STRINGSTRING
I79_023775 I79_023775 I79_023921 I79_023921 Dmrt1 Dmrt1 I79_024210 I79_024210 Serpinf1 Serpinf1 Trip13 Trip13 P2ry2 P2ry2 I79_024944 I79_024944 I79_024946 I79_024946 Nppc Nppc Kit Kit Tacr3 Tacr3 Acvr1b Acvr1b I79_026091 I79_026091 Gpr3 Gpr3 Jag1 Jag1 I79_000439 I79_000439 I79_000677 I79_000677 I79_000973 I79_000973 Vip Vip Fbxo5 Fbxo5 I79_001328 I79_001328 I79_001367 I79_001367 Wnt5a Wnt5a Mmp12 Mmp12 Rac1 Rac1 Lfng Lfng I79_002010 I79_002010 Msx1 Msx1 Pla2g10 Pla2g10 I79_002178 I79_002178 I79_002454 I79_002454 Src Src C1qbp C1qbp I79_003180 I79_003180 Tacr1 Tacr1 Oxtr Oxtr Msx2 Msx2 Hoxd13 Hoxd13 Ythdf2 Ythdf2 Ptafr Ptafr Gdf9 Gdf9 Il18 Il18 Lhfpl2 Lhfpl2 Rgn Rgn Cdc25b Cdc25b Insl3 Insl3 Glra1 Glra1 Igf1 Igf1 Nodal Nodal Tacr2 Tacr2 Ttk Ttk I79_006225 I79_006225 I79_006234 I79_006234 I79_006254 I79_006254 Shb Shb Iqcf1 Iqcf1 Iho1 Iho1 Ctnnb1 Ctnnb1 I79_007067 I79_007067 Dusp1 Dusp1 Zp3 Zp3 Eaf2 Eaf2 Cdkn1b Cdkn1b Bmp7 Bmp7 Aurka Aurka Cacna1h Cacna1h I79_008145 I79_008145 I79_008298 I79_008298 Calr Calr Prkaca Prkaca Sgo2 Sgo2 Rspo1 Rspo1 H671_5g13635 H671_5g13635 I79_009001 I79_009001 Snai1 Snai1 I79_009148 I79_009148 Apc Apc Stk11 Stk11 Cdc20 Cdc20 Itgb3 Itgb3 Wee2 Wee2 I79_009916 I79_009916 Ooep Ooep I79_010073 I79_010073 Dkk4 Dkk4 Sfrp1 Sfrp1 I79_010194 I79_010194 Hdac2 Hdac2 I79_010290 I79_010290 Wnt4 Wnt4 I79_010674 I79_010674 Sirt2 Sirt2 Tac4 Tac4 I79_011051 I79_011051 Stk3 Stk3 Rad1 Rad1 Igf1r Igf1r I79_011284 I79_011284 Cdc25a Cdc25a I79_011297 I79_011297 I79_011465 I79_011465 H671_1g3121 H671_1g3121 P2ry1 P2ry1 Umodl1 Umodl1 Ada Ada Stk4 Stk4 I79_011725 I79_011725 Cntd1 Cntd1 I79_011753 I79_011753 Aspm Aspm Syde1 Syde1 I79_011859 I79_011859 Prkacb Prkacb Npr2 Npr2 Sema3a Sema3a H671_3g9571 H671_3g9571 Runx1 Runx1 I79_012666 I79_012666 Nanos2 Nanos2 Crisp1 Crisp1 Ythdf3 Ythdf3 I79_013201 I79_013201 Tcp11 Tcp11 Grb14 Grb14 Fzr1 Fzr1 Tpst2 Tpst2 Fbxo43 Fbxo43 I79_014483 I79_014483 Stxbp1 Stxbp1 Hoxc4 Hoxc4 Inhba Inhba Ythdc2 Ythdc2 I79_015386 I79_015386 Tppp2 Tppp2 Mettl3 Mettl3 Insr Insr I79_015653 I79_015653 Ankrd31 Ankrd31 Gpr149 Gpr149 Hdac4 Hdac4 I79_016287 I79_016287 I79_016931 I79_016931 Dhx37 Dhx37 Lif Lif Osm Osm Rnase10 Rnase10 Rnase9 Rnase9 Ppp2r1a Ppp2r1a Mos Mos I79_017780 I79_017780 Bnc1 Bnc1 I79_017795 I79_017795 Drd4 Drd4 Eif4g3 Eif4g3 Ccr6 Ccr6 Ccdc87 Ccdc87 Anxa5 Anxa5 Gcm1 Gcm1 I79_018988 I79_018988 I79_019286 I79_019286 AGO2 AGO2 Fbxo42 Fbxo42 Prdm14 Prdm14 B4galt1 B4galt1 I79_020009 I79_020009 I79_020063 I79_020063 Nr5a1 Nr5a1 Timp1 Timp1 I79_021595 I79_021595 I79_021808 I79_021808 Rxra Rxra I79_021943 I79_021943 Zp1 Zp1 I79_022271 I79_022271 Pkdrej Pkdrej Ar Ar I79_023145 I79_023145 Cib1 Cib1 Ddb1 Ddb1 I79_023569 I79_023569 Ovgp1 Ovgp1 Mfn2 Mfn2 Phlda2 Phlda2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_023775Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (256 aa)
I79_023921Trichosurin; Belongs to the calycin superfamily. Lipocalin family. (212 aa)
Dmrt1Doublesex-and mab-3-related transcription factor 1. (158 aa)
I79_024210Nuclear protein 1. (103 aa)
Serpinf1Pigment epithelium-derived factor; Belongs to the serpin family. (94 aa)
Trip13Thyroid receptor-interacting protein 13; Belongs to the AAA ATPase family. (404 aa)
P2ry2p2Y purinoceptor 2; Belongs to the G-protein coupled receptor 1 family. (151 aa)
I79_024944NACHT, LRR and PYD domains-containing protein 5. (98 aa)
