STRINGSTRING
I79_016051 I79_016051 Nphp3 Nphp3 Tnn Tnn Sfrp5 Sfrp5 I79_005238 I79_005238 Nog Nog Ptpru Ptpru Isl1 Isl1 I79_004894 I79_004894 Lats1 Lats1 Bicc1 Bicc1 I79_000418 I79_000418 I79_005573 I79_005573 Tmem131l Tmem131l I79_005603 I79_005603 Nkd1 Nkd1 I79_006225 I79_006225 Tle1 Tle1 Dkk1 Dkk1 Axin2 Axin2 Wnt5b Wnt5b I79_006675 I79_006675 Lats2 Lats2 Amer2 Amer2 Hdac1 Hdac1 I79_006923 I79_006923 I79_006924 I79_006924 Ctnnb1 Ctnnb1 Cav1 Cav1 I79_007135 I79_007135 I79_007229 I79_007229 I79_007328 I79_007328 I79_007329 I79_007329 I79_007412 I79_007412 Gsk3b Gsk3b Axin1 Axin1 Egr1 Egr1 Apc Apc Stk11 Stk11 Apc2 Apc2 Siah2 Siah2 I79_009708 I79_009708 I79_009834 I79_009834 Sfrp1 Sfrp1 Hdac2 Hdac2 Amfr Amfr Sox2 Sox2 Wwtr1 Wwtr1 Sostdc1 Sostdc1 Dab2ip Dab2ip Limd1 Limd1 CHD8 CHD8 Dkk3 Dkk3 Ddit3 Ddit3 Gli1 Gli1 I79_014993 I79_014993 I79_014991 I79_014991 Mcc Mcc I79_014914 I79_014914 Gli3 Gli3 Pfdn5 Pfdn5 Wnt11 Wnt11 Mad2l2 Mad2l2 I79_014483 I79_014483 Tmem170b Tmem170b I79_013820 I79_013820 Tle2 Tle2 Tle6 Tle6 Ctnnd1 Ctnnd1 Invs Invs Snai2 Snai2 I79_013059 I79_013059 I79_013013 I79_013013 Apoe Apoe Jade1 Jade1 Stk4 Stk4 Sost Sost Fzd1 Fzd1 Cdh1 Cdh1 Stk3 Stk3 G3bp1 G3bp1 I79_000115 I79_000115 I79_000417 I79_000417 I79_000445 I79_000445 I79_000688 I79_000688 I79_000801 I79_000801 I79_000899 I79_000899 Tpbg Tpbg Slc9a3r1 Slc9a3r1 I79_000973 I79_000973 I79_001457 I79_001457 Wnt5a Wnt5a Sfrp4 Sfrp4 Rbms3 Rbms3 Notum Notum I79_002412 I79_002412 Foxo3 Foxo3 I79_002587 I79_002587 I79_025360 I79_025360 I79_025320 I79_025320 Nkd2 Nkd2 I79_025087 I79_025087 Ctnnbip1 Ctnnbip1 I79_023900 I79_023900 I79_023785 I79_023785 Dkk2 Dkk2 Tcf7l2 Tcf7l2 I79_022994 I79_022994 Prickle1 Prickle1 I79_022484 I79_022484 Shisa3 Shisa3 SDHAF2 SDHAF2 Fzd4 Fzd4 Amer1 Amer1 Grem1 Grem1 Emd Emd I79_020783 I79_020783 I79_019293 I79_019293 Kdm6b Kdm6b Mdk Mdk Fuz Fuz Lmbr1l Lmbr1l I79_018885 I79_018885 Sox10 Sox10 I79_018404 I79_018404 I79_018043 I79_018043 Ccdc88c Ccdc88c Gsk3a Gsk3a I79_016812 I79_016812 Dkkl1 Dkkl1 I79_016646 I79_016646 Foxo1 Foxo1 Mapk14 Mapk14
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_016051Tyrosine-protein kinase transmembrane receptor ROR2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (777 aa)
Nphp3Nephrocystin-3. (542 aa)
TnnTenascin-N. (1552 aa)
Sfrp5Secreted frizzled-related protein 5. (247 aa)
I79_005238RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (193 aa)
NogNoggin. (117 aa)
PtpruReceptor-type tyrosine-protein phosphatase U. (144 aa)
Isl1Insulin gene enhancer protein ISL-1. (257 aa)
I79_004894Transducin-like enhancer protein 3. (642 aa)
Lats1Serine/threonine-protein kinase LATS1. (1130 aa)
Bicc1Protein bicaudal C-like 1. (895 aa)
I79_000418Ras GTPase-activating protein-binding protein 1. (67 aa)
I79_005573Secreted frizzled-related protein 2. (268 aa)
Tmem131lTransmembrane protein 131-like. (1533 aa)
