STRINGSTRING
Rag2 Rag2 Dars2 Dars2 I79_003360 I79_003360 Thsd7b Thsd7b I79_003878 I79_003878 I79_003879 I79_003879 Nfe2l2 Nfe2l2 Rpa2 Rpa2 I79_007077 I79_007077 I79_007135 I79_007135 I79_007209 I79_007209 I79_007210 I79_007210 Gtf2e1 Gtf2e1 I79_007758 I79_007758 Mbtd1 Mbtd1 I79_008082 I79_008082 Ep400 Ep400 Nfyc Nfyc C3H19orf53 C3H19orf53 Tinf2 Tinf2 Tead4 Tead4 I79_008624 I79_008624 Pot1 Pot1 I79_008687 I79_008687 I79_008695 I79_008695 I79_008702 I79_008702 I79_008705 I79_008705 CgPICR_009876 CgPICR_009876 I79_008713 I79_008713 I79_008720 I79_008720 Meaf6 Meaf6 I79_008940 I79_008940 Cdc45 Cdc45 Ikzf1 Ikzf1 Mrgbp Mrgbp Gins4 Gins4 Orc3 Orc3 Rpa3 Rpa3 I79_010912 I79_010912 Trex1 Trex1 Pold2 Pold2 I79_011871 I79_011871 Gata1 Gata1 I79_012445 I79_012445 I79_012727 I79_012727 I79_012823 I79_012823 I79_012828 I79_012828 I79_012831 I79_012831 Fan1 Fan1 I79_013026 I79_013026 I79_013122 I79_013122 Prim1 Prim1 Dbf4 Dbf4 I79_013678 I79_013678 I79_014329 I79_014329 Ten1 Ten1 I79_014809 I79_014809 Sp1 Sp1 I79_014844 I79_014844 Parp1 Parp1 I79_015070 I79_015070 H671_5g13839 H671_5g13839 I79_015166 I79_015166 I79_015234 I79_015234 I79_015238 I79_015238 I79_015395 I79_015395 Top1 Top1 Gtf2h3 Gtf2h3 Trrap Trrap I79_016019 I79_016019 I79_016081 I79_016081 I79_016082 I79_016082 I79_016309 I79_016309 I79_016346 I79_016346 CgPICR_014462 CgPICR_014462 CgPICR_009863 CgPICR_009863 CgPICR_014457 CgPICR_014457 Vps72 Vps72 Hhex Hhex I79_004825 I79_004825 Myog Myog Epc1 Epc1 CgPICR_011875 CgPICR_011875 I79_004973 I79_004973 Xrcc5 Xrcc5 Smarcal1 Smarcal1 Tnp1 Tnp1 I79_005208 I79_005208 I79_005256 I79_005256 I79_005358 I79_005358 Tmem232 Tmem232 Med1 Med1 I79_006020 I79_006020 I79_006026 I79_006026 I79_006027 I79_006027 Gins1 Gins1 I79_024984 I79_024984 I79_024903 I79_024903 Stn1 Stn1 I79_024170 I79_024170 Pola2 Pola2 Tcf7l2 Tcf7l2 I79_023605 I79_023605 I79_023440 I79_023440 Nfe2 Nfe2 I79_021905 I79_021905 Kat5 Kat5 I79_021761 I79_021761 Taf10 Taf10 I79_021251 I79_021251 I79_021155 I79_021155 I79_020971 I79_020971 I79_020783 I79_020783 Morf4l2 Morf4l2 Mcm5 Mcm5 Tbx4 Tbx4 Kdm5a Kdm5a Rad52 Rad52 Mcm2 Mcm2 I79_006416 I79_006416 Cdt1 Cdt1 Gins2 Gins2 I79_000259 I79_000259 I79_000598 I79_000598 I79_000682 I79_000682 Donson Donson I79_000834 I79_000834 I79_000882 I79_000882 Suz12 Suz12 Tbx5 Tbx5 Kdm1b Kdm1b CDC6 CDC6 I79_025921 I79_025921 I79_025902 I79_025902 CgPICR_009899 CgPICR_009899 Nfyb Nfyb Mcm4 Mcm4 Srgap1 Srgap1 Mcm3 Mcm3 Actl6a Actl6a I79_016941 I79_016941 Prim2 Prim2 Ddah2 Ddah2 Sapcd1 Sapcd1 I79_020554 I79_020554 Pold3 Pold3 Epc2 Epc2 I79_019375 I79_019375 Pold1 Pold1 I79_018563 I79_018563 Gtf2b Gtf2b I79_018217 I79_018217 Pold4 Pold4 I79_018105 I79_018105 I79_018104 I79_018104 I79_017833 I79_017833 Gins3 Gins3 I79_017613 I79_017613 I79_025034 I79_025034 Chd4 Chd4 Irf4 Irf4 I79_002264 I79_002264 Cenpa Cenpa I79_002659 I79_002659 I79_002820 I79_002820 Dmap1 Dmap1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Rag2V(D)J recombination-activating protein 2. (527 aa)
Dars2Aspartyl-tRNA synthetase, mitochondrial. (651 aa)
