(11 nodes) snRNP binding network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	I79_024174	U1 small nuclear ribonucleoprotein A. (104 aa)
	Strap	Serine-threonine kinase receptor-associated protein. (309 aa)
	SNRPD1	Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (119 aa)
	I79_012406	U1 small nuclear ribonucleoprotein A. (291 aa)
	SNRPD2	Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (108 aa)
	Snrpd3	Small nuclear ribonucleoprotein Sm D3. (84 aa)
	Snrpb2	U2 small nuclear ribonucleoprotein B. (180 aa)
	Snrnp70	U1 small nuclear ribonucleoprotein 70 kDa. (445 aa)
	Snrpb	Small nuclear ribonucleoprotein-associated protein. (223 aa)
	Prpf31	U4/U6 small nuclear ribonucleoprotein Prp31. (441 aa)
	I79_022290	U2 small nuclear ribonucleoprotein B. (113 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
I79_012406	I79_022290	G3HNR3	G3IEY4	U1 small nuclear ribonucleoprotein A.	U2 small nuclear ribonucleoprotein B.	0.449
I79_012406	Prpf31	G3HNR3	G3I346	U1 small nuclear ribonucleoprotein A.	U4/U6 small nuclear ribonucleoprotein Prp31.	0.727
I79_012406	SNRPD1	G3HNR3	G3HGH4	U1 small nuclear ribonucleoprotein A.	Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA.	0.919
I79_012406	SNRPD2	G3HNR3	G3HPF1	U1 small nuclear ribonucleoprotein A.	Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome.	0.913
I79_012406	Snrnp70	G3HNR3	G3HZY5	U1 small nuclear ribonucleoprotein A.	U1 small nuclear ribonucleoprotein 70 kDa.	0.943
I79_012406	Snrpb	G3HNR3	G3H453	U1 small nuclear ribonucleoprotein A.	Small nuclear ribonucleoprotein-associated protein.	0.666
I79_012406	Snrpb2	G3HNR3	G3HY27	U1 small nuclear ribonucleoprotein A.	U2 small nuclear ribonucleoprotein B.	0.450
I79_012406	Snrpd3	G3HNR3	G3HY23	U1 small nuclear ribonucleoprotein A.	Small nuclear ribonucleoprotein Sm D3.	0.908
I79_022290	I79_012406	G3IEY4	G3HNR3	U2 small nuclear ribonucleoprotein B.	U1 small nuclear ribonucleoprotein A.	0.449
I79_022290	I79_024174	G3IEY4	G3IJY3	U2 small nuclear ribonucleoprotein B.	U1 small nuclear ribonucleoprotein A.	0.455
I79_022290	Prpf31	G3IEY4	G3I346	U2 small nuclear ribonucleoprotein B.	U4/U6 small nuclear ribonucleoprotein Prp31.	0.729
I79_022290	SNRPD1	G3IEY4	G3HGH4	U2 small nuclear ribonucleoprotein B.	Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA.	0.930
I79_022290	SNRPD2	G3IEY4	G3HPF1	U2 small nuclear ribonucleoprotein B.	Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome.	0.895
I79_022290	Snrnp70	G3IEY4	G3HZY5	U2 small nuclear ribonucleoprotein B.	U1 small nuclear ribonucleoprotein 70 kDa.	0.874
I79_022290	Snrpb	G3IEY4	G3H453	U2 small nuclear ribonucleoprotein B.	Small nuclear ribonucleoprotein-associated protein.	0.590
I79_022290	Snrpd3	G3IEY4	G3HY23	U2 small nuclear ribonucleoprotein B.	Small nuclear ribonucleoprotein Sm D3.	0.899
I79_024174	I79_022290	G3IJY3	G3IEY4	U1 small nuclear ribonucleoprotein A.	U2 small nuclear ribonucleoprotein B.	0.455
I79_024174	Prpf31	G3IJY3	G3I346	U1 small nuclear ribonucleoprotein A.	U4/U6 small nuclear ribonucleoprotein Prp31.	0.727
I79_024174	SNRPD1	G3IJY3	G3HGH4	U1 small nuclear ribonucleoprotein A.	Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA.	0.919
I79_024174	SNRPD2	G3IJY3	G3HPF1	U1 small nuclear ribonucleoprotein A.	Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome.	0.913