(26 nodes) Dynein complex binding network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

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co-expression

protein homology

Your Input:
	I79_000275	Dynein assembly factor 1, axonemal. (437 aa)
	I79_000307	Coiled-coil domain-containing protein 37. (582 aa)
	Tpr	Nucleoprotein TPR. (2122 aa)
	I79_002698	Coiled-coil domain-containing protein 42A. (282 aa)
	KATNA1-2	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal p [...] (491 aa)
	CUNH16orf71	Uncharacterized protein C16orf71-like. (502 aa)
	PAFAH1B1	Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
	I79_016662	Coiled-coil domain-containing protein 155. (629 aa)
	I79_000037	F-box/WD repeat-containing protein 11. (481 aa)
	Atmin	ATM interactor. (664 aa)
	I79_017912	Nuclear mitotic apparatus protein 1; Belongs to the transient receptor (TC 1.A.4) family. (3026 aa)
	Katnb1	Katanin p80 WD40-containing subunit B1. (320 aa)
	I79_019222	Coiled-coil domain-containing protein 42B. (274 aa)
	Gpsm2	G-protein-signaling modulator 2. (659 aa)
	Bicd1	Protein bicaudal D-like 1. (288 aa)
	Gsk3b	Glycogen synthase kinase-3 beta. (328 aa)
	Apc	Adenomatous polyposis coli protein. (2488 aa)
	I79_010620	Alpha-synuclein; Belongs to the synuclein family. (166 aa)
	H671_3g8974	F-box/WD repeat-containing protein 11. (122 aa)
	I79_012168	Fragile X mental retardation 1 protein. (560 aa)
	I79_023253	ATM interactor. (56 aa)
	I79_023826	Structural maintenance of chromosomes protein 3. (923 aa)
	Cenpf	Centromere protein F. (2981 aa)
	Hdac6	Histone deacetylase 6. (666 aa)
	I79_012537	Protein bicaudal D-like 2. (783 aa)
	Dctn6	Dynactin subunit 6. (190 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Apc	Gsk3b	G3HF07	G3HAI0	Adenomatous polyposis coli protein.	Glycogen synthase kinase-3 beta.	0.995
Apc	H671_3g8974	G3HF07	G3HJ61	Adenomatous polyposis coli protein.	F-box/WD repeat-containing protein 11.	0.554
Apc	I79_000037	G3HF07	G3GR94	Adenomatous polyposis coli protein.	F-box/WD repeat-containing protein 11.	0.554
Bicd1	Dctn6	G3IDF7	G3H615	Protein bicaudal D-like 1.	Dynactin subunit 6.	0.545
Bicd1	I79_012537	G3IDF7	G3HP33	Protein bicaudal D-like 1.	Protein bicaudal D-like 2.	0.692
Bicd1	PAFAH1B1	G3IDF7	G3HVB8	Protein bicaudal D-like 1.	Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...]	0.679
Dctn6	Bicd1	G3H615	G3IDF7	Dynactin subunit 6.	Protein bicaudal D-like 1.	0.545
Dctn6	I79_012537	G3H615	G3HP33	Dynactin subunit 6.	Protein bicaudal D-like 2.	0.552
Dctn6	PAFAH1B1	G3H615	G3HVB8	Dynactin subunit 6.	Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...]	0.685
Gpsm2	I79_017912	G3IC72	G3I3A8	G-protein-signaling modulator 2.	Nuclear mitotic apparatus protein 1; Belongs to the transient receptor (TC 1.A.4) family.	0.936
Gsk3b	Apc	G3HAI0	G3HF07	Glycogen synthase kinase-3 beta.	Adenomatous polyposis coli protein.	0.995
Gsk3b	H671_3g8974	G3HAI0	G3HJ61	Glycogen synthase kinase-3 beta.	F-box/WD repeat-containing protein 11.	0.664
Gsk3b	I79_000037	G3HAI0	G3GR94	Glycogen synthase kinase-3 beta.	F-box/WD repeat-containing protein 11.	0.664
H671_3g8974	Apc	G3HJ61	G3HF07	F-box/WD repeat-containing protein 11.	Adenomatous polyposis coli protein.	0.554
H671_3g8974	Gsk3b	G3HJ61	G3HAI0	F-box/WD repeat-containing protein 11.	Glycogen synthase kinase-3 beta.	0.664
I79_000037	Apc	G3GR94	G3HF07	F-box/WD repeat-containing protein 11.	Adenomatous polyposis coli protein.	0.554
I79_000037	Gsk3b	G3GR94	G3HAI0	F-box/WD repeat-containing protein 11.	Glycogen synthase kinase-3 beta.	0.664
I79_000307	I79_002698	G3GS00	G3GY43	Coiled-coil domain-containing protein 37.	Coiled-coil domain-containing protein 42A.	0.412
I79_000307	I79_019222	G3GS00	G3I6U4	Coiled-coil domain-containing protein 37.	Coiled-coil domain-containing protein 42B.	0.412
I79_002698	I79_000307	G3GY43	G3GS00	Coiled-coil domain-containing protein 42A.	Coiled-coil domain-containing protein 37.	0.412