STRINGSTRING
Uimc1 Uimc1 I79_025821 I79_025821 Wdr81 Wdr81 I79_024092 I79_024092 Prpf8 Prpf8 H671_3g8906 H671_3g8906 Rnf169 Rnf169 Faap20 Faap20 Tnip2 Tnip2 Tab3 Tab3 Parp10 Parp10 Zranb1 Zranb1 Otud7a Otud7a Sqstm1 Sqstm1 Atrip Atrip Rnf31 Rnf31 Zbtb1 Zbtb1 Tab2 Tab2 Otud7b Otud7b Zranb3 Zranb3 Sprtn Sprtn Tnfaip3 Tnfaip3 Optn Optn RNF168 RNF168 I79_026056 I79_026056 I79_025983 I79_025983 I79_025881 I79_025881
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Uimc1BRCA1-A complex subunit RAP80. (722 aa)
I79_025821Pre-mRNA-processing-splicing factor 8. (264 aa)
Wdr81WD repeat-containing protein 81. (1934 aa)
I79_024092Pre-mRNA-processing-splicing factor 8. (189 aa)
Prpf8Pre-mRNA-processing-splicing factor 8. (365 aa)
H671_3g8906OTU domain-containing protein 7B-like protein. (175 aa)
Rnf169RING finger protein 169. (537 aa)
Faap20Uncharacterized protein C1orf86-like. (266 aa)
Tnip2TNFAIP3-interacting protein 2. (431 aa)
Tab3Mitogen-activated protein kinase kinase kinase 7-interacting protein 3. (715 aa)
Parp10Poly [ADP-ribose] polymerase. (986 aa)
Zranb1Ubiquitin thioesterase Zranb1. (602 aa)
Otud7aOTU domain-containing protein 7A. (715 aa)
Sqstm1Sequestosome-1. (358 aa)
AtripATR-interacting protein. (690 aa)
Rnf31RING finger protein 31. (1065 aa)
Zbtb1Zinc finger and BTB domain-containing protein 1. (713 aa)
Tab2Mitogen-activated protein kinase kinase kinase 7-interacting protein 2. (693 aa)
Otud7bOTU domain-containing protein 7B. (841 aa)
Zranb3Zinc finger Ran-binding domain-containing protein 3. (723 aa)
SprtnZinc finger RAD18 domain-containing protein C1orf124-like. (502 aa)
Tnfaip3Tumor necrosis factor, alpha-induced protein 3. (776 aa)
OptnOptineurin. (623 aa)
RNF168E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (564 aa)
I79_026056Pre-mRNA-processing-splicing factor 8. (184 aa)
I79_025983Pre-mRNA-processing-splicing factor 8. (197 aa)
I79_025881Pre-mRNA-processing-splicing factor 8. (318 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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