STRINGSTRING
I79_024203 I79_024203 Ctnnbip1 Ctnnbip1 Pdgfra Pdgfra I79_024483 I79_024483 Umod Umod Mtss1 Mtss1 I79_025269 I79_025269 Commd5 Commd5 Dspp Dspp I79_025625 I79_025625 Wnt9b Wnt9b Myc Myc I79_025974 I79_025974 I79_002900 I79_002900 Smo Smo I79_003731 I79_003731 Nog Nog I79_005331 I79_005331 Dchs2 Dchs2 Sall1 Sall1 I79_006225 I79_006225 I79_006254 I79_006254 Nphs2 Nphs2 I79_006364 I79_006364 Kif26b Kif26b Vangl2 Vangl2 Sulf2 Sulf2 Ctnnb1 Ctnnb1 Ednra Ednra Plce1 Plce1 Lhx1 Lhx1 ilk ilk Gata3 Gata3 I79_000180 I79_000180 Klf15 Klf15 Jag1 Jag1 I79_000930 I79_000930 I79_000973 I79_000973 Six2 Six2 Ahi1 Ahi1 Agt Agt Nup133 Nup133 I79_007089 I79_007089 I79_007090 I79_007090 I79_007229 I79_007229 Ext1 Ext1 I79_007548 I79_007548 Mef2c Mef2c Greb1 Greb1 I79_007744 I79_007744 Angpt2 Angpt2 Bmp7 Bmp7 Pkd1 Pkd1 Sox8 Sox8 CgPICR_019990 CgPICR_019990 I79_008304 I79_008304 Hoxa11 Hoxa11 Osr1 Osr1 Asxl1 Asxl1 Fgf1 Fgf1 Egr1 Egr1 Kirrel3 Kirrel3 I79_009364 I79_009364 Pgf Pgf I79_009699 I79_009699 I79_009708 I79_009708 Lama5 Lama5 I79_009958 I79_009958 I79_010290 I79_010290 Fmn1 Fmn1 I79_010448 I79_010448 Wnt4 Wnt4 Aqp1 Aqp1 Itga3 Itga3 Gdnf Gdnf Pbx1 Pbx1 Magi2 Magi2 I79_011515 I79_011515 I79_011731 I79_011731 I79_011804 I79_011804 Heyl Heyl Podxl Podxl I79_012418 I79_012418 Dll1 Dll1 Notch2 Notch2 H671_2g6716 H671_2g6716 I79_012727 I79_012727 I79_012794 I79_012794 I79_012894 I79_012894 Acta2 Acta2 Nup107 Nup107 Ctnnd1 Ctnnd1 Timeless Timeless I79_013660 I79_013660 Pdgfrb Pdgfrb Ahr Ahr Smad4 Smad4 Foxj1 Foxj1 Wnt11 Wnt11 Gli3 Gli3 I79_015033 I79_015033 I79_015223 I79_015223 I79_015301 I79_015301 I79_015321 I79_015321 I79_015503 I79_015503 Npm3 Npm3 Wwtr1 Wwtr1 Acat1 Acat1 Pdgfb Pdgfb I79_017780 I79_017780 Fat4 Fat4 Gzf1 Gzf1 I79_018113 I79_018113 Aqp11 Aqp11 Hnf1b Hnf1b Tacstd2 Tacstd2 Lgr4 Lgr4 Wnt1 Wnt1 I79_019149 I79_019149 Ampd2 Ampd2 I79_019507 I79_019507 Irx2 Irx2 Irx1 Irx1 Tcf21 Tcf21 Lamb2 Lamb2 I79_021155 I79_021155 I79_021283 I79_021283 Wnt7b Wnt7b Grem1 Grem1 Cd34 Cd34 Mpv17 Mpv17 I79_021721 I79_021721 Six1 Six1 Pax8 Pax8 I79_022733 I79_022733 Enpep Enpep I79_023900 I79_023900 I79_024070 I79_024070 Ptch1 Ptch1 I79_024202 I79_024202
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_024203Sal-like protein 1. (121 aa)
Ctnnbip1Beta-catenin-interacting protein 1. (81 aa)
PdgfraPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1082 aa)
I79_024483Polycystin-2. (192 aa)
UmodUromodulin. (618 aa)
Mtss1Metastasis suppressor protein 1. (526 aa)
I79_025269Glutamyl aminopeptidase. (84 aa)
Commd5COMM domain-containing protein 5. (224 aa)
DsppDentin sialophosphoprotein. (859 aa)
I79_025625Polycystin-2. (318 aa)
Wnt9bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (331 aa)
MycMyc proto-oncogene protein. (281 aa)
I79_025974Metastasis suppressor protein 1. (73 aa)
I79_002900Nuclear pore complex protein Nup160. (1215 aa)
SmoSmoothened-like; Belongs to the G-protein coupled receptor Fz/Smo family. (984 aa)
I79_003731Iroquois-class homeodomain protein IRX-3. (341 aa)
NogNoggin. (117 aa)
I79_005331Receptor tyrosine-protein kinase erbB-4. (480 aa)
Dchs2Protocadherin-23. (1127 aa)
Sall1Sal-like protein 1. (1294 aa)
