STRINGSTRING
Pola2 Pola2 Pold3 Pold3 Pold1 Pold1 Ddah2 Ddah2 I79_016081 I79_016081 I79_015395 I79_015395 Cdt1 Cdt1 Prim1 Prim1 Fan1 Fan1 Pold4 Pold4 Smarcal1 Smarcal1 Rpa2 Rpa2 Dars2 Dars2 I79_000834 I79_000834 Donson Donson Rpa3 Rpa3 C3H19orf53 C3H19orf53 Prim2 Prim2 Pold2 Pold2 CDC6 CDC6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Pola2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (600 aa)
Pold3DNA polymerase delta subunit 3. (462 aa)
Pold1DNA polymerase. (1056 aa)
Ddah2N(G),N(G)-dimethylarginine dimethylaminohydrolase 2. (348 aa)
I79_016081DNA polymerase. (1016 aa)
I79_015395Replication protein A 30 kDa subunit. (333 aa)
Cdt1DNA replication factor Cdt1. (553 aa)
Prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (419 aa)
Fan1Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1012 aa)
Pold4DNA polymerase delta subunit 4. (107 aa)
Smarcal1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (916 aa)
Rpa2Replication protein A 32 kDa subunit. (248 aa)
Dars2Aspartyl-tRNA synthetase, mitochondrial. (651 aa)
I79_000834Protein downstream neighbor of Son. (113 aa)
DonsonProtein downstream neighbor of Son. (188 aa)
Rpa3Replication protein A subunit-like protein. (121 aa)
C3H19orf53Leydig cell tumor 10 kDa protein-like. (95 aa)
Prim2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (507 aa)
Pold2DNA polymerase delta subunit 2. (487 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (561 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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