I79_011219 I79_011219 Mmrn1 Mmrn1 Wnt4 Wnt4 Cd109 Cd109 I79_009796 I79_009796 I79_007297 I79_007297 Serpine1 Serpine1 I79_006922 I79_006922 Smad3 Smad3 I79_006462 I79_006462 MED4 MED4 Fgb Fgb Fga Fga Pdgfra Pdgfra I79_024807 I79_024807 Apoh Apoh I79_017352 I79_017352 Pdgfb Pdgfb I79_017861 I79_017861 I79_018586 I79_018586 Anxa5 Anxa5 I79_020737 I79_020737 Cd34 Cd34
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Alox5Arachidonate 5-lipoxygenase. (674 aa)
I79_022255Adherens junction-associated protein 1. (281 aa)
Cldn19Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
I79_022663Ubiquitin-associated and SH3 domain-containing protein B. (85 aa)
Anxa2Annexin. (244 aa)
I79_023724Adherens junction-associated protein 1. (134 aa)
Abat4-aminobutyrate aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (455 aa)
I79_002178Urokinase-type plasminogen activator; Belongs to the peptidase S1 family. (397 aa)
Alox12Arachidonate 12-lipoxygenase, 12S-type. (553 aa)
Gp1baPlatelet glycoprotein Ib alpha chain. (446 aa)
Pros1Vitamin K-dependent protein S. (153 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (618 aa)
Phldb2Pleckstrin-likey-like domain family B member 2. (1249 aa)
I79_003858CLIP-associating protein 1. (157 aa)
TnfTumor necrosis factor; Belongs to the tumor necrosis factor family. (234 aa)
Gja1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa)
Serpine2Glia-derived nexin; Belongs to the serpin family. (189 aa)
I79_025002Ubiquitin-associated and SH3 domain-containing protein B. (201 aa)
C1qtnf6Complement C1q tumor necrosis factor-related protein 6. (266 aa)
CgPICR_017246Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (219 aa)
Tspan8Tetraspanin-8; Belongs to the tetraspanin (TM4SF) family. (95 aa)
I79_004757Complement C1q tumor necrosis factor-related protein 1. (314 aa)
Clasp2CLIP-associating protein 2. (842 aa)
Sh2b3SH2B adapter protein 3. (364 aa)
I79_003896Coagulation factor XII; Belongs to the peptidase S1 family. (560 aa)
Clasp1CLIP-associating protein 1. (751 aa)
I79_003860CLIP-associating protein 1. (341 aa)
PrkcdNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (437 aa)
Cd9Tetraspanin. (159 aa)
I79_000592Peripheral plasma membrane protein CASK; Belongs to the MAGUK family. (742 aa)
I79_000272WAP four-disulfide core domain protein 1. (275 aa)
HrgKininogen-1. (574 aa)
Kng1Kininogen-1-like protein. (136 aa)
CrkProto-oncogene C-crk. (327 aa)
AdtrpUncharacterized protein C6orf105-like. (148 aa)
Serping1Plasma protease C1 inhibitor; Belongs to the serpin family. (177 aa)
ApoeApolipoprotein E. (313 aa)
I79_011219Vitamin K-dependent protein C. (381 aa)
Mmrn1Multimerin-1. (802 aa)
Wnt4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (288 aa)
Cd109CD109 antigen. (1443 aa)
I79_009796Plasminogen; Belongs to the peptidase S1 family. Plasminogen subfamily. (697 aa)
I79_007297Plasminogen activator inhibitor 1; Belongs to the serpin family. (108 aa)
Serpine1Plasminogen activator inhibitor 1; Belongs to the serpin family. (270 aa)
I79_006922A disintegrin and metalloproteinase with thrombospondin motifs 18. (976 aa)
Smad3Mothers against decapentaplegic homolog. (363 aa)
I79_006462cGMP-dependent protein kinase 1, beta isozyme; Belongs to the protein kinase superfamily. (227 aa)
MED4Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (104 aa)
FgbFibrinogen beta chain. (407 aa)
FgaFibrinogen alpha chain. (1209 aa)
PdgfraPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1082 aa)
I79_024807Protein FAM19A5. (87 aa)
ApohBeta-2-glycoprotein 1. (577 aa)
I79_017352ATP-binding cassette transporter sub-family C member 8. (2352 aa)
PdgfbPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (205 aa)
I79_017861Solute carrier family 12 member 2. (706 aa)
I79_018586Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN. (345 aa)
Anxa5Annexin. (321 aa)
I79_020737Platelet glycoprotein V. (355 aa)
Cd34Hematopoietic progenitor cell antigen CD34. (383 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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