STRINGSTRING
Ide Ide Abca7 Abca7 I79_011940 I79_011940 I79_015046 I79_015046 Lrp1 Lrp1 LDLR LDLR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IdeInsulin-degrading enzyme; Belongs to the peptidase M16 family. (978 aa)
Abca7ATP-binding cassette sub-family A member 7. (408 aa)
I79_011940Platelet glycoprotein 4; Belongs to the CD36 family. (348 aa)
I79_015046Low-density lipoprotein receptor. (160 aa)
Lrp1Prolow-density lipoprotein receptor-related protein 1. (2217 aa)
LDLRLow-density lipoprotein receptor; Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits; Belongs to the LDLR family. (862 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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