STRINGSTRING
I79_012815 I79_012815 I79_020248 I79_020248 Tshz1 Tshz1 I79_019127 I79_019127 I79_017833 I79_017833 Mmp25 Mmp25 Wnt11 Wnt11 Smad4 Smad4 I79_013178 I79_013178 Chd7 Chd7 I79_012814 I79_012814 Fzd2 Fzd2 Fzd1 Fzd1 I79_010136 I79_010136 Tgfb3 Tgfb3 Wnt8a Wnt8a I79_009030 I79_009030 Tgfbr3 Tgfbr3 Smad2 Smad2 Itgb6 Itgb6 I79_004721 I79_004721 Tgfbr2 Tgfbr2 Wnt5a Wnt5a Wnt7a Wnt7a I79_000092 I79_000092
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_012815Chromodomain-helicase-DNA-binding protein 7. (150 aa)
I79_020248Gamma-aminobutyric acid receptor subunit beta-3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (231 aa)
Tshz1Teashirt-like 1. (1087 aa)
I79_019127Integrin beta; Belongs to the integrin beta chain family. (435 aa)
I79_017833Lymphoid enhancer-binding factor 1. (276 aa)
Mmp25Matrix metalloproteinase-25. (413 aa)
Wnt11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
Smad4Mothers against decapentaplegic-like 4. (259 aa)
I79_013178Collagen alpha-2(XI) chain. (1125 aa)
Chd7Chromodomain-helicase-DNA-binding protein 7. (615 aa)
I79_012814Chromodomain-helicase-DNA-binding protein 7. (100 aa)
Fzd2Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (522 aa)
Fzd1Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (514 aa)
I79_010136Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (230 aa)
Tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
Wnt8aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (195 aa)
I79_009030T-box transcription factor TBX1. (293 aa)
Tgfbr3TGF-beta receptor type III. (849 aa)
Smad2Mothers against decapentaplegic homolog. (467 aa)
Itgb6Integrin beta; Belongs to the integrin beta chain family. (792 aa)
I79_004721Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1234 aa)
Tgfbr2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
Wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
Wnt7aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (282 aa)
I79_000092Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.