STRINGSTRING
Pgf Pgf I79_015503 I79_015503 Fgf1 Fgf1 Osr1 Osr1 Hoxa11 Hoxa11 CgPICR_019990 CgPICR_019990 Sox8 Sox8 Pkd1 Pkd1 Greb1 Greb1 Lhx1 Lhx1 Ctnnb1 Ctnnb1 Kif26b Kif26b I79_006364 I79_006364 I79_006254 I79_006254 I79_006225 I79_006225 Sall1 Sall1 Nog Nog I79_003731 I79_003731 Agt Agt Ahi1 Ahi1 I79_000973 I79_000973 Gata3 Gata3 ilk ilk I79_015321 I79_015321 I79_015033 I79_015033 Gli3 Gli3 Wnt11 Wnt11 Smad4 Smad4 Timeless Timeless I79_012727 I79_012727 I79_011731 I79_011731 Pbx1 Pbx1 Gdnf Gdnf Wnt4 Wnt4 I79_010448 I79_010448 Fmn1 Fmn1 Lama5 Lama5 I79_009708 I79_009708 Myc Myc Wnt9b Wnt9b I79_025625 I79_025625 Dspp Dspp Commd5 Commd5 I79_024483 I79_024483 Ctnnbip1 Ctnnbip1 I79_024203 I79_024203 I79_024202 I79_024202 Ptch1 Ptch1 I79_024070 I79_024070 I79_023900 I79_023900 I79_022733 I79_022733 Pax8 Pax8 Six1 Six1 I79_021721 I79_021721 Grem1 Grem1 I79_021155 I79_021155 Tcf21 Tcf21 Irx1 Irx1 Irx2 Irx2 I79_019149 I79_019149 Wnt1 Wnt1 Lgr4 Lgr4 Tacstd2 Tacstd2 Hnf1b Hnf1b Gzf1 Gzf1 Fat4 Fat4 Npm3 Npm3 I79_009699 I79_009699
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PgfPlacenta growth factor; Belongs to the PDGF/VEGF growth factor family. (154 aa)
I79_015503Transcription factor HES-1. (92 aa)
Fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
Osr1Protein odd-skipped-related 1. (266 aa)
Hoxa11Homeobox protein Hox-A11. (250 aa)
CgPICR_019990Persephin. (157 aa)
Sox8Transcription factor SOX-8. (463 aa)
Pkd1Polycystin-1. (3717 aa)
Greb1Protein GREB1. (1972 aa)
Lhx1LIM/homeobox protein Lhx1. (84 aa)
Ctnnb1Catenin beta-1. (781 aa)
Kif26bKinesin-like protein KIF26B. (189 aa)
I79_006364Kinesin-like protein KIF26B. (158 aa)
I79_006254Bone morphogenetic protein 4. (406 aa)
I79_006225Sonic hedgehog protein. (226 aa)
Sall1Sal-like protein 1. (1294 aa)
NogNoggin. (117 aa)
I79_003731Iroquois-class homeodomain protein IRX-3. (341 aa)
AgtAngiotensinogen; Belongs to the serpin family. (477 aa)
Ahi1Jouberin. (988 aa)
I79_000973Transcription factor SOX-10. (360 aa)
Gata3Trans-acting T-cell-specific transcription factor GATA-3. (443 aa)
ilkIntegrin-linked protein kinase. (452 aa)
I79_015321Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (243 aa)
I79_015033Hairy/enhancer-of-split related with YRPW motif protein 1. (199 aa)
Gli3Zinc finger protein GLI3. (1582 aa)
Wnt11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
Smad4Mothers against decapentaplegic-like 4. (259 aa)
TimelessProtein timeless-like. (1200 aa)
I79_012727Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (441 aa)
I79_011731Serine/threonine-protein kinase WNK4. (1139 aa)
Pbx1Pre-B-cell leukemia transcription factor 1. (325 aa)
GdnfGlial cell line-derived neurotrophic factor. (160 aa)
Wnt4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (288 aa)
I79_010448Formin-1. (1049 aa)
Fmn1Formin-1. (644 aa)
Lama5Laminin subunit alpha-5. (3735 aa)
I79_009708Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (332 aa)
MycMyc proto-oncogene protein. (281 aa)
Wnt9bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (331 aa)
I79_025625Polycystin-2. (318 aa)
DsppDentin sialophosphoprotein. (859 aa)
Commd5COMM domain-containing protein 5. (224 aa)
I79_024483Polycystin-2. (192 aa)
Ctnnbip1Beta-catenin-interacting protein 1. (81 aa)
I79_024203Sal-like protein 1. (121 aa)
I79_024202Sal-like protein 1. (825 aa)
Ptch1Protein patched-like 1. (1114 aa)
I79_024070Heparan sulfate 2-O-sulfotransferase 1. (224 aa)
I79_023900Leucine zipper putative tumor suppressor 2. (449 aa)
I79_022733Kelch-like protein 3. (427 aa)
Pax8Paired box protein Pax-8. (452 aa)
Six1Homeobox protein SIX1. (284 aa)
I79_021721Protocadherin-16. (3015 aa)
Grem1Gremlin-1. (117 aa)
I79_021155Paired box protein Pax-2. (503 aa)
Tcf21Transcription factor 21. (179 aa)
Irx1Iroquois-class homeodomain protein IRX-1. (319 aa)
Irx2Iroquois-class homeodomain protein IRX-2. (211 aa)
I79_019149Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (132 aa)
Wnt1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
Lgr4Leucine-rich repeat-containing G-protein coupled receptor 4. (231 aa)
Tacstd2Tumor-associated calcium signal transducer 2-like protein. (318 aa)
Hnf1bHepatocyte nuclear factor 1-beta. (593 aa)
Gzf1GDNF-inducible zinc finger protein 1. (701 aa)
Fat4Protocadherin Fat 4. (5152 aa)
Npm3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (337 aa)
I79_009699GREB1-like protein. (1598 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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