I79_024946NACHT, LRR and PYD domains-containing protein 5. (626 aa)
NppcC-type natriuretic peptide. (126 aa)
KitMast/stem cell growth factor receptor. (452 aa)
Tacr3Neuromedin-K receptor. (166 aa)
Acvr1bReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (373 aa)
I79_026091Pigment epithelium-derived factor; Belongs to the serpin family. (58 aa)
Gpr3G-protein coupled receptor 3; Belongs to the G-protein coupled receptor 1 family. (213 aa)
Jag1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1186 aa)
I79_000439Phosphoinositide phospholipase C. (949 aa)
I79_000677Cannabinoid receptor 1; Belongs to the G-protein coupled receptor 1 family. (415 aa)
I79_000973Transcription factor SOX-10. (360 aa)
VipVIP peptides. (170 aa)
Fbxo5F-box only protein 5. (388 aa)
I79_001328NACHT, LRR and PYD domains-containing protein 5. (160 aa)
I79_001367RAD51-associated protein 1. (336 aa)
Wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
Mmp12Macrophage metalloelastase. (464 aa)
Rac1Ras-related C3 botulinum toxin substrate 1. (148 aa)
LfngBeta-1,3-N-acetylglucosaminyltransferase. (378 aa)
I79_002010Phospholipase B1, membrane-associated. (995 aa)
Msx1Homeobox protein MSX-1. (261 aa)
Pla2g10Phospholipase A(2). (140 aa)
I79_002178Urokinase-type plasminogen activator; Belongs to the peptidase S1 family. (397 aa)
I79_002454Lanosterol 14-alpha demethylase; Belongs to the cytochrome P450 family. (503 aa)
SrcTyrosine-protein kinase. (536 aa)
C1qbpComplement component 1 Q subcomponent-binding protein, mitochondrial. (209 aa)
I79_003180Disintegrin and metalloproteinase domain-containing protein 24. (694 aa)
Tacr1Substance-P receptor; Belongs to the G-protein coupled receptor 1 family. (407 aa)
OxtrOxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (353 aa)
Msx2Homeobox protein MSX-2. (267 aa)
Hoxd13Homeobox protein Hox-D13. (204 aa)
Ythdf2YTH domain family protein 2. (529 aa)
PtafrPlatelet-activating factor receptor; Belongs to the G-protein coupled receptor 1 family. (341 aa)
Gdf9Growth/differentiation factor 9. (258 aa)
Il18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (196 aa)
Lhfpl2Lipoma HMGIC fusion partner-like 2 protein. (209 aa)
RgnRegucalcin. (265 aa)
Cdc25bM-phase inducer phosphatase 2. (480 aa)
Insl3Insulin-like 3-like protein. (126 aa)
Glra1Glycine receptor subunit alpha-1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (413 aa)
Igf1Insulin-like growth factor I. (75 aa)
NodalNodal. (309 aa)
Tacr2Substance-K receptor. (320 aa)
TtkDual specificity protein kinase TTK. (57 aa)
I79_006225Sonic hedgehog protein. (226 aa)
I79_006234Syntaxin-binding protein 1; Belongs to the STXBP/unc-18/SEC1 family. (161 aa)
I79_006254Bone morphogenetic protein 4. (406 aa)
ShbSH2 domain-containing adapter protein B. (298 aa)
Iqcf1IQ domain-containing protein F1. (141 aa)
Iho1Coiled-coil domain-containing protein 36. (598 aa)
Ctnnb1Catenin beta-1. (781 aa)
I79_007067Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1107 aa)
Dusp1Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa)
Zp3Zona pellucida sperm-binding protein 3. (403 aa)
Eaf2ELL-associated factor 2. (81 aa)
Cdkn1bCyclin-dependent kinase inhibitor 1B. (198 aa)
Bmp7Bone morphogenetic protein 7. (430 aa)
AurkaSerine/threonine-protein kinase 6; Belongs to the protein kinase superfamily. (386 aa)
Cacna1hVoltage-dependent T-type calcium channel subunit alpha-1H. (2745 aa)
