(18 nodes) Nephron tubule formation network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	I79_021155	Paired box protein Pax-2. (503 aa)
	Irx1	Iroquois-class homeodomain protein IRX-1. (319 aa)
	Irx2	Iroquois-class homeodomain protein IRX-2. (211 aa)
	Osr1	Protein odd-skipped-related 1. (266 aa)
	Ctnnb1	Catenin beta-1. (781 aa)
	Nog	Noggin. (117 aa)
	Hnf1b	Hepatocyte nuclear factor 1-beta. (593 aa)
	I79_015321	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (243 aa)
	Gata3	Trans-acting T-cell-specific transcription factor GATA-3. (443 aa)
	Sox8	Transcription factor SOX-8. (463 aa)
	Gdnf	Glial cell line-derived neurotrophic factor. (160 aa)
	I79_000973	Transcription factor SOX-10. (360 aa)
	I79_003731	Iroquois-class homeodomain protein IRX-3. (341 aa)
	Wnt9b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (331 aa)
	I79_024070	Heparan sulfate 2-O-sulfotransferase 1. (224 aa)
	Pax8	Paired box protein Pax-8. (452 aa)
	Six1	Homeobox protein SIX1. (284 aa)
	Grem1	Gremlin-1. (117 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ctnnb1	I79_000973	G3H996	G3GTI9	Catenin beta-1.	Transcription factor SOX-10.	0.781
Ctnnb1	I79_015321	G3H996	G3HWG4	Catenin beta-1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.535
Ctnnb1	Sox8	G3H996	G3HBV8	Catenin beta-1.	Transcription factor SOX-8.	0.589
Ctnnb1	Wnt9b	G3H996	G3IP03	Catenin beta-1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.443
Gata3	Pax8	G3GR59	G3IET9	Trans-acting T-cell-specific transcription factor GATA-3.	Paired box protein Pax-8.	0.413
Gdnf	Nog	G3HJV8	G3H1C7	Glial cell line-derived neurotrophic factor.	Noggin.	0.568
Grem1	Nog	G3ID48	G3H1C7	Gremlin-1.	Noggin.	0.479
I79_000973	Ctnnb1	G3GTI9	G3H996	Transcription factor SOX-10.	Catenin beta-1.	0.781
I79_003731	Irx2	G3H0R4	G3I8G3	Iroquois-class homeodomain protein IRX-3.	Iroquois-class homeodomain protein IRX-2.	0.575
I79_015321	Ctnnb1	G3HWG4	G3H996	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Catenin beta-1.	0.535
I79_015321	Wnt9b	G3HWG4	G3IP03	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.554
I79_021155	Six1	G3IBX2	G3IE65	Paired box protein Pax-2.	Homeobox protein SIX1.	0.477
Irx1	Irx2	G3I8J7	G3I8G3	Iroquois-class homeodomain protein IRX-1.	Iroquois-class homeodomain protein IRX-2.	0.465
Irx1	Pax8	G3I8J7	G3IET9	Iroquois-class homeodomain protein IRX-1.	Paired box protein Pax-8.	0.571
Irx2	I79_003731	G3I8G3	G3H0R4	Iroquois-class homeodomain protein IRX-2.	Iroquois-class homeodomain protein IRX-3.	0.575
Irx2	Irx1	G3I8G3	G3I8J7	Iroquois-class homeodomain protein IRX-2.	Iroquois-class homeodomain protein IRX-1.	0.465
Nog	Gdnf	G3H1C7	G3HJV8	Noggin.	Glial cell line-derived neurotrophic factor.	0.568
Nog	Grem1	G3H1C7	G3ID48	Noggin.	Gremlin-1.	0.479
Pax8	Gata3	G3IET9	G3GR59	Paired box protein Pax-8.	Trans-acting T-cell-specific transcription factor GATA-3.	0.413
Pax8	Irx1	G3IET9	G3I8J7	Paired box protein Pax-8.	Iroquois-class homeodomain protein IRX-1.	0.571