STRINGSTRING
I79_019135 I79_019135 Pdcd4 Pdcd4 I79_019425 I79_019425 Ccdc142 Ccdc142 Ccl5 Ccl5 Stat1 Stat1 I79_020321 I79_020321 Hnrnpul1 Hnrnpul1 Tgfb1 Tgfb1 Chmp5 Chmp5 I79_021151 I79_021151 Rela Rela I79_021950 I79_021950 I79_022023 I79_022023 I79_022055 I79_022055 I79_022126 I79_022126 Jak2 Jak2 I79_022343 I79_022343 I79_022400 I79_022400 I79_022945 I79_022945 I79_023218 I79_023218 Il1f10 Il1f10 Il36rn Il36rn Prpf8 Prpf8 I79_024092 I79_024092 Il36g Il36g I79_024535 I79_024535 Tnfrsf1b Tnfrsf1b I79_024961 I79_024961 I79_024962 I79_024962 I79_024975 I79_024975 I79_022371 I79_022371 Bcl10 Bcl10 Ass1 Ass1 Il36b Il36b I79_025433 I79_025433 I79_025482 I79_025482 I79_025496 I79_025496 I79_025497 I79_025497 I79_025518 I79_025518 Nfkb1 Nfkb1 I79_025535 I79_025535 Csf3 Csf3 I79_025726 I79_025726 I79_025745 I79_025745 I79_025821 I79_025821 I79_025881 I79_025881 Cxcl3 Cxcl3 I79_000054 I79_000054 Tlr5 Tlr5 Plcg2 Plcg2 Slc7a5 Slc7a5 Irf8 Irf8 Nr2c2 Nr2c2 I79_001024 I79_001024 Lyrm9 Lyrm9 CgPICR_003438 CgPICR_003438 Abca1 Abca1 Wnt5a Wnt5a Pde4d Pde4d I79_001592 I79_001592 Prkce Prkce Map2k3 Map2k3 Tnfaip3 Tnfaip3 Litaf Litaf Irak2 Irak2 CgPICR_012593 CgPICR_012593 Cdk19 Cdk19 Hadhb Hadhb Src Src Lbp Lbp Cd68 Cd68 Plscr3 Plscr3 Nr1h3 Nr1h3 Traf6 Traf6 Tlr9 Tlr9 Tnfsf4 Tnfsf4 H671_5g13848 H671_5g13848 I79_004035 I79_004035 Arid5a Arid5a Ptafr Ptafr Il18 Il18 Akt1 Akt1 Ankrd1 Ankrd1 Upf1 Upf1 Cd180 Cd180 I79_005449 I79_005449 Nod2 Nod2 Ghsr Ghsr Cd40 Cd40 Serpine1 Serpine1 I79_007297 I79_007297 Cd86 Cd86 Mef2c Mef2c Il10 Il10 I79_007693 I79_007693 Cmpk2 Cmpk2 I79_007733 I79_007733 Ticam1 Ticam1 I79_008639 I79_008639 I79_008640 I79_008640 IL12B IL12B Zc3h12a Zc3h12a I79_008906 I79_008906 Sbno2 Sbno2 I79_009217 I79_009217 I79_009500 I79_009500 Plaa Plaa I79_010164 I79_010164 I79_010165 I79_010165 Vim Vim I79_010290 I79_010290 Acod1 Acod1 Ephb2 Ephb2 I79_010760 I79_010760 Paf1 Paf1 Zfp36 Zfp36 I79_011011 I79_011011 I79_011017 I79_011017 Mtdh Mtdh Spon2 Spon2 Camp Camp I79_025983 I79_025983 I79_026056 I79_026056 I79_026231 I79_026231 Pde4b Pde4b Akap8 Akap8 I79_011940 I79_011940 Bcr Bcr Gata1 Gata1 Xbp1 Xbp1 Hmgcs2 Hmgcs2 Ripk2 Ripk2 CgPICR_018825 CgPICR_018825 Myd88 Myd88 Cx3cr1 Cx3cr1 Git1 Git1 Cebpe Cebpe I79_013417 I79_013417 Map2k7 Map2k7 Ppard Ppard Tbxa2r Tbxa2r Cactin Cactin I79_013907 I79_013907 Irak1 Irak1 I79_014088 I79_014088 Ticam2 Ticam2 I79_014650 I79_014650 Cdc73 Cdc73 I79_015059 I79_015059 I79_015061 I79_015061 I79_015062 I79_015062 I79_015109 I79_015109 I79_015205 I79_015205 Sgms1 Sgms1 I79_015356 I79_015356 Scarb1 Scarb1 Dab2ip Dab2ip Tspo Tspo I79_015960 I79_015960 Ctr9 Ctr9 Tnf Tnf I79_016473 I79_016473 Pde2a Pde2a Mapk14 Mapk14 Tnip2 Tnip2 Tlr4 Tlr4 Sirpa Sirpa IL1B IL1B Cd80 Cd80 Shpk Shpk I79_017345 I79_017345 Fn1 Fn1 Lyn Lyn I79_017561 I79_017561 I79_017861 I79_017861 Nfkbia Nfkbia I79_018245 I79_018245 I79_018247 I79_018247 Cxcl1 Cxcl1 Mapk3 Mapk3 Cd14 Cd14 Nr1d1 Nr1d1 I79_018785 I79_018785 CgPICR_003405 CgPICR_003405
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_019135GTPase SLIP-GC. (778 aa)
Pdcd4Programmed cell death protein 4. (469 aa)
I79_019425Apoptosis-associated speck-like protein containing a CARD. (192 aa)
Ccdc142Coiled-coil domain-containing protein 142. (723 aa)
Ccl5C-C motif chemokine. (91 aa)
Stat1Signal transducer and activator of transcription. (749 aa)