I79_008145Zinc finger protein 605. (769 aa)
I79_008298E3 ubiquitin-protein ligase SMURF2. (571 aa)
CalrCalreticulin. (417 aa)
PrkacacAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
Sgo2Shugoshin-like 2. (1156 aa)
Rspo1R-spondin-1. (262 aa)
H671_5g13635Protein maelstrom-like. (172 aa)
I79_009001Zinc finger protein ZFPM2. (718 aa)
Snai1Zinc finger protein SNAI1-like protein. (264 aa)
I79_009148M-phase inducer phosphatase 3. (319 aa)
ApcAdenomatous polyposis coli protein. (2488 aa)
Stk11Serine/threonine-protein kinase 11. (505 aa)
Cdc20Cell division cycle protein 20-like. (499 aa)
Itgb3Integrin beta; Belongs to the integrin beta chain family. (975 aa)
Wee2Wee1-like protein kinase 2. (249 aa)
I79_009916Phosphodiesterase. (693 aa)
OoepOocyte-expressed protein-like. (129 aa)
I79_010073Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (511 aa)
Dkk4Salivary plasminogen activator alpha 2. (675 aa)
Sfrp1Secreted frizzled-related protein 1. (104 aa)
I79_010194Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (387 aa)
Hdac2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (458 aa)
I79_010290Endothelin B receptor; Belongs to the G-protein coupled receptor 1 family. (361 aa)
Wnt4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (288 aa)
I79_010674UPF0704 protein C6orf165-like. (502 aa)
Sirt2NAD-dependent deacetylase sirtuin-2. (83 aa)
Tac4Tachykinin-4. (127 aa)
I79_011051Non-specific serine/threonine protein kinase. (644 aa)
Stk3Serine/threonine-protein kinase 3. (260 aa)
Rad1Cell cycle checkpoint protein RAD1. (279 aa)
Igf1rInsulin-like growth factor 1 receptor. (191 aa)
I79_011284M-phase inducer phosphatase 1. (307 aa)
Cdc25aM-phase inducer phosphatase 1. (121 aa)
I79_011297Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (878 aa)
I79_011465Uncharacterized protein C7orf63-like. (194 aa)
H671_1g3121Armadillo-type fold containing protein. (388 aa)
P2ry1p2Y purinoceptor 1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
Umodl1Uromodulin-like 1. (1351 aa)
AdaAdenosine deaminase. (363 aa)
Stk4Serine/threonine-protein kinase 4. (487 aa)
I79_011725Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (249 aa)
Cntd1CNTD1. (328 aa)
I79_011753Abnormal spindle-like microcephaly-associated protein-like. (416 aa)
AspmAbnormal spindle-like microcephaly-associated protein-like. (1831 aa)
Syde1Rho GTPase-activating protein SYDE1. (736 aa)
I79_011859Calcium/calmodulin-dependent protein kinase type II beta chain. (337 aa)
PrkacbcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
Npr2Guanylate cyclase. (663 aa)
Sema3aSemaphorin-3A-like protein; Belongs to the semaphorin family. (758 aa)
H671_3g9571Zona pellucida sperm-binding protein 4. (454 aa)
Runx1Runt-related transcription factor 1. (462 aa)
I79_012666Hepatocyte nuclear factor 3-gamma. (594 aa)
Nanos2Nanos-like 2; Belongs to the nanos family. (132 aa)
Crisp1Cysteine-rich secretory protein 1. (124 aa)
Ythdf3YTH domain family protein 3. (588 aa)
I79_013201EF-hand calcium-binding domain-containing protein 1. (151 aa)
Tcp11T-complex protein 11-like. (379 aa)
Grb14Growth factor receptor-bound protein 14. (466 aa)
Fzr1Fizzy-related protein-like. (493 aa)
Tpst2Protein-tyrosine sulfotransferase; Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate; Belongs to the protein sulfotransferase family. (390 aa)
Fbxo43F-box only protein 43. (1330 aa)
