STRINGSTRING
Pkd1 Pkd1 Greb1 Greb1 Mef2c Mef2c Ext1 Ext1 I79_007229 I79_007229 Lhx1 Lhx1 Ednra Ednra Ctnnb1 Ctnnb1 Kif26b Kif26b I79_006364 I79_006364 Nphs2 Nphs2 I79_006254 I79_006254 I79_006225 I79_006225 Sall1 Sall1 Nog Nog I79_003731 I79_003731 Smo Smo Agt Agt Ahi1 Ahi1 Six2 Six2 I79_000973 I79_000973 Jag1 Jag1 Klf15 Klf15 I79_000180 I79_000180 Gata3 Gata3 ilk ilk Sox8 Sox8 CgPICR_019990 CgPICR_019990 I79_008304 I79_008304 Hoxa11 Hoxa11 Osr1 Osr1 Asxl1 Asxl1 Fgf1 Fgf1 Pgf Pgf I79_009699 I79_009699 I79_009708 I79_009708 Lama5 Lama5 I79_010290 I79_010290 Fmn1 Fmn1 I79_010448 I79_010448 Wnt4 Wnt4 Aqp1 Aqp1 Gdnf Gdnf Pbx1 Pbx1 Magi2 Magi2 I79_011515 I79_011515 I79_011731 I79_011731 Heyl Heyl Podxl Podxl I79_012418 I79_012418 Dll1 Dll1 Notch2 Notch2 H671_2g6716 H671_2g6716 I79_012727 I79_012727 I79_012794 I79_012794 I79_012894 I79_012894 Timeless Timeless Smad4 Smad4 Foxj1 Foxj1 Wnt11 Wnt11 Gli3 Gli3 I79_015033 I79_015033 I79_015223 I79_015223 I79_015321 I79_015321 I79_015503 I79_015503 Npm3 Npm3 Acat1 Acat1 Pdgfb Pdgfb Fat4 Fat4 Gzf1 Gzf1 Aqp11 Aqp11 Hnf1b Hnf1b Tacstd2 Tacstd2 Lgr4 Lgr4 Wnt1 Wnt1 I79_019149 I79_019149 Ampd2 Ampd2 I79_019507 I79_019507 Irx2 Irx2 Irx1 Irx1 Tcf21 Tcf21 Lamb2 Lamb2 I79_021155 I79_021155 Wnt7b Wnt7b Grem1 Grem1 Cd34 Cd34 I79_021721 I79_021721 Six1 Six1 Pax8 Pax8 I79_022733 I79_022733 I79_023900 I79_023900 I79_024070 I79_024070 Ptch1 Ptch1 I79_024202 I79_024202 I79_024203 I79_024203 Ctnnbip1 Ctnnbip1 I79_024483 I79_024483 Umod Umod Mtss1 Mtss1 Commd5 Commd5 Dspp Dspp I79_025625 I79_025625 Wnt9b Wnt9b Myc Myc I79_025974 I79_025974
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Pkd1Polycystin-1. (3717 aa)
Greb1Protein GREB1. (1972 aa)
Mef2cMyocyte-specific enhancer factor 2C. (465 aa)
Ext1Exostosin-1. (388 aa)
I79_007229Receptor-type tyrosine-protein phosphatase O. (1056 aa)
Lhx1LIM/homeobox protein Lhx1. (84 aa)
EdnraEndothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (412 aa)
Ctnnb1Catenin beta-1. (781 aa)
Kif26bKinesin-like protein KIF26B. (189 aa)
I79_006364Kinesin-like protein KIF26B. (158 aa)
Nphs2Podocin. (392 aa)
I79_006254Bone morphogenetic protein 4. (406 aa)
I79_006225Sonic hedgehog protein. (226 aa)
Sall1Sal-like protein 1. (1294 aa)
NogNoggin. (117 aa)
I79_003731Iroquois-class homeodomain protein IRX-3. (341 aa)
SmoSmoothened-like; Belongs to the G-protein coupled receptor Fz/Smo family. (984 aa)
AgtAngiotensinogen; Belongs to the serpin family. (477 aa)
Ahi1Jouberin. (988 aa)
Six2Homeobox protein SIX2. (299 aa)
I79_000973Transcription factor SOX-10. (360 aa)
Jag1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1186 aa)
Klf15Krueppel-like factor 15. (414 aa)
I79_000180Myosin-Ie; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1021 aa)
Gata3Trans-acting T-cell-specific transcription factor GATA-3. (443 aa)
ilkIntegrin-linked protein kinase. (452 aa)
Sox8Transcription factor SOX-8. (463 aa)
CgPICR_019990Persephin. (157 aa)
I79_008304Platelet endothelial cell adhesion molecule. (596 aa)
Hoxa11Homeobox protein Hox-A11. (250 aa)
Osr1Protein odd-skipped-related 1. (266 aa)
Asxl1Putative Polycomb group protein ASXL1. (1470 aa)
Fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
PgfPlacenta growth factor; Belongs to the PDGF/VEGF growth factor family. (154 aa)
I79_009699GREB1-like protein. (1598 aa)
I79_009708Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (332 aa)
Lama5Laminin subunit alpha-5. (3735 aa)
I79_010290Endothelin B receptor; Belongs to the G-protein coupled receptor 1 family. (361 aa)
Fmn1Formin-1. (644 aa)
I79_010448Formin-1. (1049 aa)
