7 items (Cricetulus griseus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Plcg2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1199 aa)
	Akt1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	I79_005032	DDRGK domain-containing protein 1. (345 aa)
	Cx3cl1	Fractalkine. (335 aa)
	Cx3cr1	CX3C chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa)
	Tnf	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (234 aa)
	Traf2	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Akt1	Plcg2	G3H397	G3GRN8	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.474
Akt1	Tnf	G3H397	G3HZG9	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.636
Akt1	Traf2	G3H397	G3IHB5	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.451
Cx3cl1	Cx3cr1	G3HIL2	G3HQW7	Fractalkine.	CX3C chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.999
Cx3cl1	Tnf	G3HIL2	G3HZG9	Fractalkine.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.460
Cx3cr1	Cx3cl1	G3HQW7	G3HIL2	CX3C chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family.	Fractalkine.	0.999
Cx3cr1	Tnf	G3HQW7	G3HZG9	CX3C chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.603
Plcg2	Akt1	G3GRN8	G3H397	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.474
Tnf	Akt1	G3HZG9	G3H397	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.636
Tnf	Cx3cl1	G3HZG9	G3HIL2	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	Fractalkine.	0.460
Tnf	Cx3cr1	G3HZG9	G3HQW7	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	CX3C chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.603
Tnf	Traf2	G3HZG9	G3IHB5	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.974
Traf2	Akt1	G3IHB5	G3H397	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.451
Traf2	Tnf	G3IHB5	G3HZG9	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.974