STRINGSTRING
Guca1b Guca1b I79_012722 I79_012722 Apoc2 Apoc2 Apoe Apoe Mapk9 Mapk9 Akt2 Akt2 Psen1 Psen1 I79_012144 I79_012144 App App Gck Gck Stat3 Stat3 Kat2a Kat2a Abcg1 Abcg1 P2ry1 P2ry1 I79_011304 I79_011304 Scap Scap Ppp4r3b Ppp4r3b I79_010863 I79_010863 Fabp1 Fabp1 I79_010620 I79_010620 Wnt4 Wnt4 I79_010458 I79_010458 I79_010330 I79_010330 I79_010155 I79_010155 Prkaa1 Prkaa1 Ntsr1 Ntsr1 I79_009834 I79_009834 Clybl Clybl I79_009790 I79_009790 I79_009443 I79_009443 Stk11 Stk11 Comt Comt Fgf1 Fgf1 Bcl2l1 Bcl2l1 C1qtnf2 C1qtnf2 Gpld1 Gpld1 Bmp6 Bmp6 Cyp7a1 Cyp7a1 Guca2a Guca2a I79_008252 I79_008252 I79_008173 I79_008173 I79_007989 I79_007989 I79_007693 I79_007693 Sirt1 Sirt1 I79_007261 I79_007261 I79_007247 I79_007247 Avpr1a Avpr1a I79_006470 I79_006470 Ghsr Ghsr Igf1 Igf1 LHCGR LHCGR Rgn Rgn Akt1 Akt1 I79_004285 I79_004285 Ptafr Ptafr Star Star Zbtb20 Zbtb20 Nr1h3 Nr1h3 Dyrk2 Dyrk2 Src Src Bend3 Bend3 Agt Agt Ptgs2 Ptgs2 Pla2g4a Pla2g4a Scp2 Scp2 Plcd1 Plcd1 Prkce Prkce I79_001592 I79_001592 Slc25a12 Slc25a12 Nos1 Nos1 Lyrm9 Lyrm9 I79_000983 I79_000983 Mid1ip1 Mid1ip1 Mlycd Mlycd CgPICR_005189 CgPICR_005189 COX2 COX2 I79_025745 I79_025745 Myc Myc Guca2b Guca2b I79_025689 I79_025689 Cpt1a Cpt1a Map2k1 Map2k1 Pid1 Pid1 Arpp19 Arpp19 Ncs1 Ncs1 Irs2 Irs2 Tcf7l2 Tcf7l2 Ddb1 Ddb1 Abcd2 Abcd2 P2ry6 P2ry6 Ppara Ppara I79_022390 I79_022390 I79_022367 I79_022367 Irs1 Irs1 I79_021679 I79_021679 Wdr5 Wdr5 I79_021405 I79_021405 I79_021093 I79_021093 TAZ TAZ I79_020783 I79_020783 I79_020647 I79_020647 I79_019630 I79_019630 I79_019629 I79_019629 I79_019626 I79_019626 I79_019625 I79_019625 Apoa5 Apoa5 CgPICR_005982 CgPICR_005982 Apoa1 Apoa1 Nr1h2 Nr1h2 Lpgat1 Lpgat1 Nr1d1 Nr1d1 Anxa1 Anxa1 I79_018763 I79_018763 I79_018762 I79_018762 I79_018761 I79_018761 ELOVL5 ELOVL5 Ndufc2 Ndufc2 I79_018654 I79_018654 Actn3 Actn3 Htr2a Htr2a I79_018131 I79_018131 Ppp4r3a Ppp4r3a Nnmt Nnmt Pla2g3 Pla2g3 IL1B IL1B Hnf4a Hnf4a I79_016797 I79_016797 Pth Pth Foxo1 Foxo1 Tnf Tnf Hif1a Hif1a Adipoq Adipoq I79_015916 I79_015916 I79_015895 I79_015895 Gpd1 Gpd1 Rdh10 Rdh10 Ppargc1a Ppargc1a Insr Insr Dgat1 Dgat1 Gpt Gpt I79_015045 I79_015045 PPARG PPARG Dgat2 Dgat2 Gper1 Gper1 Epm2aip1 Epm2aip1 I79_013971 I79_013971 Cd74 Cd74 Ppard Ppard I79_013437 I79_013437 Guca1a Guca1a
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Guca1bGuanylyl cyclase-activating protein 2. (201 aa)
I79_012722Major urinary protein 5; Belongs to the calycin superfamily. Lipocalin family. (153 aa)
Apoc2Apolipoprotein C-II. (100 aa)
ApoeApolipoprotein E. (313 aa)
Mapk9Mitogen-activated protein kinase 9. (303 aa)
Akt2Non-specific serine/threonine protein kinase. (200 aa)
Psen1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
I79_012144Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family. (2171 aa)
AppAmyloid beta A4 protein. (433 aa)
GckPhosphotransferase. (465 aa)
Stat3Signal transducer and activator of transcription. (770 aa)
Kat2aHistone acetyltransferase KAT2A. (663 aa)
Abcg1ATP-binding cassette sub-family G member 1. (647 aa)
P2ry1p2Y purinoceptor 1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
I79_011304Parathyroid hormone/parathyroid hormone-related peptide receptor; Belongs to the G-protein coupled receptor 2 family. (626 aa)
ScapSterol regulatory element-binding protein cleavage-activating protein. (1276 aa)
Ppp4r3bSerine/threonine-protein phosphatase 4 regulatory subunit 3B. (1364 aa)
I79_010863Pituitary adenylate cyclase-activating polypeptide type I receptor; Belongs to the G-protein coupled receptor 2 family. (533 aa)
Fabp1Fatty acid-binding protein, liver. (149 aa)
I79_010620Alpha-synuclein; Belongs to the synuclein family. (166 aa)
Wnt4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (288 aa)
I79_010458Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (451 aa)
I79_010330Hepatocyte nuclear factor 1-alpha. (668 aa)
