STRINGSTRING
Znf683 Znf683 Pik3ca Pik3ca CgPICR_003438 CgPICR_003438 I79_000973 I79_000973 Cldn1 Cldn1 I79_000439 I79_000439 I79_015503 I79_015503 Smarcd1 Smarcd1 Adipoq Adipoq I79_016391 I79_016391 Tlr4 Tlr4 I79_016392 I79_016392 I79_016393 I79_016393 I79_016394 I79_016394 I79_016395 I79_016395 Alad Alad I79_011940 I79_011940 Id3 Id3 Hmgcs2 Hmgcs2 CgPICR_018825 CgPICR_018825 Pdk3 Pdk3 Pon1 Pon1 I79_014111 I79_014111 Pdk4 Pdk4 Foxo1 Foxo1 I79_017077 I79_017077 Dgat2 Dgat2 I79_015046 I79_015046 I79_015205 I79_015205 Edn1 Edn1 Cat Cat Src Src Foxo3 Foxo3 Gnpat Gnpat Ptgs2 Ptgs2 Insig2 Insig2 I79_005332 I79_005332 Xrcc5 Xrcc5 Ptafr Ptafr I79_006180 I79_006180 Adipor2 Adipor2 E2f1 E2f1 Zc3h12a Zc3h12a Ranbp1 Ranbp1 I79_009728 I79_009728 Dkk4 Dkk4 I79_010155 I79_010155 Lpl Lpl LDLR LDLR Cpt1a Cpt1a Pid1 Pid1 Ass1 Ass1 H671_3g10186 H671_3g10186 I79_022371 I79_022371 I79_022055 I79_022055 Irs1 Irs1 I79_020576 I79_020576 Ucp3 Ucp3 Slc2a2 Slc2a2 Acsl1 Acsl1 Hif3a Hif3a I79_018654 I79_018654
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Znf683Zinc finger protein 683. (424 aa)
Pik3caPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (86 aa)
CgPICR_003438C-C motif chemokine. (143 aa)
I79_000973Transcription factor SOX-10. (360 aa)
Cldn1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
I79_000439Phosphoinositide phospholipase C. (949 aa)
I79_015503Transcription factor HES-1. (92 aa)
Smarcd1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1. (453 aa)
AdipoqAdiponectin. (248 aa)
I79_016391Acyl-CoA desaturase 1; Belongs to the fatty acid desaturase type 1 family. (254 aa)
Tlr4Toll-like receptor 4; Belongs to the Toll-like receptor family. (838 aa)
I79_016392Acyl-CoA desaturase 1; Belongs to the fatty acid desaturase type 1 family. (338 aa)
I79_016393Acyl-CoA desaturase 2; Belongs to the fatty acid desaturase type 1 family. (358 aa)
I79_016394Acyl-CoA desaturase 1. (67 aa)
I79_016395Acyl-CoA desaturase 2; Belongs to the fatty acid desaturase type 1 family. (310 aa)
AladDelta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (330 aa)
I79_011940Platelet glycoprotein 4; Belongs to the CD36 family. (348 aa)
Id3DNA-binding protein inhibitor ID-3. (119 aa)
Hmgcs23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
CgPICR_018825Cell division protein kinase 4. (121 aa)
Pdk3Protein-serine/threonine kinase. (415 aa)
Pon1Serum paraoxonase/arylesterase 1. (355 aa)
I79_014111Protein-serine/threonine kinase. (60 aa)
Pdk4Protein-serine/threonine kinase. (178 aa)
Foxo1Forkhead box protein O1. (469 aa)
I79_017077Acetoacetyl-CoA synthetase. (634 aa)
Dgat2Diacylglycerol O-acyltransferase 2. (388 aa)
I79_015046Low-density lipoprotein receptor. (160 aa)
I79_015205Cell division protein kinase 4; Belongs to the protein kinase superfamily. (367 aa)
Edn1Endothelin-1. (202 aa)
CatCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (555 aa)
SrcTyrosine-protein kinase. (536 aa)
Foxo3Forkhead box protein O3. (672 aa)
GnpatDihydroxyacetone phosphate acyltransferase. (669 aa)
Ptgs2Prostaglandin G/H synthase 2. (604 aa)
Insig2Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa)
I79_005332Carbamoyl-phosphate synthase [ammonia], mitochondrial. (1309 aa)
Xrcc5X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (732 aa)
PtafrPlatelet-activating factor receptor; Belongs to the G-protein coupled receptor 1 family. (341 aa)
I79_006180Neuroendocrine convertase 1; Belongs to the peptidase S8 family. (627 aa)
Adipor2Adiponectin receptor protein 2. (386 aa)
E2f1Transcription factor E2F1. (367 aa)
Zc3h12aRibonuclease ZC3H12A. (577 aa)
Ranbp1Ran-specific GTPase-activating protein. (220 aa)
I79_009728Thromboxane-A synthase; Belongs to the cytochrome P450 family. (453 aa)
Dkk4Salivary plasminogen activator alpha 2. (675 aa)
I79_010155Sterol regulatory element-binding protein 1. (1050 aa)
LplLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (450 aa)
LDLRLow-density lipoprotein receptor; Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits; Belongs to the LDLR family. (862 aa)
Cpt1aCarnitine O-palmitoyltransferase 1, liver isoform. (127 aa)
Pid1PTB-containing, cubilin and LRP1-interacting protein. (159 aa)
Ass1Argininosuccinate synthase. (242 aa)
H671_3g10186Olfactory receptor. (320 aa)
I79_022371Cell division protein kinase 4. (143 aa)
I79_022055Argininosuccinate synthase. (97 aa)
Irs1Insulin receptor substrate 1. (1233 aa)
I79_020576Mitochondrial brown fat uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (267 aa)
Ucp3Mitochondrial uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (650 aa)
Slc2a2Solute carrier family 2, facilitated glucose transporter member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (351 aa)
Acsl1Long-chain-fatty-acid--CoA ligase 1. (724 aa)
Hif3aSerine/threonine-protein phosphatase 5. (607 aa)
I79_018654Carnitine O-palmitoyltransferase 1, liver isoform. (467 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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