I79_003360Thrombospondin type-1 domain-containing protein 7B. (240 aa)
Thsd7bThrombospondin type-1 domain-containing protein 7B. (248 aa)
I79_003878Histone H2A; Belongs to the histone H2A family. (242 aa)
I79_003879Core histone macro-H2A.1. (155 aa)
Nfe2l2Nuclear factor erythroid 2-related factor 2. (588 aa)
Rpa2Replication protein A 32 kDa subunit. (248 aa)
I79_007077SLIT-ROBO Rho GTPase-activating protein 1. (59 aa)
I79_007135Homeobox protein Nkx-2.5. (223 aa)
I79_007209Cell division cycle 5-related protein. (188 aa)
I79_007210Cell division cycle 5-related protein. (89 aa)
Gtf2e1General transcription factor IIE subunit 1. (438 aa)
I79_007758MBT domain-containing protein 1. (169 aa)
Mbtd1MBT domain-containing protein 1. (469 aa)
I79_008082Cell division cycle 5-related protein. (585 aa)
Ep400E1A-binding protein p400. (1439 aa)
NfycNuclear transcription factor Y subunit gamma. (335 aa)
C3H19orf53Leydig cell tumor 10 kDa protein-like. (95 aa)
Tinf2TERF1-interacting nuclear factor 2. (413 aa)
Tead4Transcriptional enhancer factor TEF-3. (361 aa)
I79_008624Protection of telomeres protein 1. (265 aa)
Pot1Protection of telomeres protein 1. (375 aa)
I79_008687Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (134 aa)
I79_008695Histone H2A; Belongs to the histone H2A family. (129 aa)
I79_008702Histone H2A type 1; Belongs to the histone H2A family. (331 aa)
I79_008705Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
CgPICR_009876Histone H2A; Belongs to the histone H2A family. (130 aa)
I79_008713Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (98 aa)
I79_008720Histone H2B; Belongs to the histone H2B family. (127 aa)
Meaf6Chromatin modification-related protein MEAF6. (160 aa)
I79_008940Vacuolar protein sorting-associated protein 72-like. (276 aa)
Cdc45CDC45-related protein. (282 aa)
Ikzf1DNA-binding protein Ikaros. (489 aa)
MrgbpMRG-binding protein. (148 aa)
Gins4DNA replication complex GINS protein SLD5. (375 aa)
Orc3Origin recognition complex subunit 3. (303 aa)
Rpa3Replication protein A subunit-like protein. (121 aa)
I79_010912Spermatid-specific linker histone H1-like protein. (174 aa)
Trex1Three prime repair exonuclease 1. (320 aa)
Pold2DNA polymerase delta subunit 2. (487 aa)
I79_011871Histone H2A; Belongs to the histone H2A family. (128 aa)
Gata1Erythroid transcription factor-like protein. (330 aa)
I79_012445Cell division cycle 5-related protein. (151 aa)
I79_012727Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (441 aa)
I79_012823Histone H2A; Belongs to the histone H2A family. (130 aa)
I79_012828Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (199 aa)
I79_012831Histone H2A; Belongs to the histone H2A family. (130 aa)
Fan1Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1012 aa)
I79_013026Histone H3.3. (50 aa)
I79_013122Nuclear transcription factor Y subunit beta. (246 aa)
Prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (419 aa)
Dbf4Protein DBF4-like A. (358 aa)
I79_013678Putative oxidoreductase GLYR1. (462 aa)
I79_014329Histone H3.3. (102 aa)
Ten1Uncharacterized protein FLJ39785. (138 aa)