I79_010155Sterol regulatory element-binding protein 1. (1050 aa)
Prkaa1Non-specific serine/threonine protein kinase. (477 aa)
Ntsr1Neurotensin receptor type 1; Belongs to the G-protein coupled receptor 1 family. (394 aa)
I79_009834Disabled-like 2. (705 aa)
ClyblCitrate lyase subunit beta-like protein, mitochondrial. (315 aa)
I79_009790MAS proto-oncogene; Belongs to the G-protein coupled receptor 1 family. (324 aa)
I79_009443Steroid hormone receptor ERR2. (475 aa)
Stk11Serine/threonine-protein kinase 11. (505 aa)
ComtCatechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. (265 aa)
Fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
Bcl2l1Bcl-2-like protein 1. (233 aa)
C1qtnf2Complement C1q tumor necrosis factor-related protein 2. (285 aa)
Gpld1Phosphatidylinositol-glycan-specific phospholipase D. (778 aa)
Bmp6Bone morphogenetic protein 6. (296 aa)
Cyp7a1Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (360 aa)
Guca2aGuanylin. (138 aa)
I79_008252Guanylate cyclase activator 2B. (104 aa)
I79_008173Perilipin; Belongs to the perilipin family. (419 aa)
I79_007989Farnesyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. (375 aa)
I79_007693Nitric oxide synthase; Produces nitric oxide (NO). (1129 aa)
Sirt1NAD-dependent deacetylase sirtuin-1. (554 aa)
I79_007261NADPH--cytochrome P450 reductase. (522 aa)
I79_007247Williams-Beuren syndrome chromosomal region 14 protein-like. (709 aa)
Avpr1aVasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (423 aa)
I79_006470Natural killer cell receptor 2B4. (280 aa)
GhsrGrowth hormone secretagogue receptor type 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
Igf1Insulin-like growth factor I. (75 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (688 aa)
RgnRegucalcin. (265 aa)
Akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
I79_004285p2X purinoceptor 7. (805 aa)
PtafrPlatelet-activating factor receptor; Belongs to the G-protein coupled receptor 1 family. (341 aa)
StarSteroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (279 aa)
Zbtb20Zinc finger and BTB domain-containing protein 20. (741 aa)
Nr1h3Oxysterols receptor LXR-alpha. (402 aa)
Dyrk2Dual specificity tyrosine-phosphorylation-regulated kinase 2. (528 aa)
SrcTyrosine-protein kinase. (536 aa)
Bend3BEN domain-containing protein 3. (824 aa)
AgtAngiotensinogen; Belongs to the serpin family. (477 aa)
Ptgs2Prostaglandin G/H synthase 2. (604 aa)
Pla2g4aPhospholipase A2. (749 aa)
Scp2Non-specific lipid-transfer protein; Belongs to the thiolase-like superfamily. Thiolase family. (547 aa)
Plcd1Phosphoinositide phospholipase C. (782 aa)
PrkceProtein kinase C epsilon type. (137 aa)
I79_001592Protein kinase C epsilon type. (163 aa)
Slc25a12Calcium-binding mitochondrial carrier protein Aralar1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (646 aa)
Nos1Nitric oxide synthase; Produces nitric oxide (NO). (1413 aa)
Lyrm9Nitric oxide synthase; Produces nitric oxide (NO); Belongs to the complex I LYR family. (1115 aa)
I79_000983Non-specific serine/threonine protein kinase. (747 aa)
Mid1ip1Mid1-interacting protein 1. (183 aa)
MlycdMalonyl-CoA decarboxylase, mitochondrial. (190 aa)
CgPICR_005189cAMP-regulated phosphoprotein 19; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (96 aa)
COX2Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. (227 aa)
I79_025745Nuclear receptor subfamily 1 group D member 1. (226 aa)
MycMyc proto-oncogene protein. (281 aa)
Guca2bGuanylate cyclase activator 2B. (107 aa)
I79_025689Epididymal-specific lipocalin-13; Belongs to the calycin superfamily. Lipocalin family. (158 aa)
Cpt1aCarnitine O-palmitoyltransferase 1, liver isoform. (127 aa)
Map2k1Dual specificity mitogen-activated protein kinase kinase 1. (101 aa)
Pid1PTB-containing, cubilin and LRP1-interacting protein. (159 aa)