Wnt4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (288 aa)
Aqp1Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa)
GdnfGlial cell line-derived neurotrophic factor. (160 aa)
Pbx1Pre-B-cell leukemia transcription factor 1. (325 aa)
Magi2Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2. (483 aa)
I79_011515Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2. (343 aa)
I79_011731Serine/threonine-protein kinase WNK4. (1139 aa)
HeylHairy/enhancer-of-split related with YRPW motif-like protein. (300 aa)
PodxlPodocalyxin-like protein 1. (387 aa)
I79_012418Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2. (120 aa)
Dll1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (741 aa)
Notch2Neurogenic locus notch-like protein 2. (1521 aa)
H671_2g6716Calbindin-like protein. (211 aa)
I79_012727Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (441 aa)
I79_012794Nephrin. (1049 aa)
I79_012894Transcription factor AP-2 beta. (287 aa)
TimelessProtein timeless-like. (1200 aa)
Smad4Mothers against decapentaplegic-like 4. (259 aa)
Foxj1Forkhead box protein J1. (421 aa)
Wnt11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
Gli3Zinc finger protein GLI3. (1582 aa)
I79_015033Hairy/enhancer-of-split related with YRPW motif protein 1. (199 aa)
I79_015223Neurogenic locus notch-like protein 2. (248 aa)
I79_015321Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (243 aa)
I79_015503Transcription factor HES-1. (92 aa)
Npm3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (337 aa)
Acat1Acetyl-CoA acetyltransferase, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family. (424 aa)
PdgfbPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (205 aa)
Fat4Protocadherin Fat 4. (5152 aa)
Gzf1GDNF-inducible zinc finger protein 1. (701 aa)
Aqp11Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (304 aa)
Hnf1bHepatocyte nuclear factor 1-beta. (593 aa)
Tacstd2Tumor-associated calcium signal transducer 2-like protein. (318 aa)
Lgr4Leucine-rich repeat-containing G-protein coupled receptor 4. (231 aa)
Wnt1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
I79_019149Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (132 aa)
Ampd2AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (798 aa)
I79_019507Prominin-1. (565 aa)
Irx2Iroquois-class homeodomain protein IRX-2. (211 aa)
Irx1Iroquois-class homeodomain protein IRX-1. (319 aa)
Tcf21Transcription factor 21. (179 aa)
Lamb2Laminin subunit beta-2. (1800 aa)
I79_021155Paired box protein Pax-2. (503 aa)
Wnt7bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
Grem1Gremlin-1. (117 aa)
Cd34Hematopoietic progenitor cell antigen CD34. (383 aa)
I79_021721Protocadherin-16. (3015 aa)
Six1Homeobox protein SIX1. (284 aa)
Pax8Paired box protein Pax-8. (452 aa)
I79_022733Kelch-like protein 3. (427 aa)
I79_023900Leucine zipper putative tumor suppressor 2. (449 aa)
I79_024070Heparan sulfate 2-O-sulfotransferase 1. (224 aa)
Ptch1Protein patched-like 1. (1114 aa)
I79_024202Sal-like protein 1. (825 aa)
I79_024203Sal-like protein 1. (121 aa)
Ctnnbip1Beta-catenin-interacting protein 1. (81 aa)
I79_024483Polycystin-2. (192 aa)
UmodUromodulin. (618 aa)
Mtss1Metastasis suppressor protein 1. (526 aa)
Commd5COMM domain-containing protein 5. (224 aa)
DsppDentin sialophosphoprotein. (859 aa)
I79_025625Polycystin-2. (318 aa)
Wnt9bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (331 aa)
MycMyc proto-oncogene protein. (281 aa)
I79_025974Metastasis suppressor protein 1. (73 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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