I79_006225Sonic hedgehog protein. (226 aa)
I79_006254Bone morphogenetic protein 4. (406 aa)
Nphs2Podocin. (392 aa)
I79_006364Kinesin-like protein KIF26B. (158 aa)
Kif26bKinesin-like protein KIF26B. (189 aa)
Vangl2Vang-like protein. (521 aa)
Sulf2Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (875 aa)
Ctnnb1Catenin beta-1. (781 aa)
EdnraEndothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (412 aa)
Plce1Phosphoinositide phospholipase C. (2223 aa)
Lhx1LIM/homeobox protein Lhx1. (84 aa)
ilkIntegrin-linked protein kinase. (452 aa)
Gata3Trans-acting T-cell-specific transcription factor GATA-3. (443 aa)
I79_000180Myosin-Ie; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1021 aa)
Klf15Krueppel-like factor 15. (414 aa)
Jag1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1186 aa)
I79_000930Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (509 aa)
I79_000973Transcription factor SOX-10. (360 aa)
Six2Homeobox protein SIX2. (299 aa)
Ahi1Jouberin. (988 aa)
AgtAngiotensinogen; Belongs to the serpin family. (477 aa)
Nup133Nuclear pore complex protein Nup133. (632 aa)
I79_007089Receptor tyrosine-protein kinase erbB-4. (225 aa)
I79_007090Receptor tyrosine-protein kinase erbB-4. (182 aa)
I79_007229Receptor-type tyrosine-protein phosphatase O. (1056 aa)
Ext1Exostosin-1. (388 aa)
I79_007548Angiopoietin-1. (112 aa)
Mef2cMyocyte-specific enhancer factor 2C. (465 aa)
Greb1Protein GREB1. (1972 aa)
I79_007744Angiopoietin-2. (188 aa)
Angpt2Angiopoietin-2. (288 aa)
Bmp7Bone morphogenetic protein 7. (430 aa)
Pkd1Polycystin-1. (3717 aa)
Sox8Transcription factor SOX-8. (463 aa)
CgPICR_019990Persephin. (157 aa)
I79_008304Platelet endothelial cell adhesion molecule. (596 aa)
Hoxa11Homeobox protein Hox-A11. (250 aa)
Osr1Protein odd-skipped-related 1. (266 aa)
Asxl1Putative Polycomb group protein ASXL1. (1470 aa)
Fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
Egr1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (421 aa)
Kirrel3Kin of IRRE-like protein 3. (753 aa)
I79_009364Transcription factor AP-2 alpha. (411 aa)
PgfPlacenta growth factor; Belongs to the PDGF/VEGF growth factor family. (154 aa)
I79_009699GREB1-like protein. (1598 aa)
I79_009708Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (332 aa)
Lama5Laminin subunit alpha-5. (3735 aa)
I79_009958Angiopoietin-1 receptor. (793 aa)
I79_010290Endothelin B receptor; Belongs to the G-protein coupled receptor 1 family. (361 aa)
Fmn1Formin-1. (644 aa)
I79_010448Formin-1. (1049 aa)
Wnt4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (288 aa)
Aqp1Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa)
Itga3Integrin alpha-3; Belongs to the integrin alpha chain family. (1051 aa)
GdnfGlial cell line-derived neurotrophic factor. (160 aa)
Pbx1Pre-B-cell leukemia transcription factor 1. (325 aa)
Magi2Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2. (483 aa)
I79_011515Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2. (343 aa)
I79_011731Serine/threonine-protein kinase WNK4. (1139 aa)
I79_011804Neurogenic locus notch-like protein 3. (2181 aa)
HeylHairy/enhancer-of-split related with YRPW motif-like protein. (300 aa)
PodxlPodocalyxin-like protein 1. (387 aa)