I79_005603Putative ubiquitin carboxyl-terminal hydrolase CYLD. (730 aa)
Nkd1Protein naked cuticle-like 1. (425 aa)
I79_006225Sonic hedgehog protein. (226 aa)
Tle1Transducin-like enhancer protein 1. (95 aa)
Dkk1Dickkopf-related protein 1. (269 aa)
Axin2Axin-2. (809 aa)
Wnt5bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (371 aa)
I79_006675Secreted frizzled-related protein 3. (286 aa)
Lats2Serine/threonine-protein kinase LATS2. (1040 aa)
Amer2Protein FAM123A. (305 aa)
Hdac1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (482 aa)
I79_006923Histone deacetylase 1. (235 aa)
I79_006924Histone deacetylase 1. (188 aa)
Ctnnb1Catenin beta-1. (781 aa)
Cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
I79_007135Homeobox protein Nkx-2.5. (223 aa)
I79_007229Receptor-type tyrosine-protein phosphatase O. (1056 aa)
I79_007328Histone deacetylase 2. (91 aa)
I79_007329Histone deacetylase 1. (250 aa)
I79_007412Transducin-like enhancer protein 2. (327 aa)
Gsk3bGlycogen synthase kinase-3 beta. (328 aa)
Axin1Axin-1. (863 aa)
Egr1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (421 aa)
ApcAdenomatous polyposis coli protein. (2488 aa)
Stk11Serine/threonine-protein kinase 11. (505 aa)
Apc2Adenomatous polyposis coli protein 2. (2236 aa)
Siah2E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (195 aa)
I79_009708Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (332 aa)
I79_009834Disabled-like 2. (705 aa)
Sfrp1Secreted frizzled-related protein 1. (104 aa)
Hdac2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (458 aa)
AmfrAutocrine motility factor receptor. (464 aa)
Sox2Transcription factor SOX-2. (273 aa)
Wwtr1WW domain-containing transcription regulator protein 1. (395 aa)
Sostdc1Sclerostin domain-containing protein 1. (193 aa)
Dab2ipDisabled-like 2-interacting protein. (1065 aa)
Limd1LIM domain-containing protein 1. (667 aa)
CHD8Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2587 aa)
Dkk3Dickkopf-related protein 3. (348 aa)
Ddit3DNA damage-inducible transcript 3. (167 aa)
Gli1Zinc finger protein GLI1. (1104 aa)
I79_014993SCY1-like protein 2. (631 aa)
I79_014991SCY1-like protein 2. (92 aa)
MccColorectal mutant cancer protein. (289 aa)
I79_014914Cadherin-2; Cadherins are calcium-dependent cell adhesion proteins. (756 aa)
Gli3Zinc finger protein GLI3. (1582 aa)
Pfdn5Prefoldin subunit 5. (154 aa)
Wnt11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
Mad2l2Mitotic spindle assembly checkpoint protein MAD2B. (211 aa)
I79_014483Serine/threonine-protein kinase 3. (118 aa)
Tmem170bTransmembrane protein 170B. (99 aa)
I79_013820Amino-terminal enhancer of split. (175 aa)
Tle2Transducin-like enhancer protein 2. (480 aa)
Tle6Transducin-like enhancer protein 6. (530 aa)
Ctnnd1Catenin delta-1. (932 aa)
InvsInversin. (1054 aa)
Snai2Zinc finger protein SNAI2-like protein. (268 aa)
I79_013059FERM domain-containing protein 8. (234 aa)
I79_013013Transcription factor SOX-13. (600 aa)
