(20 nodes) IRES-dependent viral translational initiation network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Pcbp2	Poly(RC)-binding protein 2. (362 aa)
	Mcts1	Malignant T cell amplified sequence 1. (138 aa)
	I79_021191	Density-regulated protein. (54 aa)
	EIF3F	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (260 aa)
	CgPICR_014162	Polypyrimidine tract-binding protein 1. (575 aa)
	I79_006472	Polypyrimidine tract-binding protein 1. (119 aa)
	I79_023431	Polypyrimidine tract-binding protein 1. (323 aa)
	CgPICR_015544	Poly(RC)-binding protein 2. (73 aa)
	Eif3a	Eukaryotic translation initiation factor 3 subunit A. (229 aa)
	I79_006113	Poly(RC)-binding protein 2. (306 aa)
	Eif3b	Eukaryotic translation initiation factor 3 subunit B. (62 aa)
	Ssb	Lupus La protein-like. (407 aa)
	I79_023414	Poly(RC)-binding protein 2. (176 aa)
	Denr	Density-regulated protein; Belongs to the DENR family. (152 aa)
	Eif2d	Ligatin. (590 aa)
	I79_008518	Poly(RC)-binding protein 2. (176 aa)
	Ptbp1	Polypyrimidine tract-binding protein 1. (528 aa)
	I79_010806	Cold shock domain-containing protein E1. (255 aa)
	Csde1	Cold shock domain-containing protein E1. (95 aa)
	Nras	Cold shock domain-containing protein E1. (451 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CgPICR_014162	CgPICR_015544	G3I7U1	G3IHV9	Polypyrimidine tract-binding protein 1.	Poly(RC)-binding protein 2.	0.414
CgPICR_014162	I79_006113	G3I7U1	G3H6Y9	Polypyrimidine tract-binding protein 1.	Poly(RC)-binding protein 2.	0.414
CgPICR_014162	I79_008518	G3I7U1	G3HDH2	Polypyrimidine tract-binding protein 1.	Poly(RC)-binding protein 2.	0.414
CgPICR_014162	I79_023414	G3I7U1	G3IHV7	Polypyrimidine tract-binding protein 1.	Poly(RC)-binding protein 2.	0.414
CgPICR_014162	Pcbp2	G3I7U1	G3HV39	Polypyrimidine tract-binding protein 1.	Poly(RC)-binding protein 2.	0.414
CgPICR_015544	CgPICR_014162	G3IHV9	G3I7U1	Poly(RC)-binding protein 2.	Polypyrimidine tract-binding protein 1.	0.414
CgPICR_015544	I79_006472	G3IHV9	G3H7X6	Poly(RC)-binding protein 2.	Polypyrimidine tract-binding protein 1.	0.414
CgPICR_015544	I79_023431	G3IHV9	G3IHX5	Poly(RC)-binding protein 2.	Polypyrimidine tract-binding protein 1.	0.414
CgPICR_015544	Ptbp1	G3IHV9	G3HF46	Poly(RC)-binding protein 2.	Polypyrimidine tract-binding protein 1.	0.414
Csde1	I79_010806	G3HKJ4	G3HJG1	Cold shock domain-containing protein E1.	Cold shock domain-containing protein E1.	0.908
Denr	Eif2d	G3IC05	G3HAZ8	Density-regulated protein; Belongs to the DENR family.	Ligatin.	0.911
Denr	Eif3a	G3IC05	G3H7R2	Density-regulated protein; Belongs to the DENR family.	Eukaryotic translation initiation factor 3 subunit A.	0.704
Denr	Eif3b	G3IC05	G3GVF4	Density-regulated protein; Belongs to the DENR family.	Eukaryotic translation initiation factor 3 subunit B.	0.712
Denr	Mcts1	G3IC05	G3HYW2	Density-regulated protein; Belongs to the DENR family.	Malignant T cell amplified sequence 1.	0.941
EIF3F	Eif3a	G3I638	G3H7R2	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	Eukaryotic translation initiation factor 3 subunit A.	0.999
EIF3F	Eif3b	G3I638	G3GVF4	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	Eukaryotic translation initiation factor 3 subunit B.	0.999
Eif2d	Denr	G3HAZ8	G3IC05	Ligatin.	Density-regulated protein; Belongs to the DENR family.	0.911
Eif2d	I79_021191	G3HAZ8	G3IC04	Ligatin.	Density-regulated protein.	0.537
Eif2d	Mcts1	G3HAZ8	G3HYW2	Ligatin.	Malignant T cell amplified sequence 1.	0.604
Eif3a	Denr	G3H7R2	G3IC05	Eukaryotic translation initiation factor 3 subunit A.	Density-regulated protein; Belongs to the DENR family.	0.704