47 items (Cricetulus griseus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Akap6	A-kinase anchor protein 6. (1368 aa)
	Kcnj2	Inward rectifier potassium channel 2. (427 aa)
	Nos1	Nitric oxide synthase; Produces nitric oxide (NO). (1413 aa)
	Stc1	Stanniocalcin-1. (247 aa)
	Pde4d	Phosphodiesterase. (507 aa)
	I79_002707	Ran guanine nucleotide release factor. (163 aa)
	Cav3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
	Dbn1	Drebrin. (597 aa)
	I79_004283	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (906 aa)
	Gja5	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
	Tnnt2	Troponin T, cardiac muscle. (215 aa)
	Adora1	Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (326 aa)
	Atp1a2	Sodium/potassium-transporting ATPase subunit alpha-2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1194 aa)
	I79_006562	Voltage-dependent L-type calcium channel subunit alpha-1C. (1112 aa)
	Atp1a1	Sodium/potassium-transporting ATPase subunit alpha. (773 aa)
	Ctnna3	Catenin alpha-3. (95 aa)
	Cav1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
	I79_007363	Catenin alpha-1. (93 aa)
	I79_007364	Catenin alpha-3. (100 aa)
	Fgf13	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (117 aa)
	Cacna1h	Voltage-dependent T-type calcium channel subunit alpha-1H. (2745 aa)
	Dsp	Desmoplakin. (2836 aa)
	I79_008884	Myosin light chain kinase 2, skeletal/cardiac muscle. (747 aa)
	Hcn4	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4. (1033 aa)
	Casq2	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (382 aa)
	Bin1	Myc box-dependent-interacting protein 1. (522 aa)
	Pde4b	Phosphodiesterase. (517 aa)
	Jup	Junction plakoglobin. (1148 aa)
	I79_012424	Ryanodine receptor 2. (2535 aa)
	I79_012425	Ryanodine receptor 2. (2233 aa)
	I79_013214	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1929 aa)
	Acta2	Actin, aortic smooth muscle-like isoform 1. (443 aa)
	Sri	Sorcin. (117 aa)
	I79_015668	Uncharacterized protein. (115 aa)
	Trpm4	Transient receptor potential cation channel subfamily M member 4. (315 aa)
	CgPICR_015426	Ran guanine nucleotide release factor. (154 aa)
	I79_017791	A-kinase anchor protein 9. (3428 aa)
	I79_019510	Desmocollin-2. (370 aa)
	I79_019511	Desmocollin-2; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (430 aa)
	I79_022297	Plakophilin-2. (324 aa)
	Pkp2	Plakophilin-2. (429 aa)
	Ank2	Ankyrin-2. (3299 aa)
	I79_023668	A-kinase anchor protein 9. (79 aa)
	Pdpn	Podoplanin. (55 aa)
	I79_024406	A-kinase anchor protein 6. (211 aa)
	I79_025018	Ankyrin-2. (85 aa)
	I79_026275	A-kinase anchor protein 9. (62 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Acta2	Tnnt2	G3HQY2	G3H3J3	Actin, aortic smooth muscle-like isoform 1.	Troponin T, cardiac muscle.	0.487
Akap6	I79_012424	G3IAI2	G3HNS9	A-kinase anchor protein 6.	Ryanodine receptor 2.	0.488
Akap6	I79_012425	G3IAI2	G3HNT1	A-kinase anchor protein 6.	Ryanodine receptor 2.	0.488
Akap6	I79_024406	G3IAI2	G3IKK3	A-kinase anchor protein 6.	A-kinase anchor protein 6.	0.921
Akap6	Pde4d	G3IAI2	G3GV13	A-kinase anchor protein 6.	Phosphodiesterase.	0.489
Ank2	Trpm4	G3IF65	G3HZZ1	Ankyrin-2.	Transient receptor potential cation channel subfamily M member 4.	0.492
Atp1a1	Atp1a2	G3H8Z9	G3H7Y5	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha-2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	0.916
Atp1a2	Atp1a1	G3H7Y5	G3H8Z9	Sodium/potassium-transporting ATPase subunit alpha-2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	Sodium/potassium-transporting ATPase subunit alpha.	0.916
Bin1	Cav1	G3HKJ6	G3H9I8	Myc box-dependent-interacting protein 1.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.433
Bin1	Dbn1	G3HKJ6	G3H170	Myc box-dependent-interacting protein 1.	Drebrin.	0.496
Cacna1h	Cav3	G3HBW3	G3H113	Voltage-dependent T-type calcium channel subunit alpha-1H.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.653
Cacna1h	Hcn4	G3HBW3	G3HEJ3	Voltage-dependent T-type calcium channel subunit alpha-1H.	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.	0.608
Cacna1h	I79_006562	G3HBW3	G3H863	Voltage-dependent T-type calcium channel subunit alpha-1H.	Voltage-dependent L-type calcium channel subunit alpha-1C.	0.655
Cacna1h	Kcnj2	G3HBW3	G3GTJ0	Voltage-dependent T-type calcium channel subunit alpha-1H.	Inward rectifier potassium channel 2.	0.634
Cacna1h	Nos1	G3HBW3	G3GU55	Voltage-dependent T-type calcium channel subunit alpha-1H.	Nitric oxide synthase; Produces nitric oxide (NO).	0.911
Casq2	Cav3	G3HJF1	G3H113	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.449
Casq2	Hcn4	G3HJF1	G3HEJ3	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.	0.443
Casq2	I79_004283	G3HJF1	G3H239	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	0.487
Casq2	I79_006562	G3HJF1	G3H863	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Voltage-dependent L-type calcium channel subunit alpha-1C.	0.455
Casq2	I79_012424	G3HJF1	G3HNS9	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Ryanodine receptor 2.	0.677