(19 nodes) U2-type catalytic step 1 spliceosome network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CgPICR_014750	Eukaryotic initiation factor 4A-III. (115 aa)
	Casc3	Protein CASC3. (620 aa)
	I79_021945	Pre-mRNA-processing factor 19. (487 aa)
	Prpf8	Pre-mRNA-processing-splicing factor 8. (365 aa)
	I79_024092	Pre-mRNA-processing-splicing factor 8. (189 aa)
	I79_025821	Pre-mRNA-processing-splicing factor 8. (264 aa)
	I79_025881	Pre-mRNA-processing-splicing factor 8. (318 aa)
	I79_025983	Pre-mRNA-processing-splicing factor 8. (197 aa)
	I79_026056	Pre-mRNA-processing-splicing factor 8. (184 aa)
	Yju2	Coiled-coil domain-containing protein 94-like isoform 2. (313 aa)
	Snrnp200	U5 small nuclear ribonucleoprotein 200 kDa helicase. (1377 aa)
	Rbm8a	RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (171 aa)
	Cwc25	Coiled-coil domain-containing protein 49. (419 aa)
	I79_009487	Coiled-coil domain-containing protein 94. (229 aa)
	Isy1	Pre-mRNA-splicing factor ISY1-like. (285 aa)
	I79_013671	Pre-mRNA-splicing factor RBM22. (241 aa)
	Eif4a3	Eukaryotic initiation factor 4A-III. (279 aa)
	I79_014275	RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (179 aa)
	CgPICR_014751	Eukaryotic initiation factor 4A-III. (250 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Casc3	CgPICR_014750	G3I5M8	G3I1W5	Protein CASC3.	Eukaryotic initiation factor 4A-III.	0.937
Casc3	CgPICR_014751	G3I5M8	G3I1W4	Protein CASC3.	Eukaryotic initiation factor 4A-III.	0.937
Casc3	Cwc25	G3I5M8	G3H5W3	Protein CASC3.	Coiled-coil domain-containing protein 49.	0.525
Casc3	Eif4a3	G3I5M8	G3HTE6	Protein CASC3.	Eukaryotic initiation factor 4A-III.	0.937
Casc3	I79_009487	G3I5M8	G3HFX0	Protein CASC3.	Coiled-coil domain-containing protein 94.	0.448
Casc3	I79_013671	G3I5M8	G3HS45	Protein CASC3.	Pre-mRNA-splicing factor RBM22.	0.525
Casc3	I79_014275	G3I5M8	G3HTP7	Protein CASC3.	RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.	0.996
Casc3	I79_021945	G3I5M8	G3IE04	Protein CASC3.	Pre-mRNA-processing factor 19.	0.525
Casc3	Isy1	G3I5M8	G3HID7	Protein CASC3.	Pre-mRNA-splicing factor ISY1-like.	0.448
Casc3	Rbm8a	G3I5M8	G3H2S5	Protein CASC3.	RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.	0.996
Casc3	Snrnp200	G3I5M8	G3H037	Protein CASC3.	U5 small nuclear ribonucleoprotein 200 kDa helicase.	0.594
Casc3	Yju2	G3I5M8	G3HCF1	Protein CASC3.	Coiled-coil domain-containing protein 94-like isoform 2.	0.448
CgPICR_014750	Casc3	G3I1W5	G3I5M8	Eukaryotic initiation factor 4A-III.	Protein CASC3.	0.937
CgPICR_014750	CgPICR_014751	G3I1W5	G3I1W4	Eukaryotic initiation factor 4A-III.	Eukaryotic initiation factor 4A-III.	0.951
CgPICR_014750	Cwc25	G3I1W5	G3H5W3	Eukaryotic initiation factor 4A-III.	Coiled-coil domain-containing protein 49.	0.554
CgPICR_014750	I79_009487	G3I1W5	G3HFX0	Eukaryotic initiation factor 4A-III.	Coiled-coil domain-containing protein 94.	0.476
CgPICR_014750	I79_013671	G3I1W5	G3HS45	Eukaryotic initiation factor 4A-III.	Pre-mRNA-splicing factor RBM22.	0.680
CgPICR_014750	I79_014275	G3I1W5	G3HTP7	Eukaryotic initiation factor 4A-III.	RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.	0.847
CgPICR_014750	I79_021945	G3I1W5	G3IE04	Eukaryotic initiation factor 4A-III.	Pre-mRNA-processing factor 19.	0.710
CgPICR_014750	I79_024092	G3I1W5	G3IJQ6	Eukaryotic initiation factor 4A-III.	Pre-mRNA-processing-splicing factor 8.	0.581