I79_020321A disintegrin and metalloproteinase with thrombospondin motifs 13. (1304 aa)
Hnrnpul1Heterogeneous nuclear ribonucleoprotein U-like protein 1. (1566 aa)
Tgfb1Transforming growth factor beta-1. (237 aa)
Chmp5Charged multivesicular body protein 5. (160 aa)
I79_021151Ephrin-B2. (178 aa)
RelaTranscription factor p65. (546 aa)
I79_021950T-cell differentiation antigen CD6. (536 aa)
I79_022023Arginase-1; Belongs to the arginase family. (281 aa)
I79_022055Argininosuccinate synthase. (97 aa)
I79_022126Zinc finger protein 709. (421 aa)
Jak2Tyrosine-protein kinase. (1122 aa)
I79_022343UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit. (1444 aa)
I79_022400Nucleolin. (479 aa)
I79_022945Immunity-related GTPase family M protein. (285 aa)
I79_023218Interferon regulatory factor 3. (377 aa)
Il1f10Interleukin-1. (152 aa)
Il36rnInterleukin-1. (145 aa)
Prpf8Pre-mRNA-processing-splicing factor 8. (365 aa)
I79_024092Pre-mRNA-processing-splicing factor 8. (189 aa)
Il36gInterleukin-1. (143 aa)
I79_024535Protein FAM127C. (132 aa)
Tnfrsf1bTumor necrosis factor receptor superfamily member 1B. (477 aa)
I79_024961Uncharacterized protein C19orf29-like. (328 aa)
I79_024962Uncharacterized protein C19orf29-like. (171 aa)
I79_024975Ephrin-B2. (148 aa)
I79_022371Cell division protein kinase 4. (143 aa)
Bcl10B-cell lymphoma/leukemia 10. (232 aa)
Ass1Argininosuccinate synthase. (242 aa)
Il36bInterleukin-1. (138 aa)
I79_025433Ephrin-B2; Belongs to the ephrin family. (70 aa)
I79_025482Nuclear factor NF-kappa-B p105 subunit. (144 aa)
I79_025496Ephrin-B2. (147 aa)
I79_025497Ephrin-B2; Belongs to the ephrin family. (69 aa)
I79_025518Ephrin-B2. (123 aa)
Nfkb1Nuclear factor NF-kappa-B p105 subunit. (509 aa)
I79_025535Ephrin-B2. (125 aa)
Csf3Granulocyte colony-stimulating factor. (208 aa)
I79_025726Ephrin-B2. (121 aa)
I79_025745Nuclear receptor subfamily 1 group D member 1. (226 aa)
I79_025821Pre-mRNA-processing-splicing factor 8. (264 aa)
I79_025881Pre-mRNA-processing-splicing factor 8. (318 aa)
Cxcl3C-X-C motif chemokine. (101 aa)
I79_000054Calpain-2 catalytic subunit; Belongs to the peptidase C2 family. (668 aa)
Tlr5Toll-like receptor 5; Belongs to the Toll-like receptor family. (858 aa)
Plcg21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1199 aa)
Slc7a5Large neutral amino acids transporter small subunit 1. (506 aa)
Irf8Interferon regulatory factor 8. (424 aa)
Nr2c2Nuclear receptor subfamily 2 group C member 2. (596 aa)
I79_001024Ephrin-B2; Belongs to the ephrin family. (373 aa)
Lyrm9Nitric oxide synthase; Produces nitric oxide (NO); Belongs to the complex I LYR family. (1115 aa)
CgPICR_003438C-C motif chemokine. (143 aa)
Abca1ATP-binding cassette sub-family A member 1. (2261 aa)
Wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
Pde4dPhosphodiesterase. (507 aa)
I79_001592Protein kinase C epsilon type. (163 aa)
PrkceProtein kinase C epsilon type. (137 aa)
Map2k3Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (340 aa)
Tnfaip3Tumor necrosis factor, alpha-induced protein 3. (776 aa)
LitafLipopolysaccharide-induced tumor necrosis factor-alpha factor-like. (161 aa)
Irak2Interleukin-1 receptor-associated kinase-like 2. (626 aa)
CgPICR_012593Charged multivesicular body protein 5. (131 aa)
Cdk19Cell division cycle 2-like protein kinase 6. (404 aa)
HadhbTrifunctional enzyme subunit beta, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family. (367 aa)