I79_012418Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2. (120 aa)
Dll1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (741 aa)
Notch2Neurogenic locus notch-like protein 2. (1521 aa)
H671_2g6716Calbindin-like protein. (211 aa)
I79_012727Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (441 aa)
I79_012794Nephrin. (1049 aa)
I79_012894Transcription factor AP-2 beta. (287 aa)
Acta2Actin, aortic smooth muscle-like isoform 1. (443 aa)
Nup107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (931 aa)
Ctnnd1Catenin delta-1. (932 aa)
TimelessProtein timeless-like. (1200 aa)
I79_013660Beta-type platelet-derived growth factor receptor. (454 aa)
PdgfrbBeta-type platelet-derived growth factor receptor. (528 aa)
AhrAryl hydrocarbon receptor. (247 aa)
Smad4Mothers against decapentaplegic-like 4. (259 aa)
Foxj1Forkhead box protein J1. (421 aa)
Wnt11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
Gli3Zinc finger protein GLI3. (1582 aa)
I79_015033Hairy/enhancer-of-split related with YRPW motif protein 1. (199 aa)
I79_015223Neurogenic locus notch-like protein 2. (248 aa)
I79_015301Nidogen-1. (723 aa)
I79_015321Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (243 aa)
I79_015503Transcription factor HES-1. (92 aa)
Npm3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (337 aa)
Wwtr1WW domain-containing transcription regulator protein 1. (395 aa)
Acat1Acetyl-CoA acetyltransferase, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family. (424 aa)
PdgfbPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (205 aa)
I79_017780Extracellular sulfatase Sulf-1. (787 aa)
Fat4Protocadherin Fat 4. (5152 aa)
Gzf1GDNF-inducible zinc finger protein 1. (701 aa)
I79_018113Nidogen-1. (278 aa)
Aqp11Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (304 aa)
Hnf1bHepatocyte nuclear factor 1-beta. (593 aa)
Tacstd2Tumor-associated calcium signal transducer 2-like protein. (318 aa)
Lgr4Leucine-rich repeat-containing G-protein coupled receptor 4. (231 aa)
Wnt1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
I79_019149Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (132 aa)
Ampd2AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (798 aa)
I79_019507Prominin-1. (565 aa)
Irx2Iroquois-class homeodomain protein IRX-2. (211 aa)
Irx1Iroquois-class homeodomain protein IRX-1. (319 aa)
Tcf21Transcription factor 21. (179 aa)
Lamb2Laminin subunit beta-2. (1800 aa)
I79_021155Paired box protein Pax-2. (503 aa)
I79_021283Angiopoietin-1. (298 aa)
Wnt7bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
Grem1Gremlin-1. (117 aa)
Cd34Hematopoietic progenitor cell antigen CD34. (383 aa)
Mpv17Protein Mpv17; Belongs to the peroxisomal membrane protein PXMP2/4 family. (176 aa)
I79_021721Protocadherin-16. (3015 aa)
Six1Homeobox protein SIX1. (284 aa)
Pax8Paired box protein Pax-8. (452 aa)
I79_022733Kelch-like protein 3. (427 aa)
EnpepGlutamyl aminopeptidase. (372 aa)
I79_023900Leucine zipper putative tumor suppressor 2. (449 aa)
I79_024070Heparan sulfate 2-O-sulfotransferase 1. (224 aa)
Ptch1Protein patched-like 1. (1114 aa)
I79_024202Sal-like protein 1. (825 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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