(47 nodes) Neuron cellular homeostasis network (Cricetulus griseus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	Tmem175	Transmembrane protein 175. (499 aa)
	P2ry4	p2Y purinoceptor 4-like protein; Belongs to the G-protein coupled receptor 1 family. (361 aa)
	Dctn1	Dynactin subunit 1. (559 aa)
	I79_019613	Dynactin subunit 1. (163 aa)
	Chmp2b	Charged multivesicular body protein 2b. (202 aa)
	Ncs1	Neuronal calcium sensor 1. (70 aa)
	P2ry2	p2Y purinoceptor 2; Belongs to the G-protein coupled receptor 1 family. (151 aa)
	I79_025216	Beta-hexosaminidase subunit beta. (74 aa)
	HAAO	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. (276 aa)
	I79_002288	Disrupted in schizophrenia 1-like. (648 aa)
	I79_002357	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1295 aa)
	I79_002793	Traf2 and NCK-interacting protein kinase. (160 aa)
	I79_002794	Misshapen-like kinase 1. (851 aa)
	Map1a	Microtubule-associated protein 1A. (2585 aa)
	Tyro3	Tyrosine-protein kinase receptor TYRO3. (816 aa)
	Chrna1	Acetylcholine receptor subunit alpha. (442 aa)
	I79_004283	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (906 aa)
	I79_004432	Potassium voltage-gated channel subfamily H member 1. (500 aa)
	Kcnh1	Potassium voltage-gated channel subfamily H member 1. (525 aa)
	Clcn3	Chloride channel protein. (866 aa)
	Adora1	Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (326 aa)
	Ca7	Carbonic anhydrase 7; Belongs to the alpha-carbonic anhydrase family. (208 aa)
	I79_006307	Voltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2208 aa)
	Calb2	Calretinin. (271 aa)
	P2rx2	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (504 aa)
	I79_008358	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (1774 aa)
	I79_008360	Voltage-dependent P/Q-type calcium channel subunit alpha-1A. (79 aa)
	I79_008722	Secretagogin. (240 aa)
	Prkaa1	Non-specific serine/threonine protein kinase. (477 aa)
	Cx3cl1	Fractalkine. (335 aa)
	I79_010710	Peripheral-type benzodiazepine receptor-associated protein 1. (2587 aa)
	I79_010854	MICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (716 aa)
	Atp2b1	Plasma membrane calcium-transporting ATPase 1; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (384 aa)
	I79_011367	Plasma membrane calcium-transporting ATPase 1. (327 aa)
	P2ry1	p2Y purinoceptor 1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
	App	Amyloid beta A4 protein. (433 aa)
	Psen1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
	H671_2g6716	Calbindin-like protein. (211 aa)
	Fggy	FGGY carbohydrate kinase domain-containing protein. (561 aa)
	Taok1	Serine/threonine-protein kinase TAO1. (723 aa)
	I79_013721	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (360 aa)
	I79_013976	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1183 aa)
	Psen2	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (448 aa)
	Htr1b	5-hydroxytryptamine receptor 1B. (386 aa)
	I79_015798	Beta-hexosaminidase subunit beta. (96 aa)
	I79_015800	Beta-hexosaminidase. (527 aa)
	I79_016663	Vesicular glutamate transporter 1. (468 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
App	I79_002288	G3HMG4	G3GX01	Amyloid beta A4 protein.	Disrupted in schizophrenia 1-like.	0.484
App	Psen1	G3HMG4	G3HNF2	Amyloid beta A4 protein.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.971
App	Psen2	G3HMG4	G3HV76	Amyloid beta A4 protein.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.906
Atp2b1	I79_004283	G3HKY3	G3H239	Plasma membrane calcium-transporting ATPase 1; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	0.745
Atp2b1	I79_011367	G3HKY3	G3HKY4	Plasma membrane calcium-transporting ATPase 1; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	Plasma membrane calcium-transporting ATPase 1.	0.557
Ca7	P2ry1	G3H655	G3HL95	Carbonic anhydrase 7; Belongs to the alpha-carbonic anhydrase family.	p2Y purinoceptor 1; Belongs to the G-protein coupled receptor 1 family.	0.435
Dctn1	I79_019613	G3I7W3	G3I7W4	Dynactin subunit 1.	Dynactin subunit 1.	0.900
H671_2g6716	I79_016663	G3HPA1	G3HZZ8	Calbindin-like protein.	Vesicular glutamate transporter 1.	0.423
I79_002288	App	G3GX01	G3HMG4	Disrupted in schizophrenia 1-like.	Amyloid beta A4 protein.	0.484
I79_002357	I79_004283	G3GX45	G3H239	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	0.608
I79_002793	I79_002794	G3GYB8	G3GYB9	Traf2 and NCK-interacting protein kinase.	Misshapen-like kinase 1.	0.879
I79_002794	I79_002793	G3GYB9	G3GYB8	Misshapen-like kinase 1.	Traf2 and NCK-interacting protein kinase.	0.879
I79_004283	Atp2b1	G3H239	G3HKY3	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	Plasma membrane calcium-transporting ATPase 1; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	0.745
I79_004283	I79_002357	G3H239	G3GX45	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.608
I79_004283	I79_011367	G3H239	G3HKY4	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	Plasma membrane calcium-transporting ATPase 1.	0.507
I79_004283	I79_013976	G3H239	G3HSX7	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.585
I79_004432	Kcnh1	G3H2L7	G3H2L9	Potassium voltage-gated channel subfamily H member 1.	Potassium voltage-gated channel subfamily H member 1.	0.907
I79_006307	I79_008358	G3H7H6	G3HCZ0	Voltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents.	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.	0.540
I79_008358	I79_006307	G3HCZ0	G3H7H6	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.	Voltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents.	0.540
I79_011367	Atp2b1	G3HKY4	G3HKY3	Plasma membrane calcium-transporting ATPase 1.	Plasma membrane calcium-transporting ATPase 1; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	0.557