Arpp19cAMP-regulated phosphoprotein 19; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (112 aa)
Ncs1Neuronal calcium sensor 1. (70 aa)
Irs2Insulin receptor substrate 2. (465 aa)
Tcf7l2Transcription factor 7-like 1. (73 aa)
Ddb1DNA damage-binding protein 1. (1140 aa)
Abcd2ATP-binding cassette sub-family D member 2. (741 aa)
P2ry6p2Y purinoceptor 6. (328 aa)
PparaPeroxisome proliferator-activated receptor alpha. (393 aa)
I79_022390Peroxisome proliferator-activated receptor alpha. (110 aa)
I79_022367Nucleobindin-2. (420 aa)
Irs1Insulin receptor substrate 1. (1233 aa)
I79_021679POU domain protein. (218 aa)
Wdr5WD repeat-containing protein 5. (334 aa)
I79_021405Anion exchange protein. (927 aa)
I79_021093Sterol regulatory element-binding protein 2. (2034 aa)
TAZTafazzin family protein; Some isoforms may be involved in cardiolipin metabolism. (263 aa)
I79_020783Transcription factor 7-like 2. (451 aa)
I79_020647Protein FAM48A. (330 aa)
I79_019630Liver carboxylesterase 1; Belongs to the type-B carboxylesterase/lipase family. (765 aa)
I79_019629Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (564 aa)
I79_019626Liver carboxylesterase 4. (105 aa)
I79_019625Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (514 aa)
Apoa5Apolipoprotein A-V. (363 aa)
CgPICR_005982Apolipoprotein A-IV. (230 aa)
Apoa1Apolipoprotein A-I. (264 aa)
Nr1h2Oxysterols receptor LXR-beta. (445 aa)
Lpgat1Acyl-CoA:lysophosphatidylglycerol acyltransferase 1. (351 aa)
Nr1d1Nuclear receptor subfamily 1 group D member 1. (508 aa)
Anxa1Annexin. (346 aa)
I79_018763Liver carboxylesterase 4. (393 aa)
I79_018762Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (370 aa)
I79_018761Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (448 aa)
ELOVL5Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] (299 aa)
Ndufc2NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (120 aa)
I79_018654Carnitine O-palmitoyltransferase 1, liver isoform. (467 aa)
Actn3Alpha-actinin-3. (900 aa)
Htr2a5-hydroxytryptamine receptor 2A. (264 aa)
I79_0181315-hydroxytryptamine receptor 2A; Belongs to the G-protein coupled receptor 1 family. (237 aa)
Ppp4r3aSerine/threonine-protein phosphatase 4 regulatory subunit 3A. (400 aa)
NnmtNicotinamide N-methyltransferase. (265 aa)
Pla2g3Group 3 secretory phospholipase A2. (398 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa)
Hnf4aHepatocyte nuclear factor 4-alpha. (464 aa)
I79_016797Dual specificity mitogen-activated protein kinase kinase 1. (129 aa)
PthParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (114 aa)
Foxo1Forkhead box protein O1. (469 aa)
TnfTumor necrosis factor; Belongs to the tumor necrosis factor family. (234 aa)
Hif1aHypoxia-inducible factor 1 alpha. (820 aa)
AdipoqAdiponectin. (248 aa)
I79_015916Insulin-like growth factor II. (155 aa)
I79_015895Sorbin and SH3 domain-containing protein 1. (852 aa)
Gpd1Glycerol-3-phosphate dehydrogenase [NAD(+)]. (443 aa)
Rdh10Retinol dehydrogenase 10. (65 aa)
Ppargc1aPeroxisome proliferator-activated receptor gamma coactivator 1-alpha. (894 aa)
InsrInsulin receptor. (114 aa)
Dgat1Diacylglycerol O-acyltransferase 1; Belongs to the membrane-bound acyltransferase family. (327 aa)
GptAlanine aminotransferase 1. (481 aa)
I79_015045MAS proto-oncogene. (172 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa)
Dgat2Diacylglycerol O-acyltransferase 2. (388 aa)
Gper1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (371 aa)
Epm2aip1EPM2A-interacting protein 1. (606 aa)
I79_013971ATP-binding cassette sub-family D member 1. (694 aa)
Cd74H-2 class II histocompatibility antigen gamma chain. (329 aa)
PpardPeroxisome proliferator-activated receptor delta. (440 aa)
I79_013437Nuclear receptor subfamily 4 group A member 3. (598 aa)
Guca1aGuanylyl cyclase-activating protein 1. (201 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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