(31 nodes) Positive regulation of sprouting angiogenesis network (Cricetulus griseus)

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query proteins and first shell of interactors

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second shell of interactors

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Predicted Interactions

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Your Input:
	Ghrl	Appetite-regulating hormone. (100 aa)
	Tnn	Tenascin-N. (1552 aa)
	Pkm	Pyruvate kinase; Belongs to the pyruvate kinase family. (472 aa)
	Tjp1	Tight junction protein ZO-1. (762 aa)
	Ghsr	Growth hormone secretagogue receptor type 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
	I79_006225	Sonic hedgehog protein. (226 aa)
	Smad1	Mothers against decapentaplegic-like 1. (232 aa)
	Il10	Interleukin-10. (178 aa)
	I79_007738	Pyruvate kinase isozymes M1/M2. (120 aa)
	Jmjd8	JmjC domain-containing protein 8. (291 aa)
	S100a1	Protein S100; Belongs to the S-100 family. (94 aa)
	Fgf1	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
	I79_010163	Zinc transporter ZIP12. (350 aa)
	I79_010224	BMP-binding endothelial regulator protein. (371 aa)
	Jcad	Uncharacterized protein KIAA1462. (954 aa)
	Dll1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (741 aa)
	Jak1	Tyrosine-protein kinase. (1140 aa)
	I79_016125	Pyruvate kinase isozymes M1/M2. (110 aa)
	Fut2	L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (646 aa)
	Kctd5	3-phosphoinositide-dependent protein kinase 1; Belongs to the peptidase S1 family. (799 aa)
	Itga5	Integrin alpha-5; Belongs to the integrin alpha chain family. (729 aa)
	I79_020424	Pyruvate kinase; Belongs to the pyruvate kinase family. (258 aa)
	Klf4	Krueppel-like factor 4. (474 aa)
	I79_020755	Pyruvate kinase; Belongs to the pyruvate kinase family. (461 aa)
	I79_021938	Mothers against decapentaplegic-like 1. (122 aa)
	I79_023874	Pyruvate kinase; Belongs to the pyruvate kinase family. (233 aa)
	I79_024959	Mothers against decapentaplegic-like 1. (161 aa)
	I79_025316	Mothers against decapentaplegic-like 1. (104 aa)
	I79_025459	Mothers against decapentaplegic-like 1. (117 aa)
	I79_025513	Mothers against decapentaplegic-like 1. (151 aa)
	I79_025783	Mothers against decapentaplegic-like 1. (97 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Fgf1	I79_006225	G3HEK8	G3H796	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	Sonic hedgehog protein.	0.422
Fgf1	Il10	G3HEK8	G3HB01	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	Interleukin-10.	0.463
Ghrl	Ghsr	G3GX43	G3H6H3	Appetite-regulating hormone.	Growth hormone secretagogue receptor type 1; Belongs to the G-protein coupled receptor 1 family.	0.999
Ghsr	Ghrl	G3H6H3	G3GX43	Growth hormone secretagogue receptor type 1; Belongs to the G-protein coupled receptor 1 family.	Appetite-regulating hormone.	0.999
I79_006225	Fgf1	G3H796	G3HEK8	Sonic hedgehog protein.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.422
I79_021938	I79_025316	G3IDZ7	G3IN07	Mothers against decapentaplegic-like 1.	Mothers against decapentaplegic-like 1.	0.638
I79_021938	I79_025459	G3IDZ7	G3INE2	Mothers against decapentaplegic-like 1.	Mothers against decapentaplegic-like 1.	0.893
I79_021938	I79_025783	G3IDZ7	G3IP79	Mothers against decapentaplegic-like 1.	Mothers against decapentaplegic-like 1.	0.563
I79_024959	I79_025316	G3IM29	G3IN07	Mothers against decapentaplegic-like 1.	Mothers against decapentaplegic-like 1.	0.611
I79_024959	I79_025459	G3IM29	G3INE2	Mothers against decapentaplegic-like 1.	Mothers against decapentaplegic-like 1.	0.900
I79_024959	I79_025783	G3IM29	G3IP79	Mothers against decapentaplegic-like 1.	Mothers against decapentaplegic-like 1.	0.545
I79_025316	I79_021938	G3IN07	G3IDZ7	Mothers against decapentaplegic-like 1.	Mothers against decapentaplegic-like 1.	0.638
I79_025316	I79_024959	G3IN07	G3IM29	Mothers against decapentaplegic-like 1.	Mothers against decapentaplegic-like 1.	0.611
I79_025316	I79_025459	G3IN07	G3INE2	Mothers against decapentaplegic-like 1.	Mothers against decapentaplegic-like 1.	0.764
I79_025316	I79_025513	G3IN07	G3INI8	Mothers against decapentaplegic-like 1.	Mothers against decapentaplegic-like 1.	0.627
I79_025459	I79_021938	G3INE2	G3IDZ7	Mothers against decapentaplegic-like 1.	Mothers against decapentaplegic-like 1.	0.893
I79_025459	I79_024959	G3INE2	G3IM29	Mothers against decapentaplegic-like 1.	Mothers against decapentaplegic-like 1.	0.900
I79_025459	I79_025316	G3INE2	G3IN07	Mothers against decapentaplegic-like 1.	Mothers against decapentaplegic-like 1.	0.764
I79_025459	I79_025513	G3INE2	G3INI8	Mothers against decapentaplegic-like 1.	Mothers against decapentaplegic-like 1.	0.902
I79_025459	I79_025783	G3INE2	G3IP79	Mothers against decapentaplegic-like 1.	Mothers against decapentaplegic-like 1.	0.646