STRINGSTRING
I79_014483 I79_014483 I79_005603 I79_005603 Jak3 Jak3 I79_005129 I79_005129 Siglec1 Siglec1 Ppp2r1b Ppp2r1b I79_003765 I79_003765 Ppp1ca Ppp1ca I79_018257 I79_018257 Agtr2 Agtr2 I79_018586 I79_018586 I79_019425 I79_019425 Htra2 Htra2 Rbck1 Rbck1 Atf3 Atf3 I79_022080 I79_022080 Ripk1 Ripk1 I79_005932 I79_005932 Ppp2r1a Ppp2r1a Tnfrsf12a Tnfrsf12a Tnf Tnf Inhba Inhba Psen2 Psen2 Gper1 Gper1 Itm2c Itm2c Traf2 Traf2 Bcl10 Bcl10 Pea15 Pea15 Dapk3 Dapk3 Srpx Srpx Bid Bid Fadd Fadd I79_012384 I79_012384 Runx3 Runx3 I79_011725 I79_011725 Stk4 Stk4 Stk3 Stk3 I79_010639 I79_010639 Casp8 Casp8 I79_000092 I79_000092 Wwox Wwox Skil Skil Thbs1 Thbs1 Sfrp1 Sfrp1 I79_009845 I79_009845 Pml Pml Bcl2l14 Bcl2l14 Cav1 Cav1 Hyal2 Hyal2 Unc5b Unc5b Trps1 Trps1 I79_003563 I79_003563 Agt Agt Faf1 Faf1 Ltbr Ltbr I79_001046 I79_001046 Pak2 Pak2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_014483Serine/threonine-protein kinase 3. (118 aa)
I79_005603Putative ubiquitin carboxyl-terminal hydrolase CYLD. (730 aa)
Jak3Tyrosine-protein kinase JAK3. (222 aa)
I79_005129Tyrosine-protein kinase JAK3. (330 aa)
Siglec1Sialoadhesin. (1708 aa)
Ppp2r1bSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform. (601 aa)
I79_003765Protein disulfide-isomerase A3. (444 aa)
Ppp1caSerine/threonine-protein phosphatase PP1-alpha catalytic subunit. (148 aa)
I79_018257Integral membrane protein 2C. (232 aa)
Agtr2Type-2 angiotensin II receptor-like protein; Belongs to the G-protein coupled receptor 1 family. (363 aa)
I79_018586Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN. (345 aa)
I79_019425Apoptosis-associated speck-like protein containing a CARD. (192 aa)
Htra2Serine protease HTRA2, mitochondrial. (448 aa)
Rbck1RanBP-type and C3HC4-type zinc finger-containing protein 1. (422 aa)
Atf3Cyclic AMP-dependent transcription factor ATF-3. (181 aa)
I79_022080Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (402 aa)
Ripk1Receptor-interacting serine/threonine-protein kinase 1. (655 aa)
I79_005932Tumor necrosis factor ligand superfamily member 10; Belongs to the tumor necrosis factor family. (253 aa)
Ppp2r1aSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (534 aa)
Tnfrsf12aTumor necrosis factor receptor superfamily member 12A. (124 aa)
TnfTumor necrosis factor; Belongs to the tumor necrosis factor family. (234 aa)
InhbaInhibin beta A chain-like protein. (424 aa)
Psen2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (448 aa)
Gper1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (371 aa)
Itm2cIntegral membrane protein 2C. (203 aa)
Traf2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
Bcl10B-cell lymphoma/leukemia 10. (232 aa)
Pea15Astrocytic phosphoprotein PEA-15. (130 aa)
Dapk3Death-associated protein kinase 3. (530 aa)
SrpxSushi repeat-containing protein SRPX. (340 aa)
BidBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (194 aa)
FaddFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
I79_012384Leukocyte common antigen. (962 aa)
Runx3Runt-related transcription factor 3. (299 aa)
I79_011725Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (249 aa)
Stk4Serine/threonine-protein kinase 4. (487 aa)
Stk3Serine/threonine-protein kinase 3. (260 aa)
I79_010639WW domain-containing oxidoreductase. (138 aa)
Casp8Caspase-8; Belongs to the peptidase C14A family. (481 aa)
I79_000092Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
WwoxWW domain-containing oxidoreductase. (193 aa)
SkilSki-like protein. (677 aa)
Thbs1Thrombospondin-1. (533 aa)
Sfrp1Secreted frizzled-related protein 1. (104 aa)
I79_009845Metalloproteinase inhibitor 3. (250 aa)
PmlPutative transcription factor PML. (540 aa)
Bcl2l14Apoptosis facilitator Bcl-2-like protein 14. (365 aa)
Cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
Hyal2Hyaluronidase. (359 aa)
Unc5bNetrin receptor UNC5B. (554 aa)
Trps1Zinc finger transcription factor Trps1. (395 aa)
I79_003563Zinc finger transcription factor Trps1. (151 aa)
AgtAngiotensinogen; Belongs to the serpin family. (477 aa)
Faf1FAS-associated factor 1. (645 aa)
LtbrTumor necrosis factor receptor superfamily member 3. (412 aa)
I79_001046Neurofibromin. (2164 aa)
Pak2Non-specific serine/threonine protein kinase. (524 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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