STRINGSTRING
Cd81 Cd81 Itgb1 Itgb1 I79_018761 I79_018761 I79_018762 I79_018762 I79_018763 I79_018763 Lpl Lpl I79_019630 I79_019630 Cd9 Cd9 I79_021093 I79_021093 Socs5 Socs5 I79_019629 I79_019629 Cdh13 Cdh13 I79_019626 I79_019626 I79_019625 I79_019625 Syk Syk Itgb2 Itgb2 I79_010458 I79_010458 I79_011940 I79_011940 Hmgcs1 Hmgcs1 I79_014078 I79_014078 PPARG PPARG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Cd81Tetraspanin. (236 aa)
Itgb1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
I79_018761Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (448 aa)
I79_018762Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (370 aa)
I79_018763Liver carboxylesterase 4. (393 aa)
LplLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (450 aa)
I79_019630Liver carboxylesterase 1; Belongs to the type-B carboxylesterase/lipase family. (765 aa)
Cd9Tetraspanin. (159 aa)
I79_021093Sterol regulatory element-binding protein 2. (2034 aa)
Socs5Suppressor of cytokine signaling 5. (530 aa)
I79_019629Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (564 aa)
Cdh13Cadherin-13. (377 aa)
I79_019626Liver carboxylesterase 4. (105 aa)
I79_019625Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (514 aa)
SykTyrosine-protein kinase. (611 aa)
Itgb2Integrin beta. (769 aa)
I79_010458Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (451 aa)
I79_011940Platelet glycoprotein 4; Belongs to the CD36 family. (348 aa)
Hmgcs13-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (520 aa)
I79_014078Niemann-Pick C1 protein. (1137 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.