SrcTyrosine-protein kinase. (536 aa)
LbpLipopolysaccharide-binding protein. (916 aa)
Cd68Macrosialin. (294 aa)
Plscr3Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (295 aa)
Nr1h3Oxysterols receptor LXR-alpha. (402 aa)
Traf6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (508 aa)
Tlr9Toll-like receptor 9. (1239 aa)
Tnfsf4Tumor necrosis factor ligand superfamily member 4; Belongs to the tumor necrosis factor family. (185 aa)
H671_5g13848Interleukin-24-like protein. (160 aa)
I79_004035Disintegrin and metalloproteinase domain-containing protein 9. (1196 aa)
Arid5aAT-rich interactive domain-containing protein 5A. (588 aa)
PtafrPlatelet-activating factor receptor; Belongs to the G-protein coupled receptor 1 family. (341 aa)
Il18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (196 aa)
Akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
Ankrd1Ankyrin repeat domain-containing protein 1. (319 aa)
Upf1Regulator of nonsense transcripts 1. (771 aa)
Cd180CD180 antigen. (525 aa)
I79_005449TNFAIP3-interacting protein 1. (623 aa)
Nod2Nucleotide-binding oligomerization domain-containing protein 2. (989 aa)
GhsrGrowth hormone secretagogue receptor type 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
Cd40Tumor necrosis factor receptor superfamily member 5. (118 aa)
Serpine1Plasminogen activator inhibitor 1; Belongs to the serpin family. (270 aa)
I79_007297Plasminogen activator inhibitor 1; Belongs to the serpin family. (108 aa)
Cd86T-lymphocyte activation antigen CD86. (269 aa)
Mef2cMyocyte-specific enhancer factor 2C. (465 aa)
Il10Interleukin-10. (178 aa)
I79_007693Nitric oxide synthase; Produces nitric oxide (NO). (1129 aa)
Cmpk2UMP-CMP kinase 2, mitochondrial. (223 aa)
I79_007733Defensin-related cryptdin-related sequence 10; Belongs to the alpha-defensin family. (60 aa)
Ticam1TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (699 aa)
I79_008639NF-kappa-B inhibitor alpha. (52 aa)
I79_008640NF-kappa-B inhibitor alpha. (90 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (327 aa)
Zc3h12aRibonuclease ZC3H12A. (577 aa)
I79_008906Zinc finger protein Gfi-1. (333 aa)
Sbno2Protein strawberry notch-like 2. (669 aa)
I79_009217Protein strawberry notch-like 2. (527 aa)
I79_009500Mitogen-activated protein kinase 1. (68 aa)
PlaaPhospholipase A-2-activating protein. (795 aa)
I79_010164Macrophage mannose receptor 1. (112 aa)
I79_010165Macrophage mannose receptor 1. (598 aa)
VimVimentin; Belongs to the intermediate filament family. (466 aa)
I79_010290Endothelin B receptor; Belongs to the G-protein coupled receptor 1 family. (361 aa)
Acod1Immune-responsive gene 1 protein. (290 aa)
Ephb2Ephrin type-B receptor 2. (1018 aa)
I79_010760NF-kappa-B inhibitor beta. (138 aa)
Paf1RNA polymerase II-associated factor 1-like. (537 aa)
Zfp36Tristetraproline. (315 aa)
I79_011011E3 ubiquitin-protein ligase TRIM 41. (258 aa)
I79_011017Immunity-related GTPase family M protein. (341 aa)
MtdhProtein LYRIC. (247 aa)
Spon2Spondin-2. (312 aa)
CampCathelin-related antimicrobial peptide. (108 aa)
I79_025983Pre-mRNA-processing-splicing factor 8. (197 aa)
I79_026056Pre-mRNA-processing-splicing factor 8. (184 aa)
I79_026231Ephrin-B2; Belongs to the ephrin family. (68 aa)
Pde4bPhosphodiesterase. (517 aa)
Akap8A-kinase anchor protein 8; Belongs to the AKAP95 family. (690 aa)
