(25 nodes) Cellular response to cadmium ion network (Cricetulus griseus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Fos	Proto-oncogene protein c-fos. (381 aa)
	I79_021045	Heme oxygenase 1. (81 aa)
	Hmox1	Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (290 aa)
	Daxx	Death domain-associated protein 6. (708 aa)
	CgPICR_012539	Small ubiquitin-related modifier. (112 aa)
	Mapk3	Mitogen-activated protein kinase. (408 aa)
	Chuk	Inhibitor of nuclear factor kappa-B kinase subunit alpha. (647 aa)
	I79_016007	Cytochrome b-245 heavy chain. (396 aa)
	Foxa2	Hepatocyte nuclear factor 3-beta. (430 aa)
	Gsn	Gelsolin. (658 aa)
	I79_015356	Heat shock factor protein 1. (524 aa)
	Abcb6	ATP-binding cassette sub-family B member 6, mitochondrial. (228 aa)
	I79_012926	Death domain-associated protein 6. (393 aa)
	Mapk9	Mitogen-activated protein kinase 9. (303 aa)
	Atp7a	Copper-transporting ATPase 1. (1457 aa)
	Ncf1	Neutrophil cytosol factor 1. (303 aa)
	Sox2	Transcription factor SOX-2. (273 aa)
	I79_010470	Metallothionein-3; Belongs to the metallothionein superfamily. Type 1 family. (108 aa)
	I79_009953	Transcription factor AP-1. (72 aa)
	I79_009500	Mitogen-activated protein kinase 1. (68 aa)
	I79_008941	Receptor protein-tyrosine kinase. (962 aa)
	Cer1	Cerberus. (272 aa)
	Mmp9	Matrix metalloproteinase-9. (710 aa)
	Akt1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	Ogg1	N-glycosylase/DNA lyase. (335 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Akt1	Chuk	G3H397	G3HZA3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Inhibitor of nuclear factor kappa-B kinase subunit alpha.	0.988
Akt1	Fos	G3H397	G3HFR4	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Proto-oncogene protein c-fos.	0.417
Akt1	I79_008941	G3H397	G3HEF7	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Receptor protein-tyrosine kinase.	0.409
Akt1	I79_009500	G3H397	G3HFY3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase 1.	0.546
Akt1	I79_009953	G3H397	G3HH56	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Transcription factor AP-1.	0.958
Akt1	I79_016007	G3H397	G3HY84	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Cytochrome b-245 heavy chain.	0.687
Akt1	Mapk3	G3H397	G3I4H1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.947
Akt1	Mmp9	G3H397	G3H8V1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Matrix metalloproteinase-9.	0.550
Akt1	Ncf1	G3H397	G3HLN8	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Neutrophil cytosol factor 1.	0.722
Akt1	Sox2	G3H397	G3HJZ4	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Transcription factor SOX-2.	0.404
CgPICR_012539	Daxx	G3I572	G3I6W2	Small ubiquitin-related modifier.	Death domain-associated protein 6.	0.677
CgPICR_012539	I79_012926	G3I572	G3HQ34	Small ubiquitin-related modifier.	Death domain-associated protein 6.	0.525
Chuk	Akt1	G3HZA3	G3H397	Inhibitor of nuclear factor kappa-B kinase subunit alpha.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.988
Daxx	CgPICR_012539	G3I6W2	G3I572	Death domain-associated protein 6.	Small ubiquitin-related modifier.	0.677
Daxx	Mapk9	G3I6W2	G3HP57	Death domain-associated protein 6.	Mitogen-activated protein kinase 9.	0.910
Fos	Akt1	G3HFR4	G3H397	Proto-oncogene protein c-fos.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.417
Fos	Foxa2	G3HFR4	G3HXU7	Proto-oncogene protein c-fos.	Hepatocyte nuclear factor 3-beta.	0.457
Fos	I79_008941	G3HFR4	G3HEF7	Proto-oncogene protein c-fos.	Receptor protein-tyrosine kinase.	0.558
Fos	I79_009500	G3HFR4	G3HFY3	Proto-oncogene protein c-fos.	Mitogen-activated protein kinase 1.	0.722
Fos	I79_009953	G3HFR4	G3HH56	Proto-oncogene protein c-fos.	Transcription factor AP-1.	0.999