STRINGSTRING
Igf1r Igf1r Mstn Mstn I79_023721 I79_023721 I79_023010 I79_023010 Yes1 Yes1 I79_022455 I79_022455 I79_022023 I79_022023 I79_021938 I79_021938 Acvrl1 Acvrl1 Ppm1a Ppm1a I79_020548 I79_020548 Tgfb1 Tgfb1 Nox4 Nox4 I79_019934 I79_019934 I79_019499 I79_019499 Ptk2 Ptk2 I79_019127 I79_019127 Fermt2 Fermt2 Glg1 Glg1 I79_017669 I79_017669 Tab1 Tab1 I79_017529 I79_017529 Fn1 Fn1 Col4a2 Col4a2 I79_016923 I79_016923 H671_1g1119 H671_1g1119 Pde2a Pde2a I79_016547 I79_016547 Twsg1 Twsg1 Pdgfd Pdgfd Ppargc1a Ppargc1a I79_015358 I79_015358 Foxh1 Foxh1 I79_015320 I79_015320 Stk16 Stk16 Parp1 Parp1 I79_014818 I79_014818 Amhr2 Amhr2 Cilp Cilp I79_014474 I79_014474 Smad4 Smad4 Crk Crk Bambi Bambi I79_013556 I79_013556 I79_013541 I79_013541 Cx3cr1 Cx3cr1 Chst11 Chst11 Ddr2 Ddr2 Smad7 Smad7 Clec3b Clec3b Runx1 Runx1 Fyn Fyn I79_011919 I79_011919 I79_011918 I79_011918 Stat3 Stat3 Zyx Zyx Col1a1 Col1a1 Mtmr4 Mtmr4 I79_010639 I79_010639 Wwox Wwox Smad5 Smad5 Wnt4 Wnt4 Skil Skil Map3k1 Map3k1 Hdac2 Hdac2 I79_010194 I79_010194 Acvr1 Acvr1 Sfrp1 Sfrp1 I79_010003 I79_010003 I79_009953 I79_009953 I79_009916 I79_009916 I79_009834 I79_009834 Smad9 Smad9 Crkl Crkl Tgfb3 Tgfb3 Fos Fos I79_009362 I79_009362 I79_009361 I79_009361 Cldn5 Cldn5 Nr3c1 Nr3c1 Pml Pml Tgfbr3 Tgfbr3 I79_008828 I79_008828 Fut8 Fut8 I79_007693 I79_007693 Mef2c Mef2c Smad2 Smad2 Sirt1 Sirt1 I79_007297 I79_007297 Serpine1 Serpine1 I79_007088 I79_007088 Wnt2 Wnt2 Cav1 Cav1 Cav2 Cav2 Smad1 Smad1 Smad3 Smad3 Smad6 Smad6 I79_006745 I79_006745 Itgb6 Itgb6 Hyal2 Hyal2 Tgfbr1 Tgfbr1 Nodal Nodal I79_005895 I79_005895 Dnmt1 Dnmt1 Cdh5 Cdh5 I79_005543 I79_005543 Epb41l5 Epb41l5 Ankrd1 Ankrd1 Sox5 Sox5 I79_004750 I79_004750 Zfp36l1 Zfp36l1 I79_004035 I79_004035 Dbn1 Dbn1 Edn1 Edn1 Actr3 Actr3 I79_002785 I79_002785 Src Src Col1a2 Col1a2 Dusp22 Dusp22 Zfyve9 Zfyve9 I79_001871 I79_001871 I79_001733 I79_001733 Tgfbr2 Tgfbr2 Wnt5a Wnt5a Appl1 Appl1 Dlx1 Dlx1 I79_001232 I79_001232 Pxn Pxn CgPICR_003438 CgPICR_003438 Nlk Nlk I79_000973 I79_000973 Cldn1 Cldn1 I79_000697 I79_000697 Itgb5 Itgb5 Nrros Nrros Pak2 Pak2 Usp9x Usp9x Wnt7a Wnt7a I79_000092 I79_000092 I79_000024 I79_000024 FSHB FSHB I79_025783 I79_025783 I79_025513 I79_025513 I79_025459 I79_025459 I79_025316 I79_025316 I79_024959 I79_024959 Col3a1 Col3a1 CgPICR_015515 CgPICR_015515 Fgfr2 Fgfr2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Igf1rInsulin-like growth factor 1 receptor. (191 aa)
MstnGrowth/differentiation factor 8. (295 aa)
I79_023721Leupaxin. (365 aa)
I79_023010Latent-transforming growth factor beta-binding protein 3. (624 aa)
Yes1Tyrosine-protein kinase. (541 aa)
I79_022455Receptor-type tyrosine-protein phosphatase kappa. (375 aa)
I79_022023Arginase-1; Belongs to the arginase family. (281 aa)
I79_021938Mothers against decapentaplegic-like 1. (122 aa)
Acvrl1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (776 aa)
Ppm1aProtein phosphatase 1A. (382 aa)
I79_020548Receptor-type tyrosine-protein phosphatase kappa. (858 aa)
Tgfb1Transforming growth factor beta-1. (237 aa)
Nox4NADPH oxidase 4. (130 aa)
I79_019934Mitogen-activated protein kinase kinase kinase 7-interacting protein 1. (263 aa)
I79_019499Collagen alpha-2(IV) chain. (324 aa)
Ptk2Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1027 aa)
I79_019127Integrin beta; Belongs to the integrin beta chain family. (435 aa)
Fermt2Fermitin family-like 2. (575 aa)
Glg1Golgi apparatus protein 1. (308 aa)
I79_017669Apoptotic protease-activating factor 1. (434 aa)
Tab1Mitogen-activated protein kinase kinase kinase 7-interacting protein 1. (336 aa)
