STRINGSTRING
Bak1 Bak1 Piezo1 Piezo1 I79_000233 I79_000233 I79_000973 I79_000973 Kcnj2 Kcnj2 Nos1 Nos1 Tnfrsf1a Tnfrsf1a Ltbr Ltbr Rac1 Rac1 Ptgs2 Ptgs2 Agt Agt Arhgdia Arhgdia Map2k4 Map2k4 Got1 Got1 I79_004244 I79_004244 Akt1 Akt1 Mkx Mkx Ankrd1 Ankrd1 I79_005551 I79_005551 Atp1a2 Atp1a2 Dag1 Dag1 Cd40 Cd40 Atp1a1 Atp1a1 Ctnnb1 Ctnnb1 Ednra Ednra Cav1 Cav1 Gsk3b Gsk3b I79_007693 I79_007693 Tnfsf14 Tnfsf14 Bmp6 Bmp6 H671_3g11194 H671_3g11194 I79_008941 I79_008941 Cnn2 Cnn2 Slc2a1 Slc2a1 Itgb3 Itgb3 I79_010073 I79_010073 Map3k1 Map3k1 Gclc Gclc Aqp1 Aqp1 Col1a1 Col1a1 Igf1r Igf1r Casp2 Casp2 Map3k14 Map3k14 I79_012903 I79_012903 Fadd Fadd Myd88 Myd88 Cradd Cradd I79_013709 I79_013709 Wnt11 Wnt11 I79_015358 I79_015358 I79_015916 I79_015916 Hdac4 Hdac4 Pde2a Pde2a Tlr4 Tlr4 IL1B IL1B Mapk3 Mapk3 Il33 Il33 Slc38a2 Slc38a2 CgPICR_018361 CgPICR_018361 Chek1 Chek1 Tlr8 Tlr8 Tlr7 Tlr7 Tgfb1 Tgfb1 I79_020948 I79_020948 I79_020958 I79_020958 Habp4 Habp4 I79_021155 I79_021155 Bag3 Bag3 I79_021331 I79_021331 I79_022271 I79_022271 Bnip3 Bnip3 Tlr3 Tlr3 Bcl10 Bcl10 I79_025482 I79_025482 Nfkb1 Nfkb1 Gja1 Gja1 Casp8 Casp8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Bak1Bcl-2-likeous antagonist/killer. (209 aa)
Piezo1Protein FAM38A. (1724 aa)
I79_000233Cytochrome b-245 light chain. (206 aa)
I79_000973Transcription factor SOX-10. (360 aa)
Kcnj2Inward rectifier potassium channel 2. (427 aa)
Nos1Nitric oxide synthase; Produces nitric oxide (NO). (1413 aa)
Tnfrsf1aTumor necrosis factor receptor superfamily member 1A. (355 aa)
LtbrTumor necrosis factor receptor superfamily member 3. (412 aa)
Rac1Ras-related C3 botulinum toxin substrate 1. (148 aa)
Ptgs2Prostaglandin G/H synthase 2. (604 aa)
AgtAngiotensinogen; Belongs to the serpin family. (477 aa)
ArhgdiaRho GDP-dissociation inhibitor 1-like protein. (204 aa)
Map2k4Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (342 aa)
Got1Aspartate aminotransferase. (413 aa)
I79_004244Tyrosine-protein phosphatase non-receptor type 11. (583 aa)
Akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
MkxHomeobox protein Mohawk. (352 aa)
Ankrd1Ankyrin repeat domain-containing protein 1. (319 aa)
I79_005551Piezo-type mechanosensitive ion channel component. (2258 aa)
Atp1a2Sodium/potassium-transporting ATPase subunit alpha-2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1194 aa)
Dag1Dystroglycan. (893 aa)
Cd40Tumor necrosis factor receptor superfamily member 5. (118 aa)
Atp1a1Sodium/potassium-transporting ATPase subunit alpha. (773 aa)
Ctnnb1Catenin beta-1. (781 aa)
EdnraEndothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (412 aa)
Cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
Gsk3bGlycogen synthase kinase-3 beta. (328 aa)
I79_007693Nitric oxide synthase; Produces nitric oxide (NO). (1129 aa)
Tnfsf14Tumor necrosis factor ligand superfamily member 14. (238 aa)
Bmp6Bone morphogenetic protein 6. (296 aa)
H671_3g11194Protein FAM65B-like protein. (890 aa)
I79_008941Receptor protein-tyrosine kinase. (962 aa)
Cnn2Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (299 aa)
Slc2a1Solute carrier family 2, facilitated glucose transporter member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (486 aa)
Itgb3Integrin beta; Belongs to the integrin beta chain family. (975 aa)
I79_010073Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (511 aa)
Map3k1Mitogen-activated protein kinase kinase kinase 1. (1340 aa)
GclcGlutamate--cysteine ligase catalytic subunit. (584 aa)
Aqp1Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa)
Col1a1Collagen alpha-1(I) chain. (355 aa)
Igf1rInsulin-like growth factor 1 receptor. (191 aa)
Casp2Caspase-2; Belongs to the peptidase C14A family. (421 aa)
Map3k14Mitogen-activated protein kinase kinase kinase 14. (564 aa)
I79_012903Pulmonary surfactant-associated protein A. (238 aa)
FaddFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
Myd88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
CraddDeath domain-containing protein CRADD. (117 aa)
I79_013709Death domain-containing protein CRADD. (120 aa)
Wnt11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
I79_015358Basic helix-loop-helix transcription factor scleraxis. (191 aa)
I79_015916Insulin-like growth factor II. (155 aa)
Hdac4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (966 aa)
Pde2acGMP-dependent 3',5'-cyclic phosphodiesterase; Belongs to the cyclic nucleotide phosphodiesterase family. (216 aa)
Tlr4Toll-like receptor 4; Belongs to the Toll-like receptor family. (838 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa)
Mapk3Mitogen-activated protein kinase. (408 aa)
Il33Interleukin-33. (217 aa)
Slc38a2Sodium-coupled neutral amino acid transporter 2. (504 aa)
CgPICR_018361Transmembrane protein 150B. (249 aa)
Chek1Serine/threonine-protein kinase Chk1; Belongs to the protein kinase superfamily. (476 aa)
Tlr8Toll-like receptor 8; Belongs to the Toll-like receptor family. (1027 aa)
Tlr7Toll-like receptor 7; Belongs to the Toll-like receptor family. (1033 aa)
Tgfb1Transforming growth factor beta-1. (237 aa)
I79_020948Interferon regulatory factor 1. (369 aa)
I79_020958Intracellular hyaluronan-binding protein 4. (123 aa)
Habp4Intracellular hyaluronan-binding protein 4. (216 aa)
I79_021155Paired box protein Pax-2. (503 aa)
Bag3BAG family molecular chaperone regulator 3. (571 aa)
I79_021331Mitogen-activated protein kinase kinase kinase 14. (446 aa)
I79_022271Ras-related C3 botulinum toxin substrate 2. (178 aa)
Bnip3BCL2/adenovirus E1B 19 kDa protein-interacting protein 3. (151 aa)
Tlr3Toll-like receptor 3. (164 aa)
Bcl10B-cell lymphoma/leukemia 10. (232 aa)
I79_025482Nuclear factor NF-kappa-B p105 subunit. (144 aa)
Nfkb1Nuclear factor NF-kappa-B p105 subunit. (509 aa)
Gja1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa)
Casp8Caspase-8; Belongs to the peptidase C14A family. (481 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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