(33 nodes) Regulation of cell migration involved in sprouting angiogenesis network (Cricetulus griseus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Predicted Interactions

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Your Input:
	Srpx2	Sushi repeat-containing protein SRPX2. (283 aa)
	Rhoj	Rho-related GTP-binding protein RhoJ. (170 aa)
	I79_005111	Phosphatidylinositol 3-kinase regulatory subunit beta. (653 aa)
	I79_002496	Nuclear receptor subfamily 2 group E member 1. (323 aa)
	Fgfbp1	Fibroblast growth factor-binding protein 1. (248 aa)
	Cib1	Calcium and integrin-binding protein 1. (191 aa)
	Itgb1bp1	Integrin beta-1-binding protein 1. (199 aa)
	I79_022034	Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1150 aa)
	Hdac7	Histone deacetylase 7. (424 aa)
	Dll4	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (578 aa)
	I79_021045	Heme oxygenase 1. (81 aa)
	Hmox1	Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (290 aa)
	Klf4	Krueppel-like factor 4. (474 aa)
	Anxa1	Annexin. (346 aa)
	Nrp1	Neuropilin; Belongs to the neuropilin family. (923 aa)
	Akt3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	Tbxa2r	Thromboxane A2 receptor-like protein; Belongs to the G-protein coupled receptor 1 family. (339 aa)
	I79_013004	F-box/WD repeat-containing protein 7. (709 aa)
	Ptgs2	Prostaglandin G/H synthase 2. (604 aa)
	Plk2	Serine/threonine-protein kinase PLK. (682 aa)
	Pdcd10	Programmed cell death protein 10. (210 aa)
	Meox2	Homeobox protein MOX-2-like protein. (303 aa)
	Jcad	Uncharacterized protein KIAA1462. (954 aa)
	Pik3c2a	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide; Belongs to the PI3/PI4-kinase family. (637 aa)
	Stard13	StAR-related lipid transfer protein 13. (1113 aa)
	Hdac5	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1081 aa)
	Gata2	Endothelial transcription factor GATA-2. (480 aa)
	Spred1	Sprouty-related, EVH1 domain-containing protein 1. (370 aa)
	Thbs1	Thrombospondin-1. (533 aa)
	Map3k3	Mitogen-activated protein kinase kinase kinase 3. (616 aa)
	Hdac9	Histone deacetylase 9. (576 aa)
	Fbxw9	F-box/WD repeat-containing protein 9. (458 aa)
	Skor1	Dual specificity mitogen-activated protein kinase kinase 5. (719 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Akt3	I79_005111	G3HY42	G3H4B1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 3-kinase regulatory subunit beta.	0.548
Cib1	Plk2	G3IHT6	G3GV10	Calcium and integrin-binding protein 1.	Serine/threonine-protein kinase PLK.	0.424
Dll4	I79_022034	G3ICK3	G3IE90	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.466
Dll4	Nrp1	G3ICK3	G3HZ57	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Neuropilin; Belongs to the neuropilin family.	0.408
Hdac5	I79_002496	G3HLJ3	G3GXK4	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Nuclear receptor subfamily 2 group E member 1.	0.649
Hdac7	Hdac9	G3IE52	G3HD66	Histone deacetylase 7.	Histone deacetylase 9.	0.882
Hdac9	Hdac7	G3HD66	G3IE52	Histone deacetylase 9.	Histone deacetylase 7.	0.882
Hdac9	I79_002496	G3HD66	G3GXK4	Histone deacetylase 9.	Nuclear receptor subfamily 2 group E member 1.	0.454
I79_002496	Hdac5	G3GXK4	G3HLJ3	Nuclear receptor subfamily 2 group E member 1.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.649
I79_002496	Hdac9	G3GXK4	G3HD66	Nuclear receptor subfamily 2 group E member 1.	Histone deacetylase 9.	0.454
I79_005111	Akt3	G3H4B1	G3HY42	Phosphatidylinositol 3-kinase regulatory subunit beta.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.548
I79_005111	I79_022034	G3H4B1	G3IE90	Phosphatidylinositol 3-kinase regulatory subunit beta.	Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.565
I79_005111	Spred1	G3H4B1	G3HHV7	Phosphatidylinositol 3-kinase regulatory subunit beta.	Sprouty-related, EVH1 domain-containing protein 1.	0.574
I79_022034	Dll4	G3IE90	G3ICK3	Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.466
I79_022034	I79_005111	G3IE90	G3H4B1	Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Phosphatidylinositol 3-kinase regulatory subunit beta.	0.565
I79_022034	Nrp1	G3IE90	G3HZ57	Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Neuropilin; Belongs to the neuropilin family.	0.915
I79_022034	Thbs1	G3IE90	G3HHV4	Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Thrombospondin-1.	0.584
Itgb1bp1	Map3k3	G3IHI1	G3HGF0	Integrin beta-1-binding protein 1.	Mitogen-activated protein kinase kinase kinase 3.	0.562
Itgb1bp1	Pdcd10	G3IHI1	G3HQ99	Integrin beta-1-binding protein 1.	Programmed cell death protein 10.	0.603
Map3k3	Itgb1bp1	G3HGF0	G3IHI1	Mitogen-activated protein kinase kinase kinase 3.	Integrin beta-1-binding protein 1.	0.562