STRINGSTRING
I79_007297 I79_007297 Angptl4 Angptl4 Scg2 Scg2 I79_021283 I79_021283 Gas6 Gas6 ICAM1 ICAM1 Tert Tert I79_025454 I79_025454 I79_024415 I79_024415 Abl1 Abl1 I79_022034 I79_022034 Gata3 Gata3 I79_009740 I79_009740 I79_009958 I79_009958 Gata2 Gata2 Pak4 Pak4 Ndnf Ndnf Abl2 Abl2 Fgf21 Fgf21 Tnip2 Tnip2 Kctd5 Kctd5 I79_007548 I79_007548 Il10 Il10 I79_001733 I79_001733 Tnfaip3 Tnfaip3 Krit1 Krit1 Nfe2l2 Nfe2l2 Fga Fga Fgb Fgb Cdh5 Cdh5 Sema5a Sema5a Serpine1 Serpine1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_007297Plasminogen activator inhibitor 1; Belongs to the serpin family. (108 aa)
Angptl4Angiopoietin-related protein 4. (411 aa)
Scg2Secretogranin-2. (763 aa)
I79_021283Angiopoietin-1. (298 aa)
Gas6Growth arrest-specific protein 6. (684 aa)
ICAM1Intercellular adhesion molecule 1. (527 aa)
TertTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (138 aa)
I79_025454Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (182 aa)
I79_024415Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (755 aa)
Abl1Tyrosine-protein kinase transforming protein Abl. (322 aa)
I79_022034Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1150 aa)
Gata3Trans-acting T-cell-specific transcription factor GATA-3. (443 aa)
I79_009740B-Raf proto-oncogene serine/threonine-protein kinase. (229 aa)
I79_009958Angiopoietin-1 receptor. (793 aa)
Gata2Endothelial transcription factor GATA-2. (480 aa)
Pak4Non-specific serine/threonine protein kinase. (588 aa)
NdnfFibronectin type-III domain-containing protein C4orf31-like. (567 aa)
Abl2Tyrosine-protein kinase. (1167 aa)
Fgf21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
Tnip2TNFAIP3-interacting protein 2. (431 aa)
Kctd53-phosphoinositide-dependent protein kinase 1; Belongs to the peptidase S1 family. (799 aa)
I79_007548Angiopoietin-1. (112 aa)
Il10Interleukin-10. (178 aa)
I79_001733Mitogen-activated protein kinase. (1186 aa)
Tnfaip3Tumor necrosis factor, alpha-induced protein 3. (776 aa)
Krit1Krev interaction trapped protein 1. (740 aa)
Nfe2l2Nuclear factor erythroid 2-related factor 2. (588 aa)
FgaFibrinogen alpha chain. (1209 aa)
FgbFibrinogen beta chain. (407 aa)
Cdh5Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins. (763 aa)
Sema5aSemaphorin-5A. (1046 aa)
Serpine1Plasminogen activator inhibitor 1; Belongs to the serpin family. (270 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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