I79_017529Apoptotic protease-activating factor 1. (444 aa)
Fn1Fibronectin. (2486 aa)
Col4a2Collagen alpha-2(IV) chain. (350 aa)
I79_016923Programmed cell death protein 5. (96 aa)
H671_1g111915-hydroxyprostaglandin dehydrogenase [NAD+]-like protein. (208 aa)
Pde2acGMP-dependent 3',5'-cyclic phosphodiesterase; Belongs to the cyclic nucleotide phosphodiesterase family. (216 aa)
I79_016547DCC-interacting protein 13-beta. (634 aa)
Twsg1Twisted gastrulation protein-like 1. (222 aa)
PdgfdPlatelet-derived growth factor D. (253 aa)
Ppargc1aPeroxisome proliferator-activated receptor gamma coactivator 1-alpha. (894 aa)
I79_015358Basic helix-loop-helix transcription factor scleraxis. (191 aa)
Foxh1Forkhead box protein H1. (367 aa)
I79_015320Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (477 aa)
Stk16Serine/threonine-protein kinase 16. (213 aa)
Parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (971 aa)
I79_014818Anti-Muellerian hormone type-2 receptor. (73 aa)
Amhr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (57 aa)
CilpCartilage intermediate layer protein 1. (1160 aa)
I79_014474Cyclic AMP-responsive element-binding protein 1. (325 aa)
Smad4Mothers against decapentaplegic-like 4. (259 aa)
CrkProto-oncogene C-crk. (327 aa)
BambiBMP and activin membrane-bound inhibitor-like. (218 aa)
I79_013556Fibrillin-1. (2698 aa)
I79_013541Uncharacterized protein. (83 aa)
Cx3cr1CX3C chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa)
Chst11Carbohydrate sulfotransferase. (352 aa)
Ddr2Discoidin domain-containing receptor 2. (854 aa)
Smad7Mothers against decapentaplegic-like 7. (256 aa)
Clec3bTetranectin-like protein. (202 aa)
Runx1Runt-related transcription factor 1. (462 aa)
FynProto-oncogene tyrosine-protein kinase Fyn. (232 aa)
I79_011919Transcription factor SOX-6. (237 aa)
I79_011918Transcription factor Sox-6. (395 aa)
Stat3Signal transducer and activator of transcription. (770 aa)
ZyxZyxin. (480 aa)
Col1a1Collagen alpha-1(I) chain. (355 aa)
Mtmr4Myotubularin-related protein 4. (1200 aa)
I79_010639WW domain-containing oxidoreductase. (138 aa)
WwoxWW domain-containing oxidoreductase. (193 aa)
Smad5Mothers against decapentaplegic homolog. (462 aa)
Wnt4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (288 aa)
SkilSki-like protein. (677 aa)
Map3k1Mitogen-activated protein kinase kinase kinase 1. (1340 aa)
Hdac2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (458 aa)
I79_010194Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (387 aa)
Acvr1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
Sfrp1Secreted frizzled-related protein 1. (104 aa)
I79_010003Zinc finger MIZ domain-containing protein 1. (960 aa)
I79_009953Transcription factor AP-1. (72 aa)
I79_009916Phosphodiesterase. (693 aa)
I79_009834Disabled-like 2. (705 aa)
Smad9Mothers against decapentaplegic homolog. (465 aa)
CrklCrk-like protein. (303 aa)
Tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
FosProto-oncogene protein c-fos. (381 aa)
I79_009362N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase. (228 aa)
I79_009361N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase. (344 aa)
Cldn5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (238 aa)
Nr3c1Glucocorticoid receptor. (748 aa)
PmlPutative transcription factor PML. (540 aa)
Tgfbr3TGF-beta receptor type III. (849 aa)
I79_008828Lymphotactin. (114 aa)
Fut8Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Belongs to the glycosyltransferase 23 family. (575 aa)
I79_007693Nitric oxide synthase; Produces nitric oxide (NO). (1129 aa)
Mef2cMyocyte-specific enhancer factor 2C. (465 aa)
Smad2Mothers against decapentaplegic homolog. (467 aa)
