STRINGSTRING
Unc5b Unc5b Csf2 Csf2 I79_004195 I79_004195 Mcl1 Mcl1 Col2a1 Col2a1 I79_022036 I79_022036 Ripk1 Ripk1 I79_012727 I79_012727 Cx3cl1 Cx3cl1 I79_023808 I79_023808 I79_024415 I79_024415 Snai2 Snai2 Gdnf Gdnf Fyn Fyn I79_025454 I79_025454 Stradb Stradb Agap2 Agap2 I79_016446 I79_016446 Hspa1a Hspa1a Tnf Tnf IL1B IL1B Eya4 Eya4 I79_021341 I79_021341 I79_021786 I79_021786 Tert Tert I79_001733 I79_001733 Skor1 Skor1 Eya2 Eya2 Prdx2 Prdx2 Bcl2l10 Bcl2l10 I79_000117 I79_000117 Zc3hc1 Zc3hc1 Gata1 Gata1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Unc5bNetrin receptor UNC5B. (554 aa)
Csf2Granulocyte-macrophage colony-stimulating factor. (95 aa)
I79_004195Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (501 aa)
Mcl1Putative induced myeloid leukemia cell differentiation protein Mcl-1 like protein. (120 aa)
Col2a1Collagen alpha-1(II) chain. (709 aa)
I79_022036Peroxiredoxin-2. (108 aa)
Ripk1Receptor-interacting serine/threonine-protein kinase 1. (655 aa)
I79_012727Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (441 aa)
Cx3cl1Fractalkine. (335 aa)
I79_023808Induced myeloid leukemia cell differentiation protein Mcl-1-like. (118 aa)
I79_024415Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (755 aa)
Snai2Zinc finger protein SNAI2-like protein. (268 aa)
GdnfGlial cell line-derived neurotrophic factor. (160 aa)
FynProto-oncogene tyrosine-protein kinase Fyn. (232 aa)
I79_025454Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (182 aa)
StradbSTE20-related kinase adapter protein beta. (419 aa)
Agap2Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2. (829 aa)
I79_016446Heat shock 70 kDa protein 1A; Belongs to the heat shock protein 70 family. (641 aa)
Hspa1aHeat shock 70 kDa protein 1A/1B; Belongs to the heat shock protein 70 family. (641 aa)
TnfTumor necrosis factor; Belongs to the tumor necrosis factor family. (234 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa)
Eya4Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (468 aa)
I79_021341Serine/threonine-protein kinase Sgk3. (160 aa)
I79_021786Collagen alpha-1(II) chain. (689 aa)
TertTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (138 aa)
I79_001733Mitogen-activated protein kinase. (1186 aa)
Skor1Dual specificity mitogen-activated protein kinase kinase 5. (719 aa)
Eya2Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (550 aa)
Prdx2Peroxiredoxin-2. (198 aa)
Bcl2l10Bcl-2-like protein 10. (113 aa)
I79_000117GDNF family receptor alpha-like. (388 aa)
Zc3hc1Nuclear-interacting partner of ALK. (501 aa)
Gata1Erythroid transcription factor-like protein. (330 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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