I79_014809Histone H3.3 type 1. (89 aa)
Sp1Transcription factor Sp1. (778 aa)
I79_014844Histone H3.3. (140 aa)
Parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (971 aa)
I79_015070Inhibitor of growth protein. (333 aa)
H671_5g13839Cell division cycle 5-related protein. (242 aa)
I79_015166Cell division cycle 5-related protein. (90 aa)
I79_015234Mortality factor 4-like protein 2. (1078 aa)
I79_015238Mortality factor 4-like protein 2. (1782 aa)
I79_015395Replication protein A 30 kDa subunit. (333 aa)
Top1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (715 aa)
Gtf2h3General transcription factor IIH subunit 3. (313 aa)
TrrapTransformation/transcription domain-associated protein. (1999 aa)
I79_016019Transformation/transcription domain-associated protein; Belongs to the PI3/PI4-kinase family. (950 aa)
I79_016081DNA polymerase. (1016 aa)
I79_016082Mortality factor 4-like protein 1. (198 aa)
I79_016309Histone H2A; Belongs to the histone H2A family. (123 aa)
I79_016346Vacuolar protein sorting-associated protein 72-like. (193 aa)
CgPICR_014462Histone H2B; Belongs to the histone H2B family. (126 aa)
CgPICR_009863Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
CgPICR_014457Histone H2A; Belongs to the histone H2A family. (130 aa)
Vps72Vacuolar protein sorting-associated protein 72-like. (466 aa)
HhexHematopoietically-expressed homeobox protein Hhex. (98 aa)
I79_004825Histone H2A; Belongs to the histone H2A family. (128 aa)
MyogMyogenin. (224 aa)
Epc1Enhancer of polycomb-like 1. (173 aa)
CgPICR_011875Histone H2A; Belongs to the histone H2A family. (128 aa)
I79_004973Mortality factor 4-like protein 2. (438 aa)
Xrcc5X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (732 aa)
Smarcal1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (916 aa)
Tnp1Spermatid nuclear transition protein 1. (109 aa)
I79_005208Histone H2A; Belongs to the histone H2A family. (128 aa)
I79_005256Uncharacterized protein. (224 aa)
I79_005358Estrogen receptor beta. (58 aa)
Tmem232Uncharacterized protein. (354 aa)
Med1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1581 aa)
I79_006020Mortality factor 4-like protein 2. (938 aa)
I79_006026Mortality factor 4-like protein 2. (177 aa)
I79_006027Mortality factor 4-like protein 2. (668 aa)
Gins1DNA replication complex GINS protein PSF1. (161 aa)
I79_024984Histone H2A; Belongs to the histone H2A family. (119 aa)
I79_024903Histone H2A; Belongs to the histone H2A family. (103 aa)
Stn1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (378 aa)
I79_024170MRG-binding protein. (71 aa)
Pola2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (600 aa)
Tcf7l2Transcription factor 7-like 1. (73 aa)
I79_023605Histone H3.3. (136 aa)
I79_023440Histone H2A; Belongs to the histone H2A family. (119 aa)
Nfe2Transcription factor NF-E2 45 kDa subunit. (374 aa)
I79_021905Putative histone H3-like. (50 aa)
Kat5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa)
I79_021761Histone H2A; Belongs to the histone H2A family. (89 aa)
Taf10Transcription initiation factor TFIID subunit 10. (125 aa)
I79_021251High mobility group protein HMG-I/HMG-Y. (70 aa)
