STRINGSTRING
I79_002020 I79_002020 Lpl Lpl Sirt1 Sirt1 Pla2g12b Pla2g12b I79_010883 I79_010883 C1qtnf3 C1qtnf3 Abcg8 Abcg8 Lipc Lipc I79_011250 I79_011250 Xbp1 Xbp1 Apoe Apoe I79_012640 I79_012640 Apoc2 Apoc2 Dgat2 Dgat2 Fundc2 Fundc2 Scarb1 Scarb1 I79_016797 I79_016797 I79_025765 I79_025765 Map2k1 Map2k1 Rora Rora Apoa5 Apoa5 CgPICR_005982 CgPICR_005982 Apoc3 Apoc3 Apoa1 Apoa1 I79_019534 I79_019534 I79_019530 I79_019530 I79_019144 I79_019144 Angptl4 Angptl4 I79_018733 I79_018733 Fitm2 Fitm2 Hnf4a Hnf4a Sesn2 Sesn2 Il18 Il18 Adora1 Adora1 Pnpla8 Pnpla8 Nr1h3 Nr1h3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_002020Glucokinase regulatory protein. (583 aa)
LplLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (450 aa)
Sirt1NAD-dependent deacetylase sirtuin-1. (554 aa)
Pla2g12bGroup XIIB secretory phospholipase A2-like protein. (195 aa)
I79_010883Gastric inhibitory polypeptide. (205 aa)
C1qtnf3Complement C1q tumor necrosis factor-related protein 3. (319 aa)
Abcg8ATP-binding cassette sub-family G member 8. (951 aa)
LipcHepatic triacylglycerol lipase. (470 aa)
I79_011250Protein cTAGE-6. (240 aa)
Xbp1X-box binding protein 1 isoform 1. (330 aa)
ApoeApolipoprotein E. (313 aa)
I79_012640Apolipoprotein C-IV. (158 aa)
Apoc2Apolipoprotein C-II. (100 aa)
Dgat2Diacylglycerol O-acyltransferase 2. (388 aa)
Fundc2FUN14 domain-containing protein 2. (151 aa)
Scarb1Scavenger receptor class B member 1; Belongs to the CD36 family. (509 aa)
I79_016797Dual specificity mitogen-activated protein kinase kinase 1. (129 aa)
I79_025765ATP-binding cassette sub-family G member 8. (192 aa)
Map2k1Dual specificity mitogen-activated protein kinase kinase 1. (101 aa)
RoraNuclear receptor ROR-alpha. (959 aa)
Apoa5Apolipoprotein A-V. (363 aa)
CgPICR_005982Apolipoprotein A-IV. (230 aa)
Apoc3Apolipoprotein C-III. (76 aa)
Apoa1Apolipoprotein A-I. (264 aa)
I79_019534Cutaneous T-cell lymphoma-associated antigen 5-like. (475 aa)
I79_019530Cutaneous T-cell lymphoma-associated antigen 5. (158 aa)
I79_019144Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1336 aa)
Angptl4Angiopoietin-related protein 4. (411 aa)
I79_018733Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1. (247 aa)
Fitm2Fat storage-inducing transmembrane protein 2. (262 aa)
Hnf4aHepatocyte nuclear factor 4-alpha. (464 aa)
Sesn2Sestrin-2. (480 aa)
Il18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (196 aa)
Adora1Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (326 aa)
Pnpla8Calcium-independent phospholipase A2-gamma. (777 aa)
Nr1h3Oxysterols receptor LXR-alpha. (402 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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