(29 nodes) Regulation of cardiac muscle cell differentiation network (Cricetulus griseus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

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protein homology

Your Input:
	Smad4	Mothers against decapentaplegic-like 4. (259 aa)
	I79_026231	Ephrin-B2; Belongs to the ephrin family. (68 aa)
	I79_025726	Ephrin-B2. (121 aa)
	I79_025535	Ephrin-B2. (125 aa)
	I79_025518	Ephrin-B2. (123 aa)
	I79_025497	Ephrin-B2; Belongs to the ephrin family. (69 aa)
	I79_025496	Ephrin-B2. (147 aa)
	I79_025433	Ephrin-B2; Belongs to the ephrin family. (70 aa)
	I79_024975	Ephrin-B2. (148 aa)
	Grem1	Gremlin-1. (117 aa)
	I79_021151	Ephrin-B2. (178 aa)
	Tgfb1	Transforming growth factor beta-1. (237 aa)
	Frs2	Fibroblast growth factor receptor substrate 2. (509 aa)
	I79_014451	Pro-neuregulin-1, membrane-bound isoform. (639 aa)
	I79_013907	Ephrin-B2. (148 aa)
	Dll1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (741 aa)
	I79_011919	Transcription factor SOX-6. (237 aa)
	I79_011918	Transcription factor Sox-6. (395 aa)
	Kat2a	Histone acetyltransferase KAT2A. (663 aa)
	I79_010136	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (230 aa)
	Mef2c	Myocyte-specific enhancer factor 2C. (465 aa)
	Gsk3b	Glycogen synthase kinase-3 beta. (328 aa)
	Dkk1	Dickkopf-related protein 1. (269 aa)
	I79_006254	Bone morphogenetic protein 4. (406 aa)
	I79_003100	Myocardin. (371 aa)
	Fzd7	Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (438 aa)
	I79_002785	Beta-arrestin-2. (65 aa)
	Ccnd2	G1/S-specific cyclin-D2; Belongs to the cyclin family. (288 aa)
	I79_001024	Ephrin-B2; Belongs to the ephrin family. (373 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ccnd2	Gsk3b	G3GUJ9	G3HAI0	G1/S-specific cyclin-D2; Belongs to the cyclin family.	Glycogen synthase kinase-3 beta.	0.933
Dkk1	Gsk3b	G3H7W8	G3HAI0	Dickkopf-related protein 1.	Glycogen synthase kinase-3 beta.	0.437
Dkk1	I79_006254	G3H7W8	G3H7C4	Dickkopf-related protein 1.	Bone morphogenetic protein 4.	0.431
Dkk1	I79_010136	G3H7W8	G3HHN2	Dickkopf-related protein 1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.589
Fzd7	Gsk3b	G3GYW8	G3HAI0	Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family.	Glycogen synthase kinase-3 beta.	0.458
Fzd7	I79_010136	G3GYW8	G3HHN2	Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.697
Grem1	I79_006254	G3ID48	G3H7C4	Gremlin-1.	Bone morphogenetic protein 4.	0.618
Gsk3b	Ccnd2	G3HAI0	G3GUJ9	Glycogen synthase kinase-3 beta.	G1/S-specific cyclin-D2; Belongs to the cyclin family.	0.933
Gsk3b	Dkk1	G3HAI0	G3H7W8	Glycogen synthase kinase-3 beta.	Dickkopf-related protein 1.	0.437
Gsk3b	Fzd7	G3HAI0	G3GYW8	Glycogen synthase kinase-3 beta.	Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family.	0.458
Gsk3b	I79_002785	G3HAI0	G3GYB1	Glycogen synthase kinase-3 beta.	Beta-arrestin-2.	0.443
Gsk3b	I79_006254	G3HAI0	G3H7C4	Glycogen synthase kinase-3 beta.	Bone morphogenetic protein 4.	0.406
Gsk3b	I79_010136	G3HAI0	G3HHN2	Glycogen synthase kinase-3 beta.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.690
Gsk3b	Smad4	G3HAI0	G3HTR4	Glycogen synthase kinase-3 beta.	Mothers against decapentaplegic-like 4.	0.417
Gsk3b	Tgfb1	G3HAI0	G3IA12	Glycogen synthase kinase-3 beta.	Transforming growth factor beta-1.	0.469
I79_002785	Gsk3b	G3GYB1	G3HAI0	Beta-arrestin-2.	Glycogen synthase kinase-3 beta.	0.443
I79_003100	Mef2c	G3GZ48	G3HAW1	Myocardin.	Myocyte-specific enhancer factor 2C.	0.564
I79_006254	Dkk1	G3H7C4	G3H7W8	Bone morphogenetic protein 4.	Dickkopf-related protein 1.	0.431
I79_006254	Grem1	G3H7C4	G3ID48	Bone morphogenetic protein 4.	Gremlin-1.	0.618
I79_006254	Gsk3b	G3H7C4	G3HAI0	Bone morphogenetic protein 4.	Glycogen synthase kinase-3 beta.	0.406