I79_011940Platelet glycoprotein 4; Belongs to the CD36 family. (348 aa)
BcrBreakpoint cluster region protein. (1193 aa)
Gata1Erythroid transcription factor-like protein. (330 aa)
Xbp1X-box binding protein 1 isoform 1. (330 aa)
Hmgcs23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
Ripk2Receptor-interacting serine/threonine-protein kinase 2. (402 aa)
CgPICR_018825Cell division protein kinase 4. (121 aa)
Myd88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
Cx3cr1CX3C chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa)
Git1ARF GTPase-activating protein GIT1. (809 aa)
CebpeCCAAT/enhancer-binding protein. (281 aa)
I79_013417Polyadenylate-binding protein 2. (244 aa)
Map2k7Dual specificity mitogen-activated protein kinase kinase 7. (391 aa)
PpardPeroxisome proliferator-activated receptor delta. (440 aa)
Tbxa2rThromboxane A2 receptor-like protein; Belongs to the G-protein coupled receptor 1 family. (339 aa)
CactinUncharacterized protein C19orf29-like. (425 aa)
I79_013907Ephrin-B2. (148 aa)
Irak1Interleukin-1 receptor-associated kinase 1. (494 aa)
I79_014088TNFAIP3-interacting protein 3. (113 aa)
Ticam2TIR domain-containing adapter molecule 2. (233 aa)
I79_014650Parafibromin. (260 aa)
Cdc73Parafibromin. (164 aa)
I79_015059Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (163 aa)
I79_015061Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (146 aa)
I79_015062Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (390 aa)
I79_015109Interleukin-6. (174 aa)
I79_015205Cell division protein kinase 4; Belongs to the protein kinase superfamily. (367 aa)
Sgms1Phosphatidylcholine:ceramide cholinephosphotransferase 1. (414 aa)
I79_015356Heat shock factor protein 1. (524 aa)
Scarb1Scavenger receptor class B member 1; Belongs to the CD36 family. (509 aa)
Dab2ipDisabled-like 2-interacting protein. (1065 aa)
TspoTranslocator protein. (169 aa)
I79_015960Nucleolin. (108 aa)
Ctr9RNA polymerase-associated protein CTR9-like. (1171 aa)
TnfTumor necrosis factor; Belongs to the tumor necrosis factor family. (234 aa)
I79_016473NF-kappa-B inhibitor-like protein 1. (292 aa)
Pde2acGMP-dependent 3',5'-cyclic phosphodiesterase; Belongs to the cyclic nucleotide phosphodiesterase family. (216 aa)
Mapk14Mitogen-activated protein kinase. (349 aa)
Tnip2TNFAIP3-interacting protein 2. (431 aa)
Tlr4Toll-like receptor 4; Belongs to the Toll-like receptor family. (838 aa)
SirpaTyrosine-protein phosphatase non-receptor type substrate 1. (522 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa)
Cd80T-lymphocyte activation antigen CD80. (177 aa)
ShpkSedoheptulokinase. (125 aa)
I79_017345Activation-induced cytidine deaminase. (261 aa)
Fn1Fibronectin. (2486 aa)
LynTyrosine-protein kinase. (289 aa)
I79_017561Tyrosine-protein kinase Lyn. (101 aa)
I79_017861Solute carrier family 12 member 2. (706 aa)
NfkbiaNF-kappa-B inhibitor alpha. (224 aa)
I79_018245C-X-C motif chemokine. (322 aa)
I79_018247C-X-C motif chemokine 15. (63 aa)
Cxcl1C-X-C motif chemokine. (101 aa)
Mapk3Mitogen-activated protein kinase. (408 aa)
Cd14Monocyte differentiation antigen CD14. (309 aa)
Nr1d1Nuclear receptor subfamily 1 group D member 1. (508 aa)
I79_018785Retinoic acid receptor alpha. (484 aa)
CgPICR_003405C-C motif chemokine. (98 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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