Sirt1NAD-dependent deacetylase sirtuin-1. (554 aa)
I79_007297Plasminogen activator inhibitor 1; Belongs to the serpin family. (108 aa)
Serpine1Plasminogen activator inhibitor 1; Belongs to the serpin family. (270 aa)
I79_007088Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (870 aa)
Wnt2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (321 aa)
Cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
Cav2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
Smad1Mothers against decapentaplegic-like 1. (232 aa)
Smad3Mothers against decapentaplegic homolog. (363 aa)
Smad6Mothers against decapentaplegic-like 6. (174 aa)
I79_006745Mothers against decapentaplegic-like 6. (71 aa)
Itgb6Integrin beta; Belongs to the integrin beta chain family. (792 aa)
Hyal2Hyaluronidase. (359 aa)
Tgfbr1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (401 aa)
NodalNodal. (309 aa)
I79_005895DNA (Cytosine-5)-methyltransferase 1. (85 aa)
Dnmt1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1494 aa)
Cdh5Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins. (763 aa)
I79_005543One cut domain family member 2. (50 aa)
Epb41l5Band 4.1-like protein 5. (717 aa)
Ankrd1Ankyrin repeat domain-containing protein 1. (319 aa)
Sox5Transcription factor SOX-5. (347 aa)
I79_004750Transcription factor SOX-5. (211 aa)
Zfp36l1Butyrate response factor 1. (338 aa)
I79_004035Disintegrin and metalloproteinase domain-containing protein 9. (1196 aa)
Dbn1Drebrin. (597 aa)
Edn1Endothelin-1. (202 aa)
Actr3Actin-related protein 3; Belongs to the actin family. (418 aa)
I79_002785Beta-arrestin-2. (65 aa)
SrcTyrosine-protein kinase. (536 aa)
Col1a2Collagen alpha-2(I) chain. (621 aa)
Dusp22Dual specificity protein phosphatase 22. (197 aa)
Zfyve9Zinc finger FYVE domain-containing protein. (1413 aa)
I79_001871Transcription factor Ovo-like 2. (213 aa)
I79_001733Mitogen-activated protein kinase. (1186 aa)
Tgfbr2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
Wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
Appl1DCC-interacting protein 13-alpha. (664 aa)
Dlx1Homeobox protein DLX-1. (255 aa)
I79_001232Paxillin; Belongs to the phospholipase A2 family. (642 aa)
PxnPaxillin. (388 aa)
CgPICR_003438C-C motif chemokine. (143 aa)
NlkSerine/threonine protein kinase NLK. (410 aa)
I79_000973Transcription factor SOX-10. (360 aa)
Cldn1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
I79_000697Mitogen-activated protein kinase kinase kinase 7. (287 aa)
Itgb5Integrin beta; Belongs to the integrin beta chain family. (771 aa)
NrrosLeucine-rich repeat-containing protein 33. (692 aa)
Pak2Non-specific serine/threonine protein kinase. (524 aa)
Usp9xPutative ubiquitin carboxyl-terminal hydrolase FAF-X; Belongs to the peptidase C19 family. (2558 aa)
Wnt7aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (282 aa)
I79_000092Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
I79_000024Aldo-keto reductase family 1 member C18. (219 aa)
FSHBFollicle stimulating hormone beta-subunit protein. (129 aa)
I79_025783Mothers against decapentaplegic-like 1. (97 aa)
I79_025513Mothers against decapentaplegic-like 1. (151 aa)
I79_025459Mothers against decapentaplegic-like 1. (117 aa)
I79_025316Mothers against decapentaplegic-like 1. (104 aa)
I79_024959Mothers against decapentaplegic-like 1. (161 aa)
Col3a1Collagen alpha-1(III) chain. (1051 aa)
CgPICR_015515N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase. (311 aa)
Fgfr2Fibroblast growth factor receptor 2. (659 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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