STRINGSTRING
Nabp1 Nabp1 I79_000682 I79_000682 Rad51d Rad51d I79_025034 I79_025034 I79_024747 I79_024747 Chd4 Chd4 I79_002264 I79_002264 Ctc1 Ctc1 I79_003659 I79_003659 I79_003672 I79_003672 Tp53bp1 Tp53bp1 Hnrnpa2b1 Hnrnpa2b1 Xrcc5 Xrcc5 Upf1 Upf1 Tnks Tnks Stn1 Stn1 I79_024485 I79_024485 Nsmce1 Nsmce1 I79_023605 I79_023605 I79_022532 I79_022532 I79_022224 I79_022224 I79_021848 I79_021848 I79_020554 I79_020554 Chek1 Chek1 Men1 Men1 I79_018477 I79_018477 Terf2ip Terf2ip Sun2 Sun2 I79_017376 I79_017376 I79_016941 I79_016941 Mta2 Mta2 I79_016684 I79_016684 I79_016662 I79_016662 Sapcd1 Sapcd1 I79_016282 I79_016282 Dhx36 Dhx36 Recql4 Recql4 I79_015035 I79_015035 I79_014844 I79_014844 I79_014809 I79_014809 PIF1 PIF1 Ten1 Ten1 I79_014329 I79_014329 I79_013817 I79_013817 Nabp2 Nabp2 Dclre1b Dclre1b H671_21027 H671_21027 I79_012607 I79_012607 Magt1 Magt1 Brca2 Brca2 I79_011834 I79_011834 Rbbp7 Rbbp7 Kdm1a Kdm1a I79_010245 I79_010245 Smc6 Smc6 Hdac2 Hdac2 RTEL1 RTEL1 I79_009767 I79_009767 Pml Pml Pot1 Pot1 I79_008624 I79_008624 Tinf2 Tinf2 Gatad2b Gatad2b Dna2 Dna2 I79_007343 I79_007343 I79_007275 I79_007275 I79_007273 I79_007273 I79_007077 I79_007077 Srgap1 Srgap1 Znf827 Znf827 I79_006713 I79_006713 I79_006416 I79_006416 Wrn Wrn Cbx5 Cbx5 I79_026101 I79_026101 Smc5 Smc5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Nabp1SOSS complex subunit B2. (198 aa)
I79_000682Histone H3.3. (136 aa)
Rad51dDNA repair protein RAD51-like 4. (329 aa)
I79_025034Doublesex-and mab-3-related transcription factor 2. (508 aa)
I79_024747Zinc finger and SCAN domain-containing protein 4. (236 aa)
Chd4Chromodomain-helicase-DNA-binding protein 4. (1930 aa)
I79_002264Histone H3.3 type 1. (138 aa)
Ctc1Uncharacterized protein C17orf68-like. (1215 aa)
I79_003659Homeobox-containing protein 1. (219 aa)
I79_003672Pin2-interacting protein X1. (329 aa)
Tp53bp1Tumor suppressor p53-binding protein 1. (1952 aa)
Hnrnpa2b1Heterogeneous nuclear ribonucleoproteins A2/B1. (282 aa)
Xrcc5X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (732 aa)
Upf1Regulator of nonsense transcripts 1. (771 aa)
TnksPoly [ADP-ribose] polymerase. (897 aa)
Stn1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (378 aa)
I79_024485THO complex subunit 2. (1588 aa)
Nsmce1Non-structural maintenance of chromosomes element 1-like. (220 aa)
I79_023605Histone H3.3. (136 aa)
I79_022532Structural maintenance of chromosomes protein 5. (861 aa)
I79_022224Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (297 aa)
I79_021848Telomere-associated protein RIF1. (1602 aa)
I79_020554Protection of telomeres protein 1. (490 aa)
Chek1Serine/threonine-protein kinase Chk1; Belongs to the protein kinase superfamily. (476 aa)
Men1Menin. (610 aa)
I79_018477Zinc finger and BTB domain-containing protein 48. (741 aa)
Terf2ipTelomeric repeat-binding factor 2-interacting protein 1. (393 aa)
Sun2Protein unc-84-like B. (730 aa)
I79_017376Histone-binding protein RBBP7. (290 aa)
I79_016941Histone H3.3. (114 aa)
Mta2Metastasis-associated protein MTA2. (495 aa)
I79_016684Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (421 aa)
I79_016662Coiled-coil domain-containing protein 155. (629 aa)
Sapcd1Protein G7d. (147 aa)
I79_016282DNA repair protein XRCC1. (460 aa)
Dhx36Putative ATP-dependent RNA helicase DHX36. (922 aa)
Recql4ATP-dependent DNA helicase Q4. (561 aa)
I79_015035Zinc finger and BTB domain-containing protein 10. (370 aa)
I79_014844Histone H3.3. (140 aa)
I79_014809Histone H3.3 type 1. (89 aa)
PIF1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (637 aa)
Ten1Uncharacterized protein FLJ39785. (138 aa)
I79_014329Histone H3.3. (102 aa)
I79_013817NAD-dependent deacetylase sirtuin-6. (334 aa)
Nabp2SOSS complex subunit B1. (211 aa)
Dclre1b5' exonuclease Apollo-like protein. (527 aa)
H671_21027DNA excision repair protein ERCC-1. (111 aa)
I79_012607Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (568 aa)
Magt1Transcriptional regulator ATRX. (2344 aa)
Brca2Breast cancer type 2 susceptibility protein-like. (3008 aa)
I79_011834Breast cancer type 2 susceptibility protein-like. (143 aa)
Rbbp7Histone-binding protein RBBP7. (418 aa)
Kdm1aLysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (750 aa)
I79_010245Structural maintenance of chromosomes protein 6. (141 aa)
Smc6Structural maintenance of chromosomes protein 6. (54 aa)
Hdac2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (458 aa)
RTEL1Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1225 aa)
I79_009767Structural maintenance of chromosomes protein 6. (818 aa)
PmlPutative transcription factor PML. (540 aa)
Pot1Protection of telomeres protein 1. (375 aa)
I79_008624Protection of telomeres protein 1. (265 aa)
Tinf2TERF1-interacting nuclear factor 2. (413 aa)
Gatad2bTranscriptional repressor p66-beta. (590 aa)
Dna2DNA2-like helicase. (767 aa)
I79_007343DNA2-like helicase. (134 aa)
I79_007275Leucine-rich repeat and WD repeat-containing protein 1. (115 aa)
I79_007273Leucine-rich repeat and WD repeat-containing protein 1. (180 aa)
I79_007077SLIT-ROBO Rho GTPase-activating protein 1. (59 aa)
Srgap1SLIT-ROBO Rho GTPase-activating protein 1. (253 aa)
Znf827Zinc finger protein 827. (809 aa)
I79_006713WD repeat, SAM and U-box domain-containing protein 1. (353 aa)
I79_006416Histone H3.3. (117 aa)
WrnWerner syndrome ATP-dependent helicase-like. (1405 aa)
Cbx5Heterochromatin protein 1 alpha. (191 aa)
I79_026101E3 SUMO-protein ligase NSE2. (68 aa)
Smc5Structural maintenance of chromosomes protein 5. (80 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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