I79_021155Paired box protein Pax-2. (503 aa)
I79_020971Nucleophosmin. (280 aa)
I79_020783Transcription factor 7-like 2. (451 aa)
Morf4l2Mortality factor 4-like protein 2. (197 aa)
Mcm5DNA helicase; Belongs to the MCM family. (734 aa)
Tbx4T-box transcription factor TBX4. (688 aa)
Kdm5aLysine-specific demethylase 5A. (1608 aa)
Rad52DNA repair protein RAD52-like. (419 aa)
Mcm2DNA helicase; Belongs to the MCM family. (905 aa)
I79_006416Histone H3.3. (117 aa)
Cdt1DNA replication factor Cdt1. (553 aa)
Gins2DNA replication complex GINS protein PSF2. (97 aa)
I79_000259DNA replication complex GINS protein PSF2. (61 aa)
I79_000598Mortality factor 4-like protein 2. (737 aa)
I79_000682Histone H3.3. (136 aa)
DonsonProtein downstream neighbor of Son. (188 aa)
I79_000834Protein downstream neighbor of Son. (113 aa)
I79_000882Mortality factor 4-like protein 1. (96 aa)
Suz12Polycomb protein Suz12. (200 aa)
Tbx5T-box transcription factor TBX5. (518 aa)
Kdm1bLysine-specific histone demethylase 1B. (822 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (561 aa)
I79_025921YEATS domain-containing protein 4. (72 aa)
I79_025902DNA replication licensing factor MCM2. (182 aa)
CgPICR_009899Histone H2A; Belongs to the histone H2A family. (130 aa)
NfybNuclear transcription factor Y subunit beta. (169 aa)
Mcm4DNA helicase; Belongs to the MCM family. (862 aa)
Srgap1SLIT-ROBO Rho GTPase-activating protein 1. (253 aa)
Mcm3DNA helicase; Belongs to the MCM family. (807 aa)
Actl6aActin-like protein 6A; Belongs to the actin family. (429 aa)
I79_016941Histone H3.3. (114 aa)
Prim2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (507 aa)
Ddah2N(G),N(G)-dimethylarginine dimethylaminohydrolase 2. (348 aa)
Sapcd1Protein G7d. (147 aa)
I79_020554Protection of telomeres protein 1. (490 aa)
Pold3DNA polymerase delta subunit 3. (462 aa)
Epc2Enhancer of polycomb homolog. (706 aa)
I79_019375Mortality factor 4-like protein 2. (209 aa)
Pold1DNA polymerase. (1056 aa)
I79_018563Mortality factor 4-like protein 2. (645 aa)
Gtf2bTranscription initiation factor IIB. (285 aa)
I79_018217Histone H2B type 2-F; Belongs to the histone H2B family. (73 aa)
Pold4DNA polymerase delta subunit 4. (107 aa)
I79_018105Mortality factor 4-like protein 1. (70 aa)
I79_018104DNA replication complex GINS protein PSF2. (188 aa)
I79_017833Lymphoid enhancer-binding factor 1. (276 aa)
Gins3DNA replication complex GINS protein PSF3. (216 aa)
I79_017613DNA-dependent protein kinase catalytic subunit; Belongs to the PI3/PI4-kinase family. (3486 aa)
I79_025034Doublesex-and mab-3-related transcription factor 2. (508 aa)
Chd4Chromodomain-helicase-DNA-binding protein 4. (1930 aa)
Irf4Interferon regulatory factor 4. (418 aa)
I79_002264Histone H3.3 type 1. (138 aa)
CenpaHistone H3-like centromeric protein A. (129 aa)
I79_002659High mobility group protein HMGI-C. (103 aa)
I79_002820Histone H2A; Belongs to the histone H2A family. (106 aa)
Dmap1DNA methyltransferase 1-associated protein 1. (468 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
Server load: low (12%) [HD]