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Septin4 | Septin-4; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (204 aa) | ||||
Kdm1a | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (750 aa) | ||||
Kitlg | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa) | ||||
Cd109 | CD109 antigen. (1443 aa) | ||||
Vegfc | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (346 aa) | ||||
Mpl | Thrombopoietin receptor. (647 aa) | ||||
I79_009043 | Microprocessor complex subunit DGCR8. (140 aa) | ||||
I79_009041 | Microprocessor complex subunit DGCR8. (630 aa) | ||||
Taf4b | Transcription initiation factor TFIID subunit 4B. (571 aa) | ||||
Hoxa3 | Homeobox protein Hox-A3. (286 aa) | ||||
Nfatc1 | Nuclear factor of activated T-cells, cytoplasmic 1. (203 aa) | ||||
Nfib | Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (561 aa) | ||||
Runx2 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (365 aa) | ||||
Atxn1l | Ataxin-1-like. (688 aa) | ||||
I79_007190 | Protein argonaute-3. (318 aa) | ||||
I79_007189 | Protein argonaute-3. (202 aa) | ||||
Ncoa3 | Nuclear receptor coactivator 3. (1211 aa) | ||||
I79_006792 | DUF1518 domain-containing protein. (200 aa) | ||||
Hnrnpu | Heterogeneous nuclear ribonucleoprotein U. (512 aa) | ||||
I79_006254 | Bone morphogenetic protein 4. (406 aa) | ||||
I79_006225 | Sonic hedgehog protein. (226 aa) | ||||
I79_005638 | Epithelial cell adhesion molecule. (240 aa) | ||||
Irf6 | Interferon regulatory factor 6. (467 aa) | ||||
Zfp36l1 | Butyrate response factor 1. (338 aa) | ||||
I79_004031 | Fibroblast growth factor receptor. (731 aa) | ||||
I79_002659 | High mobility group protein HMGI-C. (103 aa) | ||||
I79_002496 | Nuclear receptor subfamily 2 group E member 1. (323 aa) | ||||
Cdkn2c | Cyclin-dependent kinase 4 inhibitor C. (168 aa) | ||||
I79_001871 | Transcription factor Ovo-like 2. (213 aa) | ||||
Tgfbr2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) | ||||
I79_001484 | 65 kDa Yes-associated protein. (257 aa) | ||||
Tbx3 | T-box transcription factor TBX3. (709 aa) | ||||
I79_001046 | Neurofibromin. (2164 aa) | ||||
I79_000973 | Transcription factor SOX-10. (360 aa) | ||||
Tp63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (642 aa) | ||||
I79_000445 | Fermitin family-like 1. (641 aa) | ||||
I79_019149 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (132 aa) | ||||
Tgfb1 | Transforming growth factor beta-1. (237 aa) | ||||
Sox18 | Transcription factor SOX-18. (377 aa) | ||||
Tial1 | Nucleolysin TIAR. (353 aa) | ||||
I79_021808 | Putative transcription factor Ovo-like 1. (131 aa) | ||||
I79_022034 | Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1150 aa) | ||||
I79_022667 | Fibulin-1. (628 aa) | ||||
Fbln1 | Fibulin-1. (156 aa) | ||||
I79_023010 | Latent-transforming growth factor beta-binding protein 3. (624 aa) | ||||
Ptch1 | Protein patched-like 1. (1114 aa) | ||||
Irs2 | Insulin receptor substrate 2. (465 aa) | ||||
I79_024415 | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (755 aa) | ||||
I79_025454 | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (182 aa) | ||||
Tert | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (138 aa) | ||||
Wnt10b | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) | ||||
Wnt1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) | ||||
Fermt2 | Fermitin family-like 2. (575 aa) | ||||
Hmx2 | Homeobox protein HMX2. (316 aa) | ||||
Fgf4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (116 aa) | ||||
Ccne1 | G1/S-specific cyclin-E1; Belongs to the cyclin family. (291 aa) | ||||
Cxcl1 | C-X-C motif chemokine. (101 aa) | ||||
I79_016814 | Short stature homeobox protein 2. (194 aa) | ||||
Sfn | 14-3-3 protein sigma; Belongs to the 14-3-3 family. (248 aa) | ||||
Kdf1 | Uncharacterized protein C1orf172-like. (397 aa) | ||||
Npm3 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (337 aa) | ||||
I79_015616 | Interferon-induced, double-stranded RNA-activated protein kinase. (180 aa) | ||||
I79_015181 | 14-3-3 protein sigma; Belongs to the 14-3-3 family. (249 aa) | ||||
Gli3 | Zinc finger protein GLI3. (1582 aa) | ||||
Rarg | Retinoic acid receptor gamma. (458 aa) | ||||
Wnt11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) | ||||
I79_013817 | NAD-dependent deacetylase sirtuin-6. (334 aa) | ||||
Snai2 | Zinc finger protein SNAI2-like protein. (268 aa) | ||||
Prrx1 | Paired mesoderm homeobox protein 1. (198 aa) | ||||
Nf2 | Merlin-like protein. (596 aa) | ||||
Pdcd2 | Programmed cell death protein 2. (708 aa) | ||||
I79_012384 | Leukocyte common antigen. (962 aa) | ||||
I79_011832 | NEDD4-binding protein 2-like 2. (1058 aa) | ||||
Hdac5 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1081 aa) | ||||
Hmgb2 | High mobility group protein B2. (159 aa) | ||||
Pim1 | Proto-oncogene serine/threonine-protein kinase Pim-1. (250 aa) | ||||
I79_010901 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (584 aa) | ||||
Ngf | Beta-nerve growth factor; Belongs to the NGF-beta family. (112 aa) |