(14 nodes) Endothelin receptor signaling pathway network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Cdc42	Cell division control protein 42-like. (191 aa)
	Six1	Homeobox protein SIX1. (284 aa)
	Gnaq	Guanine nucleotide-binding protein G(Q) subunit alpha. (220 aa)
	Edn1	Endothelin-1. (202 aa)
	Gna11	Guanine nucleotide-binding protein subunit alpha-11. (301 aa)
	I79_024904	Guanine nucleotide-binding protein G(Q) subunit alpha. (112 aa)
	I79_024830	Breast cancer anti-estrogen resistance protein 3. (275 aa)
	Crkl	Crk-like protein. (303 aa)
	I79_010290	Endothelin B receptor; Belongs to the G-protein coupled receptor 1 family. (361 aa)
	I79_012336	Protein tyrosine kinase 2 beta. (53 aa)
	Ednra	Endothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (412 aa)
	Bcar1	Breast cancer anti-estrogen resistance protein 1. (879 aa)
	I79_024520	Guanine nucleotide-binding protein subunit alpha-11. (61 aa)
	I79_023421	Breast cancer anti-estrogen resistance protein 3. (253 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bcar1	Cdc42	G3I4P1	G3HIM4	Breast cancer anti-estrogen resistance protein 1.	Cell division control protein 42-like.	0.446
Bcar1	Crkl	G3I4P1	G3HFZ9	Breast cancer anti-estrogen resistance protein 1.	Crk-like protein.	0.985
Bcar1	I79_012336	G3I4P1	G3HNJ8	Breast cancer anti-estrogen resistance protein 1.	Protein tyrosine kinase 2 beta.	0.892
Bcar1	I79_023421	G3I4P1	G3IHW5	Breast cancer anti-estrogen resistance protein 1.	Breast cancer anti-estrogen resistance protein 3.	0.805
Bcar1	I79_024830	G3I4P1	G3ILQ9	Breast cancer anti-estrogen resistance protein 1.	Breast cancer anti-estrogen resistance protein 3.	0.805
Cdc42	Bcar1	G3HIM4	G3I4P1	Cell division control protein 42-like.	Breast cancer anti-estrogen resistance protein 1.	0.446
Cdc42	Crkl	G3HIM4	G3HFZ9	Cell division control protein 42-like.	Crk-like protein.	0.519
Cdc42	I79_012336	G3HIM4	G3HNJ8	Cell division control protein 42-like.	Protein tyrosine kinase 2 beta.	0.586
Crkl	Bcar1	G3HFZ9	G3I4P1	Crk-like protein.	Breast cancer anti-estrogen resistance protein 1.	0.985
Crkl	Cdc42	G3HFZ9	G3HIM4	Crk-like protein.	Cell division control protein 42-like.	0.519
Crkl	I79_012336	G3HFZ9	G3HNJ8	Crk-like protein.	Protein tyrosine kinase 2 beta.	0.557
Edn1	Ednra	G3H0G9	G3H9A8	Endothelin-1.	Endothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family.	0.999
Edn1	Gna11	G3H0G9	G3HSI8	Endothelin-1.	Guanine nucleotide-binding protein subunit alpha-11.	0.406
Edn1	Gnaq	G3H0G9	G3IAG1	Endothelin-1.	Guanine nucleotide-binding protein G(Q) subunit alpha.	0.406
Edn1	I79_010290	G3H0G9	G3HI25	Endothelin-1.	Endothelin B receptor; Belongs to the G-protein coupled receptor 1 family.	0.998
Edn1	I79_024520	G3H0G9	G3IKW6	Endothelin-1.	Guanine nucleotide-binding protein subunit alpha-11.	0.406
Edn1	I79_024904	G3H0G9	G3ILX8	Endothelin-1.	Guanine nucleotide-binding protein G(Q) subunit alpha.	0.406
Ednra	Edn1	G3H9A8	G3H0G9	Endothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family.	Endothelin-1.	0.999
Ednra	Gna11	G3H9A8	G3HSI8	Endothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit alpha-11.	0.943
Ednra	Gnaq	G3H9A8	G3IAG1	Endothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein G(Q) subunit alpha.	0.943