(37 nodes) Cellular response to fatty acid network (Cricetulus griseus)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	I79_000439	Phosphoinositide phospholipase C. (949 aa)
	Cldn1	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
	CgPICR_003438	C-C motif chemokine. (143 aa)
	Src	Tyrosine-protein kinase. (536 aa)
	Edn1	Endothelin-1. (202 aa)
	Ptafr	Platelet-activating factor receptor; Belongs to the G-protein coupled receptor 1 family. (341 aa)
	Xrcc5	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (732 aa)
	I79_005332	Carbamoyl-phosphate synthase [ammonia], mitochondrial. (1309 aa)
	Lpl	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (450 aa)
	Adipor2	Adiponectin receptor protein 2. (386 aa)
	E2f1	Transcription factor E2F1. (367 aa)
	Zc3h12a	Ribonuclease ZC3H12A. (577 aa)
	Ranbp1	Ran-specific GTPase-activating protein. (220 aa)
	I79_010155	Sterol regulatory element-binding protein 1. (1050 aa)
	Id3	DNA-binding protein inhibitor ID-3. (119 aa)
	Hmgcs2	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
	CgPICR_018825	Cell division protein kinase 4. (121 aa)
	Pdk3	Protein-serine/threonine kinase. (415 aa)
	I79_014111	Protein-serine/threonine kinase. (60 aa)
	Pdk4	Protein-serine/threonine kinase. (178 aa)
	Dgat2	Diacylglycerol O-acyltransferase 2. (388 aa)
	I79_015046	Low-density lipoprotein receptor. (160 aa)
	I79_015205	Cell division protein kinase 4; Belongs to the protein kinase superfamily. (367 aa)
	I79_015503	Transcription factor HES-1. (92 aa)
	Smarcd1	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1. (453 aa)
	Znf683	Zinc finger protein 683. (424 aa)
	I79_018654	Carnitine O-palmitoyltransferase 1, liver isoform. (467 aa)
	Slc2a2	Solute carrier family 2, facilitated glucose transporter member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (351 aa)
	I79_020576	Mitochondrial brown fat uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (267 aa)
	Irs1	Insulin receptor substrate 1. (1233 aa)
	I79_022055	Argininosuccinate synthase. (97 aa)
	I79_022371	Cell division protein kinase 4. (143 aa)
	H671_3g10186	Olfactory receptor. (320 aa)
	Ass1	Argininosuccinate synthase. (242 aa)
	Pid1	PTB-containing, cubilin and LRP1-interacting protein. (159 aa)
	Cpt1a	Carnitine O-palmitoyltransferase 1, liver isoform. (127 aa)
	LDLR	Low-density lipoprotein receptor; Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits; Belongs to the LDLR family. (862 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Adipor2	I79_010155	G3H867	G3HHP9	Adiponectin receptor protein 2.	Sterol regulatory element-binding protein 1.	0.457
Ass1	I79_005332	G3IMU3	G3H4W9	Argininosuccinate synthase.	Carbamoyl-phosphate synthase [ammonia], mitochondrial.	0.957
Ass1	I79_022055	G3IMU3	G3IEB0	Argininosuccinate synthase.	Argininosuccinate synthase.	0.951
CgPICR_003438	Edn1	G3GTT2	G3H0G9	C-C motif chemokine.	Endothelin-1.	0.446
CgPICR_018825	E2f1	G3HQ42	G3HAM7	Cell division protein kinase 4.	Transcription factor E2F1.	0.778
Cpt1a	I79_018654	G3INS2	G3I5B0	Carnitine O-palmitoyltransferase 1, liver isoform.	Carnitine O-palmitoyltransferase 1, liver isoform.	0.520
Cpt1a	Pdk4	G3INS2	G3HT90	Carnitine O-palmitoyltransferase 1, liver isoform.	Protein-serine/threonine kinase.	0.450
Dgat2	I79_010155	G3HUS2	G3HHP9	Diacylglycerol O-acyltransferase 2.	Sterol regulatory element-binding protein 1.	0.494
Dgat2	Lpl	G3HUS2	G3H6V7	Diacylglycerol O-acyltransferase 2.	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	0.468
E2f1	CgPICR_018825	G3HAM7	G3HQ42	Transcription factor E2F1.	Cell division protein kinase 4.	0.778
E2f1	I79_015205	G3HAM7	G3HW57	Transcription factor E2F1.	Cell division protein kinase 4; Belongs to the protein kinase superfamily.	0.577
E2f1	I79_022371	G3HAM7	G3IF55	Transcription factor E2F1.	Cell division protein kinase 4.	0.577
Edn1	CgPICR_003438	G3H0G9	G3GTT2	Endothelin-1.	C-C motif chemokine.	0.446
Edn1	I79_000439	G3H0G9	G3GSB8	Endothelin-1.	Phosphoinositide phospholipase C.	0.617
Edn1	Src	G3H0G9	G3GXX7	Endothelin-1.	Tyrosine-protein kinase.	0.463
Hmgcs2	I79_010155	G3HP76	G3HHP9	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Sterol regulatory element-binding protein 1.	0.442
I79_000439	Edn1	G3GSB8	G3H0G9	Phosphoinositide phospholipase C.	Endothelin-1.	0.617
I79_000439	Ptafr	G3GSB8	G3H1Z5	Phosphoinositide phospholipase C.	Platelet-activating factor receptor; Belongs to the G-protein coupled receptor 1 family.	0.417
I79_005332	Ass1	G3H4W9	G3IMU3	Carbamoyl-phosphate synthase [ammonia], mitochondrial.	Argininosuccinate synthase.	0.957
I79_005332	I79_022055	G3H4W9	G3IEB0	Carbamoyl-phosphate synthase [ammonia], mitochondrial.	Argininosuccinate synthase.	0.902