I79_014483Serine/threonine-protein kinase 3. (118 aa)
Stxbp1Syntaxin-binding protein 1; Belongs to the STXBP/unc-18/SEC1 family. (385 aa)
Hoxc4Homeobox protein Hox-C4. (56 aa)
InhbaInhibin beta A chain-like protein. (424 aa)
Ythdc2Putative ATP-dependent RNA helicase YTHDC2. (1268 aa)
I79_015386Mitogen-activated protein kinase 15. (635 aa)
Tppp2Tubulin polymerization-promoting protein family member 2-like protein. (170 aa)
Mettl3N6-adenosine-methyltransferase 70 kDa subunit; Belongs to the MT-A70-like family. (580 aa)
InsrInsulin receptor. (114 aa)
I79_015653T-complex protein 11-like. (294 aa)
Ankrd31Ankyrin repeat domain-containing protein 31. (319 aa)
Gpr149Putative G-protein coupled receptor 149. (541 aa)
Hdac4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (966 aa)
I79_016287Testis-expressed protein 101. (448 aa)
I79_016931Stimulated by retinoic acid gene 8 protein. (269 aa)
Dhx37Putative ATP-dependent RNA helicase DHX37. (319 aa)
LifLeukemia inhibitory factor-like protein. (158 aa)
OsmOncostatin-M. (222 aa)
Rnase10Ribonuclease-like protein 10; Belongs to the pancreatic ribonuclease family. (206 aa)
Rnase9Ribonuclease-like protein 9; Belongs to the pancreatic ribonuclease family. (186 aa)
Ppp2r1aSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (534 aa)
MosSerine/threonine-protein kinase-transforming protein mos. (203 aa)
I79_017780Extracellular sulfatase Sulf-1. (787 aa)
Bnc1Zinc finger protein basonuclin-1. (834 aa)
I79_017795Zinc finger protein basonuclin-1. (76 aa)
Drd4D(4) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (387 aa)
Eif4g3Eukaryotic translation initiation factor 4 gamma 3. (1578 aa)
Ccr6C-C chemokine receptor type 6; Belongs to the G-protein coupled receptor 1 family. (367 aa)
Ccdc87Coiled-coil domain-containing protein 87. (861 aa)
Anxa5Annexin. (321 aa)
Gcm1Chorion-specific transcription factor GCMa. (436 aa)
I79_018988Zonadhesin. (4512 aa)
I79_019286Androgen receptor. (295 aa)
AGO2Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (813 aa)
Fbxo42F-box only protein 42. (624 aa)
Prdm14PR domain zinc finger protein 14. (564 aa)
B4galt1Beta-1,4-galactosyltransferase 1. (258 aa)
I79_020009Phosphodiesterase. (597 aa)
I79_020063M-phase inducer phosphatase 3. (284 aa)
Nr5a1Steroidogenic factor 1. (462 aa)
Timp1Metalloproteinase inhibitor 1-like protein. (203 aa)
I79_021595Neuromedin-K receptor; Belongs to the G-protein coupled receptor 1 family. (231 aa)
I79_021808Putative transcription factor Ovo-like 1. (131 aa)
RxraRetinoic acid receptor RXR-alpha. (439 aa)
I79_021943Putative G-protein coupled receptor 44; Belongs to the G-protein coupled receptor 1 family. (376 aa)
Zp1Zona pellucida sperm-binding protein 1. (626 aa)
I79_022271Ras-related C3 botulinum toxin substrate 2. (178 aa)
PkdrejPolycystic kidney disease and receptor for egg jelly-related protein. (2135 aa)
ArAndrogen receptor. (517 aa)
I79_023145Myosin-9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1948 aa)
Cib1Calcium and integrin-binding protein 1. (191 aa)
Ddb1DNA damage-binding protein 1. (1140 aa)
I79_023569Methylosome protein 50. (283 aa)
Ovgp1Oviduct-specific glycoprotein. (615 aa)
Mfn2Mitofusin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
Phlda2Pleckstrin-likey-like domain family A member 2. (134 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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