(15 nodes) Cellular response to epinephrine stimulus network (Cricetulus griseus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	I79_024406	A-kinase anchor protein 6. (211 aa)
	Nos1	Nitric oxide synthase; Produces nitric oxide (NO). (1413 aa)
	Pde4d	Phosphodiesterase. (507 aa)
	Pklr	Pyruvate kinase; Belongs to the pyruvate kinase family. (543 aa)
	Srd5a1	3-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)). (255 aa)
	Sirt2	NAD-dependent deacetylase sirtuin-2. (83 aa)
	Pde4b	Phosphodiesterase. (517 aa)
	I79_012424	Ryanodine receptor 2. (2535 aa)
	I79_012425	Ryanodine receptor 2. (2233 aa)
	Atp2b4	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1189 aa)
	I79_015904	Potassium voltage-gated channel subfamily KQT member 1. (216 aa)
	Kcnq1	Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. (308 aa)
	Adipoq	Adiponectin. (248 aa)
	Slc9a1	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (821 aa)
	Akap6	A-kinase anchor protein 6. (1368 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Akap6	I79_012424	G3IAI2	G3HNS9	A-kinase anchor protein 6.	Ryanodine receptor 2.	0.488
Akap6	I79_012425	G3IAI2	G3HNT1	A-kinase anchor protein 6.	Ryanodine receptor 2.	0.488
Akap6	I79_024406	G3IAI2	G3IKK3	A-kinase anchor protein 6.	A-kinase anchor protein 6.	0.921
Akap6	Pde4d	G3IAI2	G3GV13	A-kinase anchor protein 6.	Phosphodiesterase.	0.489
Atp2b4	Nos1	G3HQC3	G3GU55	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Nitric oxide synthase; Produces nitric oxide (NO).	0.798
I79_012424	Akap6	G3HNS9	G3IAI2	Ryanodine receptor 2.	A-kinase anchor protein 6.	0.488
I79_012424	I79_012425	G3HNS9	G3HNT1	Ryanodine receptor 2.	Ryanodine receptor 2.	0.943
I79_012424	I79_024406	G3HNS9	G3IKK3	Ryanodine receptor 2.	A-kinase anchor protein 6.	0.488
I79_012425	Akap6	G3HNT1	G3IAI2	Ryanodine receptor 2.	A-kinase anchor protein 6.	0.488
I79_012425	I79_012424	G3HNT1	G3HNS9	Ryanodine receptor 2.	Ryanodine receptor 2.	0.943
I79_012425	I79_024406	G3HNT1	G3IKK3	Ryanodine receptor 2.	A-kinase anchor protein 6.	0.488
I79_015904	Kcnq1	G3HXY8	G3HXZ0	Potassium voltage-gated channel subfamily KQT member 1.	Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family.	0.898
I79_024406	Akap6	G3IKK3	G3IAI2	A-kinase anchor protein 6.	A-kinase anchor protein 6.	0.921
I79_024406	I79_012424	G3IKK3	G3HNS9	A-kinase anchor protein 6.	Ryanodine receptor 2.	0.488
I79_024406	I79_012425	G3IKK3	G3HNT1	A-kinase anchor protein 6.	Ryanodine receptor 2.	0.488
I79_024406	Pde4d	G3IKK3	G3GV13	A-kinase anchor protein 6.	Phosphodiesterase.	0.489
Kcnq1	I79_015904	G3HXZ0	G3HXY8	Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family.	Potassium voltage-gated channel subfamily KQT member 1.	0.898
Nos1	Atp2b4	G3GU55	G3HQC3	Nitric oxide synthase; Produces nitric oxide (NO).	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.798
Pde4b	Pde4d	G3HLA4	G3GV13	Phosphodiesterase.	Phosphodiesterase.	0.912
Pde4d	Akap6	G3GV13	G3IAI2	Phosphodiesterase.	A-kinase anchor protein 6.	0.489