ApoeApolipoprotein E. (313 aa)
Jade1Protein Jade-1. (834 aa)
Stk4Serine/threonine-protein kinase 4. (487 aa)
SostSclerostin. (213 aa)
Fzd1Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (514 aa)
Cdh1Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. (744 aa)
Stk3Serine/threonine-protein kinase 3. (260 aa)
G3bp1Ras GTPase-activating protein-binding protein 1. (96 aa)
I79_000115Ras GTPase-activating protein-binding protein 1. (258 aa)
I79_000417Ras GTPase-activating protein-binding protein 1. (93 aa)
I79_000445Fermitin family-like 1. (641 aa)
I79_000688Ankyrin repeat domain-containing protein 6. (498 aa)
I79_000801Histone deacetylase 1. (92 aa)
I79_000899T-box transcription factor TBX18. (498 aa)
TpbgTrophoblast glycoprotein. (324 aa)
Slc9a3r1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (354 aa)
I79_000973Transcription factor SOX-10. (360 aa)
I79_001457Ras GTPase-activating protein-binding protein 1. (89 aa)
Wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
Sfrp4Secreted frizzled-related protein 4. (348 aa)
Rbms3RNA-binding motif, single-stranded-interacting protein 3. (381 aa)
NotumProtein notum-like. (354 aa)
I79_002412Protein notum-like. (444 aa)
Foxo3Forkhead box protein O3. (672 aa)
I79_002587Protein AF-9. (347 aa)
I79_025360Draxin. (262 aa)
I79_025320Draxin. (56 aa)
Nkd2Protein naked cuticle-like 2. (417 aa)
I79_025087Trophoblast glycoprotein. (59 aa)
Ctnnbip1Beta-catenin-interacting protein 1. (81 aa)
I79_023900Leucine zipper putative tumor suppressor 2. (449 aa)
I79_023785FERM domain-containing protein 8. (366 aa)
Dkk2Dickkopf-related protein 2. (149 aa)
Tcf7l2Transcription factor 7-like 1. (73 aa)
I79_022994Dapper-like 1. (530 aa)
Prickle1Prickle-like protein 1. (619 aa)
I79_022484Rap guanine nucleotide exchange factor 1. (934 aa)
Shisa3Protein shisa-3-like. (170 aa)
SDHAF2Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer. (120 aa)
Fzd4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (486 aa)
Amer1Protein FAM123B. (1113 aa)
Grem1Gremlin-1. (117 aa)
EmdEmerin. (186 aa)
I79_020783Transcription factor 7-like 2. (451 aa)
I79_019293Protein fuzzy-like. (60 aa)
Kdm6bCytochrome b5 domain-containing protein 1. (173 aa)
MdkMidkine. (160 aa)
FuzProtein fuzzy-like. (365 aa)
Lmbr1lProtein LMBR1L; Belongs to the LIMR family. (489 aa)
I79_018885Transmembrane protein 64. (105 aa)
Sox10Transcription factor SOX-10. (466 aa)
I79_018404Transducin-like enhancer protein 4. (613 aa)
I79_018043Frizzled-6. (109 aa)
Ccdc88cProtein Daple. (225 aa)
Gsk3aGlycogen synthase kinase-3 alpha. (653 aa)
I79_016812Nephrocystin-4. (828 aa)
Dkkl1Dickkopf-like protein 1. (230 aa)
I79_016646RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (518 aa)
Foxo1Forkhead box protein O1. (469 aa)
Mapk14Mitogen-activated protein kinase. (349 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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