STRINGSTRING
I79_017136 I79_017136 I79_016908 I79_016908 PPARG PPARG Slc9a1 Slc9a1 Abraxas2 Abraxas2 I79_010839 I79_010839 Dnajc3 Dnajc3 Rnf34 Rnf34 Nfe2l1 Nfe2l1 Prkaca Prkaca Cirbp Cirbp I79_010207 I79_010207 I79_023284 I79_023284 Saxo2 Saxo2 I79_021176 I79_021176 I79_020576 I79_020576 I79_017638 I79_017638 I79_017637 I79_017637
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_017136Protein FAM154A. (475 aa)
I79_016908Hormone-sensitive lipase. (326 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa)
Slc9a1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (821 aa)
Abraxas2BRISC complex subunit Abro1. (415 aa)
I79_010839Eukaryotic translation initiation factor 2-alpha kinase 3. (783 aa)
Dnajc3DnaJ-like subfamily C member 3. (502 aa)
Rnf34E3 ubiquitin-protein ligase RNF34. (378 aa)
Nfe2l1Nuclear factor erythroid 2-related factor 1. (740 aa)
PrkacacAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
CirbpCold-inducible RNA-binding protein. (184 aa)
I79_010207Eukaryotic translation initiation factor 2-alpha kinase 4. (1513 aa)
I79_023284Protein FAM154A. (409 aa)
Saxo2Protein FAM154B. (244 aa)
I79_021176Perilipin; Belongs to the perilipin family. (518 aa)
I79_020576Mitochondrial brown fat uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (267 aa)
I79_017638Transient receptor potential cation channel subfamily A member 1. (312 aa)
I79_017637Transient receptor potential cation channel subfamily A member 1. (291 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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