STRINGSTRING
I79_008810 I79_008810 Wdtc1 Wdtc1 Hdac4 Hdac4 Adipoq Adipoq I79_015980 I79_015980 Tspo Tspo I79_015806 I79_015806 Ppargc1a Ppargc1a Dkk3 Dkk3 I79_015207 I79_015207 I79_008906 I79_008906 Plek Plek Snai1 Snai1 I79_010352 I79_010352 Wnt4 Wnt4 C1qtnf3 C1qtnf3 Slc4a1 Slc4a1 Stat3 Stat3 Brca1 Brca1 Gck Gck Mfsd2a Mfsd2a Cry1 Cry1 Apoe Apoe Etfbkmt Etfbkmt I79_012722 I79_012722 I79_012733 I79_012733 Fmo4 Fmo4 Fmo2 Fmo2 Atp2b4 Atp2b4 Ier3 Ier3 Snai2 Snai2 Git1 Git1 I79_013817 I79_013817 I79_013844 I79_013844 CgPICR_002342 CgPICR_002342 Dgat2 Dgat2 Parp1 Parp1 Prox1 Prox1 I79_000120 I79_000120 Cbfa2t3 Cbfa2t3 I79_000677 I79_000677 I79_000973 I79_000973 SIRT4 SIRT4 Slc25a12 Slc25a12 Tigar Tigar Ncor1 Ncor1 I79_001744 I79_001744 Soga1 Soga1 Acadvl Acadvl I79_003344 I79_003344 Entpd1 Entpd1 I79_003387 I79_003387 Erlin2 Erlin2 I79_015109 I79_015109 Rd3 Rd3 Akt1 Akt1 Myog Myog I79_005488 I79_005488 Insig2 Insig2 I79_025689 I79_025689 Dbi Dbi I79_006650 I79_006650 Nfkb1 Nfkb1 I79_025482 I79_025482 Pid1 Pid1 I79_024892 I79_024892 I79_024210 I79_024210 Ppara Ppara I79_022390 I79_022390 Fam3c Fam3c H671_3g10030 H671_3g10030 I79_020433 I79_020433 Slc27a4 Slc27a4 Mst1 Mst1 Hpca Hpca Fis1 Fis1 Sirt1 Sirt1 I79_007399 I79_007399 Pgp Pgp I79_007993 I79_007993 Clk2 Clk2 Sik1 Sik1 Trib3 Trib3 I79_008173 I79_008173 Rest Rest Apoc3 Apoc3 Ep300 Ep300 Actn3 Actn3 Fgf19 Fgf19 I79_018194 I79_018194 C1qtnf12 C1qtnf12 Hpcal1 Hpcal1 Serpina12 Serpina12 Erfe Erfe Ddit4 Ddit4 Dkkl1 Dkkl1 I79_016547 I79_016547 Cyp7a1 Cyp7a1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_008810Protein arginine N-methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (495 aa)
Wdtc1WD and tetratricopeptide repeats protein 1. (675 aa)
Hdac4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (966 aa)
AdipoqAdiponectin. (248 aa)
I79_015980Leptin receptor. (533 aa)
TspoTranslocator protein. (169 aa)
I79_015806Acyl-CoA-binding protein. (87 aa)
Ppargc1aPeroxisome proliferator-activated receptor gamma coactivator 1-alpha. (894 aa)
Dkk3Dickkopf-related protein 3. (348 aa)
I79_01520725-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial; Belongs to the cytochrome P450 family. (232 aa)
I79_008906Zinc finger protein Gfi-1. (333 aa)
PlekPleckstrin. (327 aa)
Snai1Zinc finger protein SNAI1-like protein. (264 aa)
I79_010352Acetyl-CoA carboxylase 2. (2287 aa)
Wnt4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (288 aa)
C1qtnf3Complement C1q tumor necrosis factor-related protein 3. (319 aa)
Slc4a1Anion exchange protein. (915 aa)
Stat3Signal transducer and activator of transcription. (770 aa)
Brca1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1790 aa)
GckPhosphotransferase. (465 aa)
Mfsd2aMajor facilitator superfamily domain-containing protein 2. (527 aa)
Cry1Cryptochrome-1. (428 aa)
ApoeApolipoprotein E. (313 aa)
EtfbkmtUPF0516 protein C12orf72-like. (126 aa)
I79_012722Major urinary protein 5; Belongs to the calycin superfamily. Lipocalin family. (153 aa)
I79_012733Flavin-containing monooxygenase. (88 aa)
Fmo4Flavin-containing monooxygenase. (367 aa)
Fmo2Flavin-containing monooxygenase. (129 aa)
Atp2b4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1189 aa)
Ier3Radiation-inducible immediate-early gene IEX-1. (160 aa)
Snai2Zinc finger protein SNAI2-like protein. (268 aa)
Git1ARF GTPase-activating protein GIT1. (809 aa)
I79_013817NAD-dependent deacetylase sirtuin-6. (334 aa)
I79_013844Caytaxin. (355 aa)
CgPICR_002342Acyl-CoA-binding protein. (87 aa)
Dgat2Diacylglycerol O-acyltransferase 2. (388 aa)
Parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (971 aa)
Prox1Prospero homeobox protein 1. (738 aa)
I79_000120Bone morphogenetic protein 5. (260 aa)
Cbfa2t3Protein CBFA2T3. (593 aa)
I79_000677Cannabinoid receptor 1; Belongs to the G-protein coupled receptor 1 family. (415 aa)
I79_000973Transcription factor SOX-10. (360 aa)
SIRT4NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (255 aa)
Slc25a12Calcium-binding mitochondrial carrier protein Aralar1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (646 aa)
TigarPutative fructose-2,6-bisphosphatase TIGAR. (266 aa)
Ncor1Nuclear receptor corepressor 1. (1591 aa)
I79_001744Nuclear receptor corepressor 1. (680 aa)
Soga1Uncharacterized protein C20orf117. (1897 aa)
AcadvlVery long-chain specific acyl-CoA dehydrogenase, mitochondrial. (652 aa)
I79_0033442-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (337 aa)
Entpd1Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. (269 aa)
I79_003387Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. (219 aa)
Erlin2Erlin-2. (339 aa)
I79_015109Interleukin-6. (174 aa)
Rd3Protein RD3. (195 aa)
Akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
MyogMyogenin. (224 aa)
I79_005488Progesterone-induced-blocking factor 1. (757 aa)
Insig2Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa)
I79_025689Epididymal-specific lipocalin-13; Belongs to the calycin superfamily. Lipocalin family. (158 aa)
DbiAcyl-CoA-binding protein. (119 aa)
I79_006650Hepatocyte growth factor-like protein. (93 aa)
Nfkb1Nuclear factor NF-kappa-B p105 subunit. (509 aa)
I79_025482Nuclear factor NF-kappa-B p105 subunit. (144 aa)
Pid1PTB-containing, cubilin and LRP1-interacting protein. (159 aa)
I79_024892Fructose-1,6-bisphosphatase 1. (66 aa)
I79_024210Nuclear protein 1. (103 aa)
PparaPeroxisome proliferator-activated receptor alpha. (393 aa)
I79_022390Peroxisome proliferator-activated receptor alpha. (110 aa)
Fam3cProtein FAM3C. (227 aa)
H671_3g10030Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. (204 aa)
I79_020433Carcinoembryonic antigen-related cell adhesion molecule 1. (155 aa)
Slc27a4Long-chain fatty acid transport protein 4. (643 aa)
Mst1Hepatocyte growth factor-like protein. (88 aa)
HpcaNeuron-specific calcium-binding protein hippocalcin. (193 aa)
Fis1Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa)
Sirt1NAD-dependent deacetylase sirtuin-1. (554 aa)
I79_007399MAM and LDL-receptor class A domain-containing protein C10orf112. (1182 aa)
PgpPhosphoglycolate phosphatase. (617 aa)
I79_007993Dual specificity protein kinase CLK2. (137 aa)
Clk2Dual specificity protein kinase CLK2. (109 aa)
Sik1Serine/threonine-protein kinase SIK1. (729 aa)
Trib3Tribbles-like 3. (353 aa)
I79_008173Perilipin; Belongs to the perilipin family. (419 aa)
RestRE1-silencing transcription factor. (1047 aa)
Apoc3Apolipoprotein C-III. (76 aa)
Ep300Histone acetyltransferase p300. (2415 aa)
Actn3Alpha-actinin-3. (900 aa)
Fgf19Fibroblast growth factor 15; Belongs to the heparin-binding growth factors family. (115 aa)
I79_018194Protein FAM132A. (127 aa)
C1qtnf12Protein FAM132A. (61 aa)
Hpcal1Hippocalcin-like protein 1. (193 aa)
Serpina12Serpin A12; Belongs to the serpin family. (414 aa)
ErfeProtein FAM132B. (344 aa)
Ddit4DNA-damage-inducible transcript 4 protein. (231 aa)
Dkkl1Dickkopf-like protein 1. (230 aa)
I79_016547DCC-interacting protein 13-beta. (634 aa)
Cyp7a1Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (360 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.