(26 nodes) Response to thyroid hormone network (Cricetulus griseus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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Predicted Interactions

gene neighborhood

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Your Input:
	Ctsb	Cathepsin B; Belongs to the peptidase C1 family. (339 aa)
	I79_000449	Cardiolipin synthetase. (233 aa)
	Slc34a1	Sodium-dependent phosphate transport protein 2A. (629 aa)
	Thrb	Thyroid hormone receptor beta. (377 aa)
	Med1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1581 aa)
	Ghsr	Growth hormone secretagogue receptor type 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
	Lmo2	Rhombotin-2. (151 aa)
	Gba	Glucosylceramidase. (515 aa)
	I79_008803	Prestin; Motor protein that converts auditory stimuli to length changes in outer hair cells and mediates sound amplification in the mammalian hearing organ; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (557 aa)
	I79_009151	Bromodomain-containing protein 8. (1040 aa)
	Stk11	Serine/threonine-protein kinase 11. (505 aa)
	Rdx	Radixin. (583 aa)
	Gclc	Glutamate--cysteine ligase catalytic subunit. (584 aa)
	I79_011076	Coagulation factor X. (629 aa)
	Tomm70	Mitochondrial import receptor subunit TOM70. (384 aa)
	Gata1	Erythroid transcription factor-like protein. (330 aa)
	Gas2l1	GAS2-like protein 1. (697 aa)
	Rasl10a	Ras-like protein family member 10A. (232 aa)
	I79_015503	Transcription factor HES-1. (92 aa)
	Ppargc1a	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha. (894 aa)
	I79_016917	Sodium/potassium-transporting ATPase subunit alpha-3; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (632 aa)
	I79_022778	Glutamate--cysteine ligase regulatory subunit. (225 aa)
	I79_023473	Calcium-binding protein 39. (296 aa)
	I79_023814	Arylamine N-acetyltransferase 1; Belongs to the arylamine N-acetyltransferase family. (290 aa)
	Kit	Mast/stem cell growth factor receptor. (452 aa)
	nat	Arylamine N-acetyltransferase 2; Belongs to the arylamine N-acetyltransferase family. (290 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Gas2l1	Rasl10a	G3HP06	G3HP07	GAS2-like protein 1.	Ras-like protein family member 10A.	0.590
Gata1	Lmo2	G3HND3	G3GYY1	Erythroid transcription factor-like protein.	Rhombotin-2.	0.991
Gata1	Med1	G3HND3	G3H5X2	Erythroid transcription factor-like protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.469
Gclc	I79_022778	G3HIY9	G3IG96	Glutamate--cysteine ligase catalytic subunit.	Glutamate--cysteine ligase regulatory subunit.	0.995
I79_022778	Gclc	G3IG96	G3HIY9	Glutamate--cysteine ligase regulatory subunit.	Glutamate--cysteine ligase catalytic subunit.	0.995
I79_023473	Stk11	G3II12	G3HF63	Calcium-binding protein 39.	Serine/threonine-protein kinase 11.	0.976
I79_023814	nat	G3IIY5	Q921C9	Arylamine N-acetyltransferase 1; Belongs to the arylamine N-acetyltransferase family.	Arylamine N-acetyltransferase 2; Belongs to the arylamine N-acetyltransferase family.	0.901
Lmo2	Gata1	G3GYY1	G3HND3	Rhombotin-2.	Erythroid transcription factor-like protein.	0.991
Med1	Gata1	G3H5X2	G3HND3	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Erythroid transcription factor-like protein.	0.469
Med1	Ppargc1a	G3H5X2	G3HWZ1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha.	0.422
Med1	Thrb	G3H5X2	G3H1F7	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Thyroid hormone receptor beta.	0.875
Ppargc1a	Med1	G3HWZ1	G3H5X2	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.422
Rasl10a	Gas2l1	G3HP07	G3HP06	Ras-like protein family member 10A.	GAS2-like protein 1.	0.590
Stk11	I79_023473	G3HF63	G3II12	Serine/threonine-protein kinase 11.	Calcium-binding protein 39.	0.976
Thrb	Med1	G3H1F7	G3H5X2	Thyroid hormone receptor beta.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.875
nat	I79_023814	Q921C9	G3IIY5	Arylamine N-acetyltransferase 2; Belongs to the arylamine N-acetyltransferase family.	Arylamine N-acetyltransferase 1; Belongs to the arylamine N-